TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T20776	Fru-2,6-P2ase 2/6PF-2-K	B34FED	5-(4-Acetylaminophenoxy)-2-amino-1H-indole-3-carbonitrile	Investigative	9815029	C17H14N4O2	306.32	CC(=O)NC1=CC=C(C=C1)OC2=CC3=C(C=C2)NC(=C3C#N)N	IC50 ~ 100000 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	B36JKM	Schembl21856723	Investigative	118735780	C23H24N4O2	388.5	CCN1C=C(C2=C1C=CC(=C2)OC3=CC=C(C=C3)N(C)C(=O)[C@@H]4CCCN4)C#N	IC50 = 76500 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	B6T8ZY	Schembl21856804	Investigative	118735144	C24H26N4O3S	450.6	CC(C)CN1C=C(C2=C1C=CC(=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)[C@@H]4CCCN4)C#N	IC50 ~ 100000 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	B85FMH	2-Azanyl-N-[4-[(3-Cyano-1h-Indol-5-Yl)oxy]phenyl]ethanamide	Investigative	91668556	C17H14N4O2	306.32	C1=CC(=CC=C1NC(=O)CN)OC2=CC3=C(C=C2)NC=C3C#N	IC50 = 63200 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	BB6TG7	(2R)-2-Amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]-3-hydroxypropanamide	Investigative	118735772	C18H17N5O3	351.4	C1=CC(=CC=C1NC(=O)[C@@H](CO)N)OC2=CC3=C(C=C2)NC(=C3C#N)N	IC50 ~ 100000 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	BI5YF4	Schembl21856730	Investigative	118735785	C24H27N5O2	417.5	CN(C)CCN1C=C(C2=C1C=CC(=C2)OC3=CC=C(C=C3)NC(=O)[C@@H]4CCCN4)C#N	IC50 ~ 100000 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	BL2K0B	CCn1cc(C#N)c2cc(Oc3ccc(NC(=O)CN(C)C)cc3)ccc12	Investigative	118735777	C21H22N4O2	362.4	CCN1C=C(C2=C1C=CC(=C2)OC3=CC=C(C=C3)NC(=O)CN(C)C)C#N	IC50 = 76100 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	BR9B4H	2-Amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]acetamide	Investigative	9858287	C17H15N5O2	321.33	C1=CC(=CC=C1NC(=O)CN)OC2=CC3=C(C=C2)NC(=C3C#N)N	IC50 = 53800 nM	Poor binder
T20776	Fru-2,6-P2ase 2/6PF-2-K	BT5F4S	Schembl21856796	Investigative	118735779	C22H22N4O2	374.4	CCN1C=C(C2=C1C=CC(=C2)OC3=CC=C(C=C3)NC(=O)[C@H]4CCCN4)C#N	IC50 ~ 100000 nM	Poor binder