TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T04507	Presynaptic density protein 95	B0RP8U	(2S)-2-[[(2S)-3-Carboxy-2-[[(2S,3R)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349724	C18H31N5O9	461.5	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)N)N)O	Ki = 60000 nM	Poor binder
T04507	Presynaptic density protein 95	B1IU6O	(S)-4-Amino-5-((S)-1-((S)-5-amino-1-((S)-1-carboxy-2-methylpropylamino)-1,5-dioxopentan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44568998	C18H31N5O9	461.5	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)N	Ki = 57000 nM	Poor binder
T04507	Presynaptic density protein 95	B2I3ML	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2,5-Diamino-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349723	C17H31N5O7	417.5	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)N)N)O	Ki = 110000 nM	Poor binder
T04507	Presynaptic density protein 95	B3KM2O	(4S)-4-(Benzylamino)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid	Investigative	25133945	C24H36N4O8	508.6	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NCC1=CC=CC=C1)O	Ki = 63000 nM	Poor binder
T04507	Presynaptic density protein 95	B40VTX	(4S)-4-(3-Anthracen-9-ylpropylamino)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid	Investigative	51350401	C34H44N4O8	636.7	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NCCCC1=C2C=CC=CC2=CC3=CC=CC=C31)O	Ki = 95000 nM	Poor binder
T04507	Presynaptic density protein 95	B4ET0G	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-Amino-2-(2-cyclohexylethylamino)-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349855	C25H45N5O7	527.7	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NCCC1CCCCC1)O	Ki = 141000 nM	Poor binder
T04507	Presynaptic density protein 95	B4KC6F	(S)-4-Amino-5-((S)-1-((S)-4-amino-1-((S)-1-carboxy-2-methylpropylamino)-1,4-dioxobutan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44569003	C17H29N5O9	447.4	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)N	Ki = 67000 nM	Poor binder
T04507	Presynaptic density protein 95	B57QDM	(4S)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-Carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxo-4-(2-pyren-1-ylethylamino)pentanoic acid	Investigative	51350402	C35H42N4O8	646.7	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NCCC1=C2C=CC3=CC=CC4=C3C2=C(C=C4)C=C1)O	Ki = 51000 nM	Poor binder
T04507	Presynaptic density protein 95	B5V9WB	(4S)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-Carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-(3-naphthalen-2-ylpropylamino)-5-oxopentanoic acid	Investigative	51350268	C30H42N4O8	586.7	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NCCCC1=CC2=CC=CC=C2C=C1)O	Ki = 53000 nM	Poor binder
T04507	Presynaptic density protein 95	B6NW3G	Thr-Ala-Val	Investigative	127046244	C12H23N3O5	289.33	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)N)O	Ki = 74000 nM	Poor binder
T04507	Presynaptic density protein 95	B7G2FU	(2S)-2-[[(2S)-2-[[(2S,3R)-3-Hydroxy-2-[[(2S)-2-(2-naphthalen-2-ylethylamino)propanoyl]amino]butanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349988	C27H38N4O6	514.6	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](C)NCCC1=CC2=CC=CC=C2C=C1)O	Ki = 56000 nM	Poor binder
T04507	Presynaptic density protein 95	B8D6QH	(4S)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-Carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxo-4-(4-pyren-1-ylbutylamino)pentanoic acid	Investigative	51350403	C37H46N4O8	674.8	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NCCCCC1=C2C=CC3=CC=CC4=C3C2=C(C=C4)C=C1)O	Ki = 76000 nM	Poor binder
T04507	Presynaptic density protein 95	BC4YX6	(S)-4-Amino-5-((S)-1-((S)-3-carboxy-1-((S)-1-carboxy-2,2-dimethylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44568997	C18H30N4O10	462.5	CC(C)(C)[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)N	Ki = 76000 nM	Poor binder
T04507	Presynaptic density protein 95	BE42XR	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(2-Cyclohexylethylamino)propanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349857	C23H42N4O6	470.6	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](C)NCCC1CCCCC1)O	Ki = 89000 nM	Poor binder
T04507	Presynaptic density protein 95	BH4ZW7	(4S)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-Carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-(ethylamino)-5-oxopentanoic acid	Investigative	25133601	C19H34N4O8	446.5	CCN[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O	Ki = 69000 nM	Poor binder
T04507	Presynaptic density protein 95	BJD31T	(S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carboxy-butyrylamino)-3-hydroxy-propionylamino]-4-carboxy-butyrylamino}-3-methyl-butyric acid	Investigative	25062887	C18H30N4O10	462.5	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)N	Ki = 67000 nM	Poor binder
T04507	Presynaptic density protein 95	BK0U9E	(S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carbamoyl-butyrylamino)-3-hydroxy-propionylamino]-3-carboxy-propionylamino}-3-methyl-butyric acid	Investigative	44568787	C17H29N5O9	447.4	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N)N	Ki = 100000 nM	Poor binder
T04507	Presynaptic density protein 95	BNJ40C	(4S)-5-[[(2S,3R)-1-[[(2S)-1-[[(1S)-1-Carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-(methylamino)-5-oxopentanoic acid	Investigative	25133600	C18H32N4O8	432.5	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC)O	Ki = 78000 nM	Poor binder
T04507	Presynaptic density protein 95	BOM98Q	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-Aminopropanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349725	C15H28N4O6	360.41	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](C)N)O	Ki = 73000 nM	Poor binder
T04507	Presynaptic density protein 95	BUQ92F	(4S)-4-Amino-5-[[(2S)-1-[[(2S)-3-carboxy-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Investigative	25062886	C17H28N4O10	448.4	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)N	Ki = 56000 nM	Poor binder
T04507	Presynaptic density protein 95	BV31WA	(S)-4-Amino-5-((S)-1-(((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-yl)(methyl)amino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44568990	C18H30N4O10	462.5	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)N	Ki = 78000 nM	Poor binder
T04507	Presynaptic density protein 95	BYRW64	(4S)-5-[[(2S,3R)-1-[[(2S)-3-Carboxy-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-[2-(3,4-dichlorophenyl)ethylamino]-5-oxopentanoic acid	Investigative	51349987	C26H36Cl2N4O10	635.5	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NCCC1=CC(=C(C=C1)Cl)Cl)O	Ki = 130000 nM	Poor binder
T04507	Presynaptic density protein 95	BZ4TC2	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[2-(3,4-Dichlorophenyl)ethylamino]propanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid	Investigative	51349989	C23H34Cl2N4O6	533.4	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](C)NCCC1=CC(=C(C=C1)Cl)Cl)O	Ki = 64000 nM	Poor binder