TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T06773	Hypoxia-inducible factor 1 alpha	B0KE7W	3-[[4-(3-Phenylureido)phenyl]aminomethyl]phenol	Investigative	54580396	C20H19N3O2	333.4	C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)NCC3=CC(=CC=C3)O	IC50 = 69900 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	B1Q7TN	3-(2-(4-Ethylphenoxy)acetamido)-4-hydroxyphenylboronic acid	Investigative	46232965	C16H18BNO5	315.1	B(C1=CC(=C(C=C1)O)NC(=O)COC2=CC=C(C=C2)CC)(O)O	IC50 ~ 100000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	B4GW3S	2-(4-Cyclohexylphenoxy)-N-(2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide	Investigative	46232962	C26H34BNO5	451.4	B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(C=C2)O)NC(=O)COC3=CC=C(C=C3)C4CCCCC4	IC50 = 70400 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	B5OHM8	N-(2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-(p-tolyloxy)acetamide	Investigative	46232841	C21H26BNO5	383.2	B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(C=C2)O)NC(=O)COC3=CC=C(C=C3)C	IC50 = 90600 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	B7NI2B	1-[4-(3-Methoxy-benzylamino)phenyl]-3-phenylurea	Investigative	54586265	C21H21N3O2	347.4	COC1=CC=CC(=C1)CNC2=CC=C(C=C2)NC(=O)NC3=CC=CC=C3	IC50 = 52100 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	B89VFB	3-(2-(Biphenyl-4-yloxy)acetamido)-4-hydroxyphenylboronic acid	Investigative	46233004	C20H18BNO5	363.2	B(C1=CC(=C(C=C1)O)NC(=O)COC2=CC=C(C=C2)C3=CC=CC=C3)(O)O	IC50 ~ 100000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	B96DYE	2-(Biphenyl-4-yloxy)-N-(2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide	Investigative	46232961	C26H28BNO5	445.3	B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(C=C2)O)NC(=O)COC3=CC=C(C=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BA3FX7	Ethyl 5-[(4-chlorophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate	Investigative	127048857	C18H16ClNO5S	393.8	CCOC(=O)C1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)Cl)C	IC50 = 50000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BB1JE0	2-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic acid	Investigative	54581400	C21H19N3O3	361.4	C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)NCC3=CC=CC=C3C(=O)O	IC50 = 51700 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BBJ75S	4-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic acid	Investigative	54587290	C21H19N3O3	361.4	C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)NCC3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BG04YP	4-Hydroxy-3-(2-(p-tolyloxy)acetamido)phenylboronic acid	Investigative	46232964	C15H16BNO5	301.1	B(C1=CC(=C(C=C1)O)NC(=O)COC2=CC=C(C=C2)C)(O)O	IC50 ~ 100000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BO2Q7Y	3-(2-(4-Cyclohexylphenoxy)acetamido)-4-hydroxyphenylboronic acid	Investigative	46233005	C20H24BNO5	369.2	B(C1=CC(=C(C=C1)O)NC(=O)COC2=CC=C(C=C2)C3CCCCC3)(O)O	IC50 = 84800 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BPV8G7	(3S)-2'-Bromo-5'-[[(3S)-4'-bromo-8-hydroxy-3'-oxospiro[6,10,15-triazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(15),2(7),8,10,12(16)-pentaene-3,6'-cyclohexa-1,4-diene]-1'-yl]disulfanyl]-8-hydroxyspiro[6,10,15-triazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(15),2(7),8,10,12(16)-pentaene-3,4'-cyclohexa-2,5-diene]-1'-one	Investigative	136721264	C36H26Br2N6O4S2	830.6	C1CN=C2C3=C1C=NC3=C(C4=C2[C@]5(CCN4)C=C(C(=O)C=C5SSC6=CC(=O)C(=C[C@]67CCNC8=C7C9=NCCC1=C9C(=C8O)N=C1)Br)Br)O	IC50 ~ 100000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BUF58E	2-(4-Ethylphenoxy)-N-(2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide	Investigative	46232842	C22H28BNO5	397.3	B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(C=C2)O)NC(=O)COC3=CC=C(C=C3)CC	IC50 = 91800 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BWDV57	Moracin M	Investigative	185848	C14H10O4	242.23	C1=CC2=C(C=C1O)OC(=C2)C3=CC(=CC(=C3)O)O	IC50 ~ 50000 nM	Poor binder
T06773	Hypoxia-inducible factor 1 alpha	BYW03H	1-[4-[4-(Methoxycarbonyl)benzylamino]phenyl]-3-phenylurea	Investigative	54580397	C22H21N3O3	375.4	COC(=O)C1=CC=C(C=C1)CNC2=CC=C(C=C2)NC(=O)NC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder