TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T14945 Centromeric protein E D0V2YJ MK-0731 Phase 1 11655511 C25H28F3N3O2 459.5 CN1CC[C@@H]([C@@H](C1)F)N(C)C(=O)N2CC(=C[C@@]2(CO)C3=CC=CC=C3)C4=C(C=CC(=C4)F)F IC50 ~ 50000 nM Poor binder T14945 Centromeric protein E B1ZB4C Physodic acid Investigative 65751 C26H30O8 470.5 CCCCCC1=C(C(=CC2=C1OC3=CC(=CC(=C3C(=O)O2)CC(=O)CCCCC)O)O)C(=O)O IC50 = 91400 nM Poor binder