TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T17523	Sphingosine-1-phosphate receptor 4	B0QTB3	5-Cyclopropyl-N,N-bis(2-methylcyclohexyl)-1,2-oxazole-3-carboxamide	Investigative	25110496	C21H32N2O2	344.5	CC1CCCCC1N(C2CCCCC2C)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B0S6HN	1-[(7-Naphthalen-2-yl-1-benzothiophen-2-yl)methyl]azetidine-3-carboxylic acid	Investigative	134131291	C23H19NO2S	373.5	C1C(CN1CC2=CC3=C(S2)C(=CC=C3)C4=CC5=CC=CC=C5C=C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B2NTB9	N-Cyclohexyl-5-cyclopropyl-N-(2-methylcyclohexyl)-1,2-oxazole-3-carboxamide	Investigative	25110498	C20H30N2O2	330.5	CC1CCCCC1N(C2CCCCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B37OZG	3-[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]-2-methylpropanoic acid	Investigative	134130146	C21H23NO2S	353.5	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CNCC(C)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B4J6YM	3-[[4-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]propanoic acid	Investigative	134131038	C20H21NO2S	339.5	CCC1=CC=CC=C1C2=C3C=C(SC3=CC=C2)CNCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B4M2FA	4-[[[4-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]methyl]benzoic acid	Investigative	134131043	C25H23NO2S	401.5	CCC1=CC=CC=C1C2=C3C=C(SC3=CC=C2)CNCC4=CC=C(C=C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B71WOI	4-[[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]methyl]benzoic acid	Investigative	134131495	C25H23NO2S	401.5	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CNCC4=CC=C(C=C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B8C2JN	1-[(5-Naphthalen-2-yl-1-benzothiophen-2-yl)methyl]azetidine-3-carboxylic acid	Investigative	134130169	C23H19NO2S	373.5	C1C(CN1CC2=CC3=C(S2)C=CC(=C3)C4=CC5=CC=CC=C5C=C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	B9FK5Y	N,N-Dicyclohexyl-5-(4-methoxyphenyl)-1,2-oxazole-3-carboxamide	Investigative	25110484	C23H30N2O3	382.5	COC1=CC=C(C=C1)C2=CC(=NO2)C(=O)N(C3CCCCC3)C4CCCCC4	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BAY37Q	2-[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]acetic acid	Investigative	134130960	C19H19NO2S	325.4	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CNCC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BC19LT	2-[4-[(5-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]phenyl]acetic acid	Investigative	134130704	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=CC4=C(C=C3)SC(=C4)CNC5=CC=C(C=C5)CC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BEZ3M1	4-[[(5-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid	Investigative	134130243	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=CC4=C(C=C3)SC(=C4)CNCC5=CC=C(C=C5)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BG0W7S	N-Cycloheptyl-5-cyclopropyl-N-(2-methylcyclohexyl)-1,2-oxazole-3-carboxamide	Investigative	25110499	C21H32N2O2	344.5	CC1CCCCC1N(C2CCCCCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BGXS76	3-[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]propanoic acid	Investigative	134130022	C20H21NO2S	339.5	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CNCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BJ6C3D	2-[3-[(5-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]phenyl]acetic acid	Investigative	134131316	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=CC4=C(C=C3)SC(=C4)CNC5=CC=CC(=C5)CC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BJL58W	2-Amino-3-[[4-(2-ethylphenyl)-1-benzothiophen-2-yl]methylamino]propanoic acid	Investigative	134130071	C20H22N2O2S	354.5	CCC1=CC=CC=C1C2=C3C=C(SC3=CC=C2)CNCC(C(=O)O)N	EC50 = 57600 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BK1GQ4	N,N-Dicyclohexyl[5-(methylethyl)isoxazol-3-yl]carboxamide	Investigative	17253281	C19H30N2O2	318.5	CC(C)C1=CC(=NO1)C(=O)N(C2CCCCC2)C3CCCCC3	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BLOK46	1-[[4-(2-Ethylphenyl)-1-benzothiophen-2-yl]methyl]azetidine-3-carboxylic acid	Investigative	134130538	C21H21NO2S	351.5	CCC1=CC=CC=C1C2=C3C=C(SC3=CC=C2)CN4CC(C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BNC0D7	N,N-Dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide	Investigative	17253208	C19H28N2O2	316.4	C1CCC(CC1)N(C2CCCCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BPH2S4	2-(7-(5-(3-Cyano-5-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acid	Investigative	44138103	C23H15F3N4O4	468.4	C1CN2C3=C(C=C(C=C3)C4=NOC(=N4)C5=CC(=CC(=C5)C#N)OC(F)(F)F)C=C2C1CC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BR74WC	N,N-Dicyclohexyl-5-phenyl-1,2-oxazole-3-carboxamide	Investigative	25110488	C22H28N2O2	352.5	C1CCC(CC1)N(C2CCCCC2)C(=O)C3=NOC(=C3)C4=CC=CC=C4	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BR7MV0	2-[[4-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]acetic acid	Investigative	134130203	C19H19NO2S	325.4	CCC1=CC=CC=C1C2=C3C=C(SC3=CC=C2)CNCC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BS45MD	S1P1 Agonist III	Investigative	54764919	C21H16F3N3O3	415.4	COC1=C(C=NC=C1)C(=O)NC(=O)NC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BT5W9N	5-[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]pentanoic acid	Investigative	134130188	C22H25NO2S	367.5	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CNCCCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BTP8G2	4-[[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid	Investigative	134130548	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCC5=CC=C(C=C5)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BVGI57	4-[[(7-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid	Investigative	134130183	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=CC=CC4=C3SC(=C4)CNCC5=CC=C(C=C5)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BW05GV	2-[4-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]phenyl]acetic acid	Investigative	134131130	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNC5=CC=C(C=C5)CC(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BWM42X	N,N-Dicyclohexyl-5-propyl-3-isoxazolecarboxamide	Investigative	5309153	C19H30N2O2	318.5	CCCC1=CC(=NO1)C(=O)N(C2CCCCC2)C3CCCCC3	EC50 ~ 50000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BX6I8B	1-[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methyl]azetidine-3-carboxylic acid	Investigative	134131039	C21H21NO2S	351.5	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CN4CC(C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T17523	Sphingosine-1-phosphate receptor 4	BZ0FP5	4-[[7-(2-Ethylphenyl)-1-benzothiophen-2-yl]methylamino]butanoic acid	Investigative	134130622	C21H23NO2S	353.5	CCC1=CC=CC=C1C2=CC=CC3=C2SC(=C3)CNCCCC(=O)O	EC50 ~ 100000 nM	Poor binder