TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T13852	Sphingosine-1-phosphate receptor 1	B0QTB3	5-Cyclopropyl-N,N-bis(2-methylcyclohexyl)-1,2-oxazole-3-carboxamide	Investigative	25110496	C21H32N2O2	344.5	CC1CCCCC1N(C2CCCCC2C)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B1BW0S	4-Chloro-N-[1-(2,3-dimethylimidazol-4-yl)-2-phenylethyl]benzenesulfonamide	Investigative	118729161	C19H20ClN3O2S	389.9	CC1=NC=C(N1C)C(CC2=CC=CC=C2)NS(=O)(=O)C3=CC=C(C=C3)Cl	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B27HCT	N-Cyclohexyl-5-cyclopropylisoxazole-3-carboxamide	Investigative	16188020	C13H18N2O2	234.29	C1CCC(CC1)NC(=O)C2=NOC(=C2)C3CC3	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B3PI0A	N,N-Dicyclohexyl-5-cyclopentyl-1,2-oxazole-3-carboxamide	Investigative	56955982	C21H32N2O2	344.5	C1CCC(CC1)N(C2CCCCC2)C(=O)C3=NOC(=C3)C4CCCC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B4P9QV	N-Cyclohexyl-5-cyclopropyl-N-(oxan-4-yl)-1,2-oxazole-3-carboxamide	Investigative	25110500	C18H26N2O3	318.4	C1CCC(CC1)N(C2CCOCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B4W5RX	4-[2-[4-[(2-Chlorophenyl)methoxy]phenyl]ethyl]-2-oxo-1,3-oxazolidine-4-carboxamide	Investigative	57403950	C19H19ClN2O4	374.8	C1C(NC(=O)O1)(CCC2=CC=C(C=C2)OCC3=CC=CC=C3Cl)C(=O)N	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B5HMI7	5-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]pentanoic acid	Investigative	134130884	C24H23NO2S	389.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCCCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B5R8PM	N-Cyclopentyl-5-cyclopropyl-N-(2-methylcyclohexyl)-1,2-oxazole-3-carboxamide	Investigative	25110510	C19H28N2O2	316.4	CC1CCCCC1N(C2CCCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B8C2JN	1-[(5-Naphthalen-2-yl-1-benzothiophen-2-yl)methyl]azetidine-3-carboxylic acid	Investigative	134130169	C23H19NO2S	373.5	C1C(CN1CC2=CC3=C(S2)C=CC(=C3)C4=CC5=CC=CC=C5C=C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	B9P8DB	2-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]acetic acid	Investigative	134130695	C21H17NO2S	347.4	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCC(=O)O	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BC81HS	N-Cyclohexyl-N-cyclopentyl-5-cyclopropyl-1,2-oxazole-3-carboxamide	Investigative	25110492	C18H26N2O2	302.4	C1CCC(CC1)N(C2CCCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BDP9E8	N-Cyclohexyl-N-(cyclohexylmethyl)-5-cyclopropyl-1,2-oxazole-3-carboxamide	Investigative	25110494	C20H30N2O2	330.5	C1CCC(CC1)CN(C2CCCCC2)C(=O)C3=NOC(=C3)C4CC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BE8PY2	4-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]butanoic acid	Investigative	134131381	C23H21NO2S	375.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BG9M4T	N,N-Dicyclohexyl-5-methylisoxazole-3-carboxamide	Investigative	3245758	C17H26N2O2	290.4	CC1=CC(=NO1)C(=O)N(C2CCCCC2)C3CCCCC3	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BIWV59	N-[1-(4-Benzyl-5-methyl-1,2,4-triazol-3-yl)-2-phenylethyl]-4-chlorobenzenesulfonamide	Investigative	118729156	C24H23ClN4O2S	467	CC1=NN=C(N1CC2=CC=CC=C2)C(CC3=CC=CC=C3)NS(=O)(=O)C4=CC=C(C=C4)Cl	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BP64OR	N-Benzyl-5-cyclopropyl-N-pyridin-2-yl-1,2-oxazole-3-carboxamide	Investigative	25110212	C19H17N3O2	319.4	C1CC1C2=CC(=NO2)C(=O)N(CC3=CC=CC=C3)C4=CC=CC=N4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BQ43ZB	3-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]propanoic acid	Investigative	134130546	C22H19NO2S	361.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BR5K2G	US9187437, 42 (comparative)	Investigative	89707709	C20H20N2O	304.4	C1CCC(C(C1)C2=CC=CC=C2)C3=NC(=NO3)C4=CC=CC=C4	EC50 ~ 62000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BTP8G2	4-[[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid	Investigative	134130548	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCC5=CC=C(C=C5)C(=O)O	EC50 ~ 100000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BV69NL	N,N,5-Tricyclohexyl-1,2-oxazole-3-carboxamide	Investigative	56955980	C22H34N2O2	358.5	C1CCC(CC1)C2=CC(=NO2)C(=O)N(C3CCCCC3)C4CCCCC4	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BVWK65	N-Cyclohexyl-5-propyl-3-isoxazolecarboxamide	Investigative	5307570	C13H20N2O2	236.31	CCCC1=CC(=NO1)C(=O)NC2CCCCC2	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BWHI48	N-Cyclohexyl-N-phenyl-5-propyl-1,2-oxazole-3-carboxamide	Investigative	25110105	C19H24N2O2	312.4	CCCC1=CC(=NO1)C(=O)N(C2CCCCC2)C3=CC=CC=C3	EC50 ~ 50000 nM	Poor binder
T13852	Sphingosine-1-phosphate receptor 1	BZ6EI1	4-({[7-(Naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	Investigative	124221654	C23H21NO2S	375.5	C1=CC=C2C=C(C=CC2=C1)C3=CC=CC4=C3SC(=C4)CNCCCC(=O)O	EC50 ~ 100000 nM	Poor binder