TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T14252	Gamma-aminobutyric acid transporter 4	B1GDX4	2,4-Dichloro-N-[1-[(4-iodophenyl)methyl]piperidin-4-yl]benzamide	Investigative	137639241	C19H19Cl2IN2O	489.2	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=C(C=C3)I	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B1GKJ7	1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic acid	Investigative	11743493	C27H29NO2S	431.6	C1CC(CN(C1)CCSC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)O	IC50 = 91000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B2OQ0Z	2,4-Dichloro-N-[1-[(2-nitrophenyl)methyl]piperidin-4-yl]benzamide	Investigative	137657292	C19H19Cl2N3O3	408.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B47YNW	1-{2-[(3-Fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl)-phenyl-methoxy]-ethyl}-piperidine-3-carboxylic acid	Investigative	9982662	C28H29F2NO4	481.5	COC1=C(C=C(C=C1)C(C2=CC=CC=C2)(C3=CC(=CC=C3)F)OCCN4CCCC(C4)C(=O)O)F	IC50 = 198000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B5EB1C	1-{2-[(4-Methoxy-phenyl)-diphenyl-methoxy]-ethyl}-piperidine-3-carboxylic acid	Investigative	10252950	C28H31NO4	445.5	COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCN4CCCC(C4)C(=O)O	IC50 = 178000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B5JF9L	(1s,2s,5r)-5-Aminobicyclo[3.1.0]hexane-2-carboxylic acid	Investigative	118711599	C7H11NO2	141.17	C1C[C@]2(C[C@H]2[C@H]1C(=O)O)N	IC50 = 76300 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B5JUH7	2,4-Dichloro-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]benzamide	Investigative	137638838	C23H22Cl2N2O	413.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC4=CC=CC=C4C=C3	IC50 ~ 50000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B5VY1Q	2,4-Dichloro-N-[1-[(2-cyanophenyl)methyl]piperidin-4-yl]benzamide	Investigative	137654858	C20H19Cl2N3O	388.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3C#N	IC50 ~ 50000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B67NTR	N-(1-Benzyl-4-piperidinyl)-1,3-benzodioxole-5-carboxamide	Investigative	9884272	C20H22N2O3	338.4	C1CN(CCC1NC(=O)C2=CC3=C(C=C2)OCO3)CC4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B6XF0Q	2,4-Dichloro-N-[1-[(E)-3-phenylprop-2-enyl]piperidin-4-yl]benzamide	Investigative	137638836	C21H22Cl2N2O	389.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)C/C=C/C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B7KA4R	(R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid	Investigative	6604883	C30H35NO6	505.6	COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)OCCN4CCC[C@H](C4)C(=O)O	IC50 = 86000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	B89XQC	Methyl 4-[[4-[(2,4-dichlorobenzoyl)amino]piperidin-1-yl]methyl]benzoate	Investigative	137642163	C21H22Cl2N2O3	421.3	COC(=O)C1=CC=C(C=C1)CN2CCC(CC2)NC(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BBFR86	1-{2-[Tris-(4-methoxy-phenyl)-methylsulfanyl]-ethyl}-piperidine-3-carboxylic acid	Investigative	10075407	C30H35NO5S	521.7	COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)SCCN4CCCC(C4)C(=O)O	IC50 = 142000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BGL58X	2,4-Dichloro-N-[1-[(4-cyanophenyl)methyl]piperidin-4-yl]benzamide	Investigative	137658990	C20H19Cl2N3O	388.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=C(C=C3)C#N	IC50 ~ 50000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BI4YL8	N-(1-Benzylpiperidin-4-yl)-2,4-dichlorobenzamide	Investigative	1069892	C19H20Cl2N2O	363.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BJ9W7E	1-{3-[Tris-(4-methoxy-phenyl)-methoxy]-propyl}-piperidine-3-carboxylic acid	Investigative	10052359	C31H37NO6	519.6	COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)OCCCN4CCCC(C4)C(=O)O	IC50 = 169000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BJHW74	2,4-Dichloro-N-(1-phenacylpiperidin-4-yl)benzamide	Investigative	137638617	C20H20Cl2N2O2	391.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BLOW98	(R,E)-1-(4-(2-Fluorophenyl)-4-o-tolylbut-3-enyl)piperidine-3-carboxylic acid	Investigative	50941729	C23H26FNO2	367.5	CC1=CC=CC=C1/C(=C\\CCN2CCC[C@H](C2)C(=O)O)/C3=CC=CC=C3F	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BO0UY4	1-[2-[9-(4-Methoxyphenyl)fluoren-9-yl]oxyethyl]piperidine-3-carboxylic Acid	Investigative	10072112	C28H29NO4	443.5	COC1=CC=C(C=C1)C2(C3=CC=CC=C3C4=CC=CC=C42)OCCN5CCCC(C5)C(=O)O	IC50 = 142000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BPA2B9	2,4-Dichloro-N-[1-(quinolin-2-ylmethyl)piperidin-4-yl]benzamide	Investigative	137659917	C22H21Cl2N3O	414.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=NC4=CC=CC=C4C=C3	IC50 ~ 50000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	BXG3Y0	2,4-Dichloro-N-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]benzamide	Investigative	137638595	C19H19Cl2N3O3	408.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	D0D2EF	(R)-nipecotic acid	Investigative	1796510	C6H11NO2	129.16	C1C[C@H](CNC1)C(=O)O	IC50 = 51000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	D0V5OY	N-(1-benzylpiperidine-4-yl)-2-naphthamide	Investigative	16725912	C23H24N2O	344.4	C1CN(CCC1NC(=O)C2=CC3=CC=CC=C3C=C2)CC4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T14252	Gamma-aminobutyric acid transporter 4	D0V7RG	4-substituted 2,4-dioxobutanoic acids	Investigative	3532	C6H9NO2	127.14	C1CNCC(=C1)C(=O)O	IC50 = 110000 nM	Poor binder