TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	D0L8WH	ABT-737	Terminated	11228183	C42H45ClN6O5S2	813.4	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B02DVO	(E)-3-(1,3-Benzodioxol-5-yl)-1-(2-hydroxy-3,4,5-trimethoxyphenyl)prop-2-en-1-one	Investigative	127048680	C19H18O7	358.3	COC1=C(C(=C(C(=C1)C(=O)/C=C/C2=CC3=C(C=C2)OCO3)O)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B0KXC4	2-((4-(4-Bromophenylsulfonamido)-1-methoxynaphthalen-2-yl)thio)acetic acid	Investigative	86730609	C19H16BrNO5S2	482.4	COC1=C(C=C(C2=CC=CC=C21)NS(=O)(=O)C3=CC=C(C=C3)Br)SCC(=O)O	Ki = 86980 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B1NQK0	4-Aminosulphonyl-1-hydroxy-2-naphthoic acid	Investigative	97423	C11H9NO5S	267.26	C1=CC=C2C(=C1)C(=CC(=C2O)C(=O)O)S(=O)(=O)N	Ki = 99000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B1ZG0T	(E)-1-(2,3-Dihydro-1-benzofuran-5-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one	Investigative	25990016	C17H14O3	266.29	C1COC2=C1C=C(C=C2)C(=O)/C=C/C3=CC=C(C=C3)O	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B2O6CI	(E)-3-(3-Chloro-5-fluoro-4-hydroxyphenyl)-1-pyridin-4-ylprop-2-en-1-one	Investigative	127048965	C14H9ClFNO2	277.68	C1=CN=CC=C1C(=O)/C=C/C2=CC(=C(C(=C2)Cl)O)F	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B3KE5R	4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitro-N-(4-piperazin-1-ylphenyl)benzenesulfonamide	Investigative	57523431	C28H36N6O4S2	584.8	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)N4CCNCC4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B42SQN	2,3-Dihydro[1,4]thiazino[2,3,4-hi]indole-5-carboxylic acid	Investigative	53213045	C11H9NO2S	219.26	C1CSC2=CC=CC3=C2N1C(=C3)C(=O)O	Ki = 51000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B43JSL	(E)-1-(2-Hydroxy-3,4,5-trimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one	Investigative	127049968	C19H20O6	344.4	COC1=CC=C(C=C1)/C=C/C(=O)C2=CC(=C(C(=C2O)OC)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B46OHZ	(E)-1-(6-Hydroxy-2,3,4-trimethoxyphenyl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one	Investigative	127050261	C19H17F3O5	382.3	COC1=C(C(=C(C(=C1)O)C(=O)/C=C/C2=CC=C(C=C2)C(F)(F)F)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B47ZAH	5-(4-Aminophenyl)sulfanyl-2-oxo-1H-pyridine-3-carbonitrile	Investigative	71575287	C12H9N3OS	243.29	C1=CC(=CC=C1N)SC2=CNC(=O)C(=C2)C#N	IC50 = 133300 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B4JAZ3	4-(Benzylsulfamoyl)-1-hydroxynaphthalene-2-carboxylic acid	Investigative	126480867	C18H15NO5S	357.4	C1=CC=C(C=C1)CNS(=O)(=O)C2=CC(=C(C3=CC=CC=C32)O)C(=O)O	Ki = 56300 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B4LJN0	delta(Sup 1),alpha-Acenaphthenemalononitrile, 2-oxo-	Investigative	96894	C15H6N2O	230.22	C1=CC2=C3C(=C1)C(=C(C#N)C#N)C(=O)C3=CC=C2	IC50 = 71500 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B4NR1J	4-[4-[[2-(4-Chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-(propan-2-ylamino)-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide	Investigative	72793104	C36H42ClF3N4O5S2	767.3	CC(C)NC1=C(C=C(C=C1)S(=O)(=O)NC(=O)C2=CC=C(C=C2)N3CCN(CC3)CC4=C(CCC(C4)(C)C)C5=CC=C(C=C5)Cl)S(=O)(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B5FT1K	2-Hydroxynicotinonitrile	Investigative	577543	C6H4N2O	120.11	C1=CNC(=O)C(=C1)C#N	Ki = 109000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B5M9WZ	2-[1-Hydroxy-4-[(2-phenylacetyl)amino]naphthalen-2-yl]sulfanylacetic acid	Investigative	71549004	C20H17NO4S	367.4	C1=CC=C(C=C1)CC(=O)NC2=CC(=C(C3=CC=CC=C32)O)SCC(=O)O	Ki = 59350 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B5YQ2V	2-[4-(Benzenesulfonamidomethyl)-1-hydroxynaphthalen-2-yl]sulfanylacetic acid	Investigative	90656475	C19H17NO5S2	403.5	C1=CC=C(C=C1)S(=O)(=O)NCC2=CC(=C(C3=CC=CC=C32)O)SCC(=O)O	Ki = 64750 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B68NET	4-[(2-Chlorophenyl)methylsulfamoyl]-1-hydroxynaphthalene-2-carboxylic acid	Investigative	126480723	C18H14ClNO5S	391.8	C1=CC=C(C(=C1)CNS(=O)(=O)C2=CC(=C(C3=CC=CC=C32)O)C(=O)O)Cl	Ki = 50300 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B69UQH	3,7-Dimethyl-benzofuran-2-carboxylic acid	Investigative	3163284	C11H10O3	190.19	CC1=C2C(=CC=C1)C(=C(O2)C(=O)O)C	Ki = 102000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B7BG5Q	Chembl4218364	Investigative	145969619	C25H26ClNO5S	488	CC1=CC(=CC(=C1Cl)C)OC2=CC=C(C=C2)/C=C\\3/C(=O)N(C(=O)S3)[C@@H](CC(C)C)C(=O)OC	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B7LD0Y	Nvp-cgm097	Investigative	53240420	C38H47ClN4O4	659.3	CC(C)OC1=C(C=C2CC(=O)N([C@H](C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B7QE2N	N-(4-Hydroxynaphthalen-1-yl)benzenesulfonamide	Investigative	694880	C16H13NO3S	299.3	C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C3=CC=CC=C32)O	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B7UE5G	(E)-1-(2,3-Dihydro-1-benzofuran-5-yl)-3-(3-fluoro-4-hydroxyphenyl)prop-2-en-1-one	Investigative	127048679	C17H13FO3	284.28	C1COC2=C1C=C(C=C2)C(=O)/C=C/C3=CC(=C(C=C3)O)F	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B81ZSA	2-Hydroxy-5-(methylsulfanyl)benzoic acid	Investigative	597283	C8H8O3S	184.21	CSC1=CC(=C(C=C1)O)C(=O)O	IC50 = 160000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B83TIC	Chembl4225591	Investigative	145967616	C19H12BrNO4	398.2	C1OC2=C(O1)C=C(C=C2)C3=NC(=CC(=C3)C4=CC=C(C=C4)Br)C(=O)O	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B85PRN	5,6,7-Trimethoxy-2-(2-nitrophenyl)chromen-4-one	Investigative	127048682	C18H15NO7	357.3	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3[N+](=O)[O-])OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B8X6TV	Chembl4202491	Investigative	145978663	C18H14ClNO3S	359.8	CC1=CC(=CC(=C1Cl)C)OC2=CC=C(C=C2)/C=C\\3/C(=O)NC(=O)S3	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B8ZV7I	5-(4-Bromophenyl)sulfanyl-2-oxo-1H-pyridine-3-carbonitrile	Investigative	71575286	C12H7BrN2OS	307.17	C1=CC(=CC=C1SC2=CNC(=O)C(=C2)C#N)Br	IC50 = 121100 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B94PAM	(E)-3-(2-Hydroxy-4-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one	Investigative	14157895	C16H14O4	270.28	COC1=CC(=C(C=C1)/C=C/C(=O)C2=CC=C(C=C2)O)O	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B95XIE	(E)-1-(2-Hydroxy-3,4,5-trimethoxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one	Investigative	127048637	C18H17NO7	359.3	COC1=C(C(=C(C(=C1)C(=O)/C=C/C2=CC=C(C=C2)[N+](=O)[O-])O)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B9B1XO	(2S)-2-[(2S,3R)-10-[(4-Fluorophenyl)sulfonylamino]-3-methyl-2-[[methyl(naphthalen-1-ylcarbamoyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5-yl]propanoic acid	Investigative	118723163	C33H33FN4O7S	648.7	C[C@@H]1CN(C(=O)C2=C(C(=CC=C2)NS(=O)(=O)C3=CC=C(C=C3)F)O[C@@H]1CN(C)C(=O)NC4=CC=CC5=CC=CC=C54)[C@@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B9BG6E	(E)-3-(3,5-Difluoro-4-hydroxyphenyl)-1-(2,3-dihydro-1-benzofuran-5-yl)prop-2-en-1-one	Investigative	127049283	C17H12F2O3	302.27	C1COC2=C1C=C(C=C2)C(=O)/C=C/C3=CC(=C(C(=C3)F)O)F	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B9GW0B	5-(4-Chlorophenyl)-1,2-dimethyl-N-[3-(4-methylpiperazin-1-yl)propyl]-4-phenylpyrrole-3-carboxamide	Investigative	60171063	C27H33ClN4O	465	CC1=C(C(=C(N1C)C2=CC=C(C=C2)Cl)C3=CC=CC=C3)C(=O)NCCCN4CCN(CC4)C	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	B9P2IZ	4'-Amino-5,6,7-trimethoxyflavone	Investigative	10019325	C18H17NO5	327.3	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)N)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BA9U6V	2-(2-Aminophenyl)-5,6,7-trimethoxychromen-4-one	Investigative	127049010	C18H17NO5	327.3	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3N)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BB2VI3	5-(4-Methylphenyl)sulfanyl-2-oxo-1H-pyridine-3-carbonitrile	Investigative	71575181	C13H10N2OS	242.3	CC1=CC=C(C=C1)SC2=CNC(=O)C(=C2)C#N	IC50 = 63100 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BBVP97	Chembl4203274	Investigative	145978226	C16H17NO5S	335.4	CC(C)C[C@@H](C(=O)O)N1C(=O)/C(=C/C2=CC=C(C=C2)O)/SC1=O	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BDL1W8	5-(4-Chlorophenyl)-4-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylcarbamoyl]phenyl]piperazin-1-yl]phenyl]-1,2-dimethyl-N-[3-(4-methylpiperazin-1-yl)propyl]pyrrole-3-carboxamide	Investigative	60169703	C56H67ClN10O6S2	1075.8	CC1=C(C(=C(N1C)C2=CC=C(C=C2)Cl)C3=CC(=CC=C3)N4CCN(CC4)C5=CC=C(C=C5)C(=O)NS(=O)(=O)C6=CC(=C(C=C6)N[C@H](CCN(C)C)CSC7=CC=CC=C7)[N+](=O)[O-])C(=O)NCCCN8CCN(CC8)C	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BE1XD4	Naphtho[1,2-d][1,3]oxazol-2-ol	Investigative	3701653	C11H7NO2	185.18	C1=CC=C2C(=C1)C=CC3=C2NC(=O)O3	IC50 = 130000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BF3AZ9	5-Chloro-3-methyl-1-benzofuran-2-carboxylic acid	Investigative	865778	C10H7ClO3	210.61	CC1=C(OC2=C1C=C(C=C2)Cl)C(=O)O	Ki = 52000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BFGE04	3-(1-Naphthylmethylsulfanyl)-1H-1,2,4-triazole	Investigative	719016	C13H11N3S	241.31	C1=CC=C2C(=C1)C=CC=C2CSC3=NC=NN3	Ki = 86000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BFM13G	(E)-1-(6-Hydroxy-2,3,4-trimethoxyphenyl)-3-(2-nitrophenyl)prop-2-en-1-one	Investigative	127049967	C18H17NO7	359.3	COC1=C(C(=C(C(=C1)O)C(=O)/C=C/C2=CC=CC=C2[N+](=O)[O-])OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BH1N9X	(E)-1-(4-Hydroxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one	Investigative	16380269	C14H11NO2	225.24	C1=CC(=CC=C1C(=O)/C=C/C2=CC=NC=C2)O	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BHI39R	(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-N-(3-nitrophenyl)sulfonyl-3-phenylpropanamide	Investigative	122194476	C31H25ClN4O7S	633.1	C1=CC=C(C=C1)C[C@@H](C(=O)NS(=O)(=O)C2=CC=CC(=C2)[N+](=O)[O-])N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BI3FC4	3-(4-Chloro-3,5-dimethylphenoxy)propanoic acid	Investigative	22683787	C11H13ClO3	228.67	CC1=CC(=CC(=C1Cl)C)OCCC(=O)O	Ki = 60000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BI48UO	2-[1-Methoxy-4-[(3-phenylphenyl)sulfonylamino]naphthalen-2-yl]sulfanylacetic acid	Investigative	89493712	C25H21NO5S2	479.6	COC1=C(C=C(C2=CC=CC=C21)NS(=O)(=O)C3=CC=CC(=C3)C4=CC=CC=C4)SCC(=O)O	IC50 = 58430 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BI61ZV	5,6,7-Trimethoxy-2-[4-(trifluoromethyl)phenyl]chromen-4-one	Investigative	127048681	C19H15F3O5	380.3	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)C(F)(F)F)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BIB6Z8	3-(3-Quinolin-6-yloxypropyl)-1H-indole-2-carboxylic acid	Investigative	71545646	C21H18N2O3	346.4	C1=CC=C2C(=C1)C(=C(N2)C(=O)O)CCCOC3=CC4=C(C=C3)N=CC=C4	Ki = 62000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BJ3EM1	4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid	Investigative	25058455	C26H31ClN2O2	439	CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)O)C4=CC=C(C=C4)Cl)C	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BJT07A	(2E)-3-(4-Hydroxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one	Investigative	5927890	C16H14O3	254.28	COC1=CC=C(C=C1)C(=O)/C=C/C2=CC=C(C=C2)O	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BJX7A4	(E)-1-(2-Hydroxy-3,4,5-trimethoxyphenyl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one	Investigative	127049969	C19H17F3O5	382.3	COC1=C(C(=C(C(=C1)C(=O)/C=C/C2=CC=C(C=C2)C(F)(F)F)O)OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BL1I4Q	2-[1-Methoxy-4-[(4-phenylphenyl)sulfonylamino]naphthalen-2-yl]sulfanylacetic acid	Investigative	71548705	C25H21NO5S2	479.6	COC1=C(C=C(C2=CC=CC=C21)NS(=O)(=O)C3=CC=C(C=C3)C4=CC=CC=C4)SCC(=O)O	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BL3OZ7	Chembl4203453	Investigative	145977281	C24H25ClN2O4S	473	CC1=CC(=CC(=C1Cl)C)OC2=CC=C(C=C2)/C=C\\3/C(=O)N(C(=O)S3)[C@@H](CC(C)C)C(=O)N	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BLV93P	2-[1-Hydroxy-4-(methanesulfonamido)naphthalen-2-yl]sulfanylacetic acid	Investigative	71549413	C13H13NO5S2	327.4	CS(=O)(=O)NC1=CC(=C(C2=CC=CC=C21)O)SCC(=O)O	Ki = 74920 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BLVO41	(E)-1-(6-Hydroxy-2,3,4-trimethoxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one	Investigative	11245319	C18H17NO7	359.3	COC1=C(C(=C(C(=C1)O)C(=O)/C=C/C2=CC=C(C=C2)[N+](=O)[O-])OC)OC	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BLX74B	3-[1-Hydroxy-4-(naphthalen-1-ylsulfonylamino)naphthalen-2-yl]sulfanylpropanoic acid	Investigative	40852065	C23H19NO5S2	453.5	C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)NC3=CC(=C(C4=CC=CC=C43)O)SCCC(=O)O	IC50 = 64900 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BN6X4G	7-Methyl-3-phenyl-1H-indole-2-carboxylic acid	Investigative	16645886	C16H13NO2	251.28	CC1=C2C(=CC=C1)C(=C(N2)C(=O)O)C3=CC=CC=C3	Ki = 136000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BO5ZR0	Chembl4227950	Investigative	145970445	C18H12BrNO2	354.2	C1=CC=C(C=C1)C2=NC(=CC(=C2)C3=CC=C(C=C3)Br)C(=O)O	Ki = 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BOEY56	2-Oxo-5-phenylsulfanyl-1H-pyridine-3-carbonitrile	Investigative	71575180	C12H8N2OS	228.27	C1=CC=C(C=C1)SC2=CNC(=O)C(=C2)C#N	IC50 = 82200 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BOS5G0	(R)-4-(4-(Dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide	Investigative	11502754	C18H24N4O4S2	424.5	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)N)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BOT9W7	3'-Amino-4-hydroxybiphenyl-3-carboxylic acid	Investigative	10955342	C13H11NO3	229.23	C1=CC(=CC(=C1)N)C2=CC(=C(C=C2)O)C(=O)O	IC50 = 190000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BPB24Q	4'-Hydroxy-4-methoxychalcone	Investigative	5355594	C16H14O3	254.28	COC1=CC=C(C=C1)/C=C/C(=O)C2=CC=C(C=C2)O	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BPBR38	4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitro-N-phenylbenzenesulfonamide	Investigative	57523430	C24H28N4O4S2	500.6	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC3=CC=CC=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BQ73RW	5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid	Investigative	14716643	C12H11NO2	201.22	C1CC2=CC=CC3=C2N(C1)C(=C3)C(=O)O	Ki = 131000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BQBO89	1-Hydroxy-4-(phenylsulfamoyl)naphthalene-2-carboxylic acid	Investigative	126480790	C17H13NO5S	343.4	C1=CC=C(C=C1)NS(=O)(=O)C2=CC(=C(C3=CC=CC=C32)O)C(=O)O	Ki = 106000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BQK30I	2-Hydroxy-5-(4-methylphenyl)benzoic Acid	Investigative	4613756	C14H12O3	228.24	CC1=CC=C(C=C1)C2=CC(=C(C=C2)O)C(=O)O	IC50 = 73000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BQR76E	3,6-Dichloro-1-benzothiophene-2-carboxylic acid	Investigative	739884	C9H4Cl2O2S	247.1	C1=CC2=C(C=C1Cl)SC(=C2Cl)C(=O)O	Ki = 59000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BR0P7H	3-Methyl-1-azatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraene-2-carboxylic acid	Investigative	84622107	C13H13NO2	215.25	CC1=C(N2CCCC3=C2C1=CC=C3)C(=O)O	Ki = 90000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BR3OJ0	4-(4-Chlorophenyl)-1-[(3s)-3,4-Dihydroxybutyl]-N-[3-(4-Methylpiperazin-1-Yl)propyl]-3-Phenyl-1h-Pyrrole-2-Carboxamide	Investigative	57339126	C29H37ClN4O3	525.1	CN1CCN(CC1)CCCNC(=O)C2=C(C(=CN2CC[C@@H](CO)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BR62LC	5-[4-(2-Methylbutan-2-yl)phenyl]sulfanyl-2-oxo-1H-pyridine-3-carbonitrile	Investigative	71575182	C17H18N2OS	298.4	CCC(C)(C)C1=CC=C(C=C1)SC2=CNC(=O)C(=C2)C#N	IC50 = 177500 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BR7DY8	(2S)-2-[(2S,3R)-3-Methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]carbamoyl]amino]methyl]-6-oxo-10-(2-phenylethylsulfonylamino)-3,4-dihydro-2H-1,5-benzoxazocin-5-yl]propanoic acid	Investigative	118723169	C32H35F3N4O7S	676.7	C[C@@H]1CN(C(=O)C2=C(C(=CC=C2)NS(=O)(=O)CCC3=CC=CC=C3)O[C@@H]1CN(C)C(=O)NC4=CC=C(C=C4)C(F)(F)F)[C@@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BRL16P	(2S)-2-[(2S,3R)-10-(Benzylsulfonylamino)-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]carbamoyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5-yl]propanoic acid	Investigative	118723168	C31H33F3N4O7S	662.7	C[C@@H]1CN(C(=O)C2=C(C(=CC=C2)NS(=O)(=O)CC3=CC=CC=C3)O[C@@H]1CN(C)C(=O)NC4=CC=C(C=C4)C(F)(F)F)[C@@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BRP6W0	5-Naphthalen-1-yl-2-oxo-1H-pyridine-3-carbonitrile	Investigative	71575178	C16H10N2O	246.26	C1=CC=C2C(=C1)C=CC=C2C3=CNC(=O)C(=C3)C#N	IC50 = 158500 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BRY9S5	2-((4-(4-Bromophenylsulfonamido)-1-methoxynaphthalen-2-yl)thio)acetamide	Investigative	71548703	C19H17BrN2O4S2	481.4	COC1=C(C=C(C2=CC=CC=C21)NS(=O)(=O)C3=CC=C(C=C3)Br)SCC(=O)N	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BS28ZJ	Methyl 2-((4-(4-bromophenylsulfonamido)-1-methoxynaphthalen-2-yl)thio)acetate	Investigative	71548999	C20H18BrNO5S2	496.4	COC1=C(C=C(C2=CC=CC=C21)NS(=O)(=O)C3=CC=C(C=C3)Br)SCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BS37CV	(2S)-2-[(2S,3R)-10-[(4-Fluorophenyl)sulfonylamino]-3-methyl-2-[[methyl-[[2-(trifluoromethyl)phenyl]carbamoyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5-yl]propanoic acid	Investigative	118723160	C30H30F4N4O7S	666.6	C[C@@H]1CN(C(=O)C2=C(C(=CC=C2)NS(=O)(=O)C3=CC=C(C=C3)F)O[C@@H]1CN(C)C(=O)NC4=CC=CC=C4C(F)(F)F)[C@@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BS5MH1	(2S)-2-[(4S)-4-[[4-(3-Methylphenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-N-(4-methylphenyl)sulfonyl-3-phenylpropanamide	Investigative	122194478	C33H31N3O5S	581.7	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)[C@H](CC2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=CC(=C5)C	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BSI80R	5-Bromo-1-methyl-1H-indole-2-carboxylic acid	Investigative	620146	C10H8BrNO2	254.08	CN1C2=C(C=C(C=C2)Br)C=C1C(=O)O	Ki = 81000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BT2Z3O	(2S)-2-[(2S,3R)-10-[(4-Fluorophenyl)sulfonylamino]-3-methyl-2-[[methyl(phenylcarbamoyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5-yl]propanoic acid	Investigative	118723161	C29H31FN4O7S	598.6	C[C@@H]1CN(C(=O)C2=C(C(=CC=C2)NS(=O)(=O)C3=CC=C(C=C3)F)O[C@@H]1CN(C)C(=O)NC4=CC=CC=C4)[C@@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BUFB14	(4-Chloro-3-methylphenoxy)acetic acid	Investigative	95696	C9H9ClO3	200.62	CC1=C(C=CC(=C1)OCC(=O)O)Cl	Ki = 103000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BUK3W1	4-Bromo-N-(3-butylsulfanyl-4-hydroxynaphthalen-1-yl)benzenesulfonamide	Investigative	71548855	C20H20BrNO3S2	466.4	CCCCSC1=C(C2=CC=CC=C2C(=C1)NS(=O)(=O)C3=CC=C(C=C3)Br)O	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BV1HC9	4-Bromo-N-[3-(4-hydroxybutyl)-4-methoxynaphthalen-1-yl]benzenesulfonamide	Investigative	71548852	C21H22BrNO4S	464.4	COC1=C(C=C(C2=CC=CC=C21)NS(=O)(=O)C3=CC=C(C=C3)Br)CCCCO	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BV2DT1	(E)-1-(2-Hydroxy-4-methoxyphenyl)-3-pyridin-4-ylprop-2-en-1-one	Investigative	5356316	C15H13NO3	255.27	COC1=CC(=C(C=C1)C(=O)/C=C/C2=CC=NC=C2)O	Ki ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BW0B4L	Chembl4208097	Investigative	145977960	C16H17NO4S	319.4	CC(C)C[C@@H](C(=O)O)N1C(=O)/C(=C/C2=CC=CC=C2)/SC1=O	Ki ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BW1J3Z	1-Methylindole-2-carboxylic acid	Investigative	27695	C10H9NO2	175.18	CN1C2=CC=CC=C2C=C1C(=O)O	Ki = 160000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BW3X2R	3-Chlorobenzo[b]thiophene-2-carboxylic acid	Investigative	307964	C9H5ClO2S	212.65	C1=CC=C2C(=C1)C(=C(S2)C(=O)O)Cl	Ki = 131000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BW7HD2	(2S)-2-[(2S,3R)-10-[(4-Fluorophenyl)sulfonylamino]-2-[[(4-methoxyphenyl)carbamoyl-methylamino]methyl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5-yl]propanoic acid	Investigative	118723162	C30H33FN4O8S	628.7	C[C@@H]1CN(C(=O)C2=C(C(=CC=C2)NS(=O)(=O)C3=CC=C(C=C3)F)O[C@@H]1CN(C)C(=O)NC4=CC=C(C=C4)OC)[C@@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BY95TF	2-[5-[(4-Bromophenyl)sulfonylamino]-2-hydroxyphenyl]sulfanylacetic acid	Investigative	89486940	C14H12BrNO5S2	418.3	C1=CC(=CC=C1S(=O)(=O)NC2=CC(=C(C=C2)O)SCC(=O)O)Br	IC50 ~ 100000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BYM01P	1-Hydroxy-4-[(4-propan-2-yloxyphenyl)sulfamoyl]naphthalene-2-carboxylic acid	Investigative	126480877	C20H19NO6S	401.4	CC(C)OC1=CC=C(C=C1)NS(=O)(=O)C2=CC(=C(C3=CC=CC=C32)O)C(=O)O	Ki = 54000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	BZ6J3N	4-Bromo-6-chloro-1-benzofuran-2-carboxylic acid	Investigative	71716750	C9H4BrClO3	275.48	C1=C(C=C(C2=C1OC(=C2)C(=O)O)Br)Cl	Ki = 90000 nM	Poor binder
T14912	Induced myeloid leukemia cell differentiation protein Mcl-1	D06VGD	ACENAPHTHOQUINONE	Investigative	6724	C12H6O2	182.17	C1=CC2=C3C(=C1)C(=O)C(=O)C3=CC=C2	Ki = 57000 nM	Poor binder