TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	D0R9OH	Sulfamethoxazole	Approved	5329	C10H11N3O3S	253.28	CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N	IC50 ~ 57000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	B2H9QG	(2S,3S,4S,5R)-5-((3,4-Dichlorobenzylamino)methyl)-N-cycloheptyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide	Investigative	44585248	C20H28Cl2N2O4	431.3	C1CCCC(CC1)NC(=O)[C@@H]2[C@H]([C@@H]([C@H](O2)CNCC3=CC(=C(C=C3)Cl)Cl)O)O	IC50 = 80000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	B8QM0S	Ethyl 3-[[4-[[2-(3,4-dichlorophenyl)acetyl]amino]phenyl]sulfonylamino]benzoate	Investigative	53255416	C23H20Cl2N2O5S	507.4	CCOC(=O)C1=CC(=CC=C1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)CC3=CC(=C(C=C3)Cl)Cl	IC50 ~ 57000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	BA9OS5	3-O-Acetylgreenwayodendrin	Investigative	46891355	C25H33NO2	379.5	CC(=O)O[C@H]1CC[C@]2([C@H](C1(C)C)CC[C@@]3([C@@H]2CC4=CC5=CC=CC=C5N43)C)C	IC50 = 170000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	BC61BT	(2S,3S,4S,5R)-5-((3,4-Dichlorobenzylamino)methyl)-N-allyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide	Investigative	44585245	C16H20Cl2N2O4	375.2	C=CCNC(=O)[C@@H]1[C@H]([C@@H]([C@H](O1)CNCC2=CC(=C(C=C2)Cl)Cl)O)O	IC50 = 50000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	BJW76S	2-(4-Methoxy-3-methylphenyl)-N-[4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]acetamide	Investigative	53255406	C20H21N3O5S	415.5	CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)CC3=CC(=C(C=C3)OC)C	IC50 ~ 57000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	BL59NZ	4-[[2-(3,4-Dichlorophenyl)acetyl]amino]-N-(5-methyl-1,2-oxazol-3-yl)benzamide	Investigative	53255391	C19H15Cl2N3O3	404.2	CC1=CC(=NO1)NC(=O)C2=CC=C(C=C2)NC(=O)CC3=CC(=C(C=C3)Cl)Cl	IC50 ~ 57000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	BN3V1G	2-[[2-(3,4-Dichlorophenyl)acetyl]amino]-N-(5-methyl-1,2-oxazol-3-yl)-1,3-thiazole-4-carboxamide	Investigative	53255422	C16H12Cl2N4O3S	411.3	CC1=CC(=NO1)NC(=O)C2=CSC(=N2)NC(=O)CC3=CC(=C(C=C3)Cl)Cl	IC50 ~ 57000 nM	Poor binder
T08280	Trypanosoma Pyrophosphate-dependent phosphofructokinase	BQMV34	2-(3,4-Dimethoxyphenyl)-N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}acetamide	Investigative	2434603	C20H21N3O6S	431.5	CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)CC3=CC(=C(C=C3)OC)OC	IC50 ~ 57000 nM	Poor binder