TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T03687	Histone deacetylase 9	D0E7PQ	Vorinostat	Approved	5311	C14H20N2O3	264.32	C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO	IC50 = 80030 nM	Poor binder
T03687	Histone deacetylase 9	D0L7LC	Romidepsin	Approved	5352062	C24H36N4O6S2	540.7	C/C=C\\1/C(=O)N[C@H](C(=O)O[C@H]\\2CC(=O)N[C@@H](C(=O)N[C@H](CSSCC/C=C2)C(=O)N1)C(C)C)C(C)C	IC50 ~ 50000 nM	Poor binder
T03687	Histone deacetylase 9	D0M8FD	SNDX-275	Phase 2	4261	C21H20N4O3	376.4	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B03PZD	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide	Investigative	136025984	C19H25N3O2S	359.5	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B0GAH1	Pimelic Diphenylamide 106	Investigative	16070100	C20H25N3O2	339.4	CC1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B0R4TM	2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one	Investigative	135497781	C17H20N2O2S	316.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B0VTQ6	N-(2-Aminophenyl)-7,7-di(1H-indol-3-yl)heptanamide	Investigative	45271073	C29H30N4O	450.6	C1=CC=C2C(=C1)C(=CN2)C(CCCCCC(=O)NC3=CC=CC=C3N)C4=CNC5=CC=CC=C54	IC50 = 50000 nM	Poor binder
T03687	Histone deacetylase 9	B13SGM	(2E,4E)-5-[4-[3-(1-Adamantyl)-4-methoxyphenyl]phenyl]-N-hydroxypenta-2,4-dienamide	Investigative	90654947	C28H31NO3	429.5	COC1=C(C=C(C=C1)C2=CC=C(C=C2)/C=C/C=C/C(=O)NO)C34CC5CC(C3)CC(C5)C4	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B1SXO5	N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56659403	C15H15N3O2S	301.4	CC1=NC(=NC=C1)SCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B1TSK2	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[4-(propylaminocarbamoyl)anilino]propan-2-yl]-4-methoxybenzamide	Investigative	137635119	C29H31N5O4	513.6	CCCNNC(=O)C1=CC=C(C=C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T03687	Histone deacetylase 9	B2VLJ6	N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide	Investigative	136025842	C14H15N3O2S	289.35	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B3TCW8	N-Hydroxy-2-propylpentanamide	Investigative	88129	C8H17NO2	159.23	CCCC(CCC)C(=O)NO	IC50 = 91000 nM	Poor binder
T03687	Histone deacetylase 9	B4ZEY0	Thailandepsin B	Investigative	56676500	C24H39N3O6S2	529.7	CCCC[C@@H]1C(=O)N[C@@H]2CSSCC/C=C/[C@H](CC(=O)N1)OC(=O)C[C@@H]([C@H](NC2=O)[C@@H](C)CC)O	IC50 ~ 50000 nM	Poor binder
T03687	Histone deacetylase 9	B51YIG	Propan-2-Yl N-[(2s,4r)-1-Ethanoyl-2-Methyl-6-[4-(Methylaminomethyl)phenyl]-3,4-Dihydro-2h-Quinolin-4-Yl]carbamate	Investigative	52912223	C24H31N3O3	409.5	C[C@H]1C[C@H](C2=C(N1C(=O)C)C=CC(=C2)C3=CC=C(C=C3)CNC)NC(=O)OC(C)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B5HIZ3	N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	56673261	C16H16N2O4	300.31	CC1=CC(=O)NC(=C1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B6VBR2	S-[(E)-4-[(9S,12S)-7,10,14-Trioxo-9-propan-2-yl-11-oxa-18-thia-3,4,5,8,15,20,21-heptazatricyclo[15.2.1.12,5]henicosa-1(19),2(21),3,17(20)-tetraen-12-yl]but-3-enyl] octanethioate	Investigative	71540745	C27H39N7O5S2	605.8	CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCC2=NC(=CS2)C3=NN(CC(=O)N[C@H](C(=O)O1)C(C)C)N=N3	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B75BOR	N-(4-(2-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)acetyl)phenyl)acetamide	Investigative	135446479	C15H15N3O3S	317.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 = 74100 nM	Poor binder
T03687	Histone deacetylase 9	B76NHE	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide	Investigative	136086923	C17H21N3O2S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B7JEZ8	1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one	Investigative	135462117	C8H10N2O2S	198.24	CC1=CC(=O)NC(=N1)SCC(=O)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B81YTQ	N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide	Investigative	56666337	C16H15NO3S	301.4	CC(=O)NC1=CC=C(C=C1)C(=O)CSC2=CC=CC(=C2)O	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	B93MKY	N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide	Investigative	136025843	C15H17N3O3S	319.4	CC1=CC(=O)NC(=N1)SCC(C2=CC=C(C=C2)NC(=O)C)O	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BAL2D3	5-[[6-Oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanehydroxamic acid	Investigative	136173089	C21H21N3O3S	395.5	C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC(=O)NC(=N3)SCCCCC(=O)NO	IC50 ~ 50000 nM	Poor binder
T03687	Histone deacetylase 9	BC05YB	E,E-5-(4''-Methoxybiphenyl-4-yl)-penta-2,4-dienoic acid Nhydroxyamide	Investigative	42631047	C18H17NO3	295.3	COC1=CC=C(C=C1)C2=CC=C(C=C2)/C=C/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BC54SO	2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	136086920	C15H14N2O4S	318.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(C=C2)OCCO3	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BCF9O6	N-Hydroxy-5-(1-phenylpyrazol-3-yl)pentanamide	Investigative	118714371	C14H17N3O2	259.3	C1=CC=C(C=C1)N2C=CC(=N2)CCCCC(=O)NO	IC50 = 55800 nM	Poor binder
T03687	Histone deacetylase 9	BDCZ86	2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide	Investigative	135441620	C15H17N3O2S	303.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BFC08Z	2-[2-(4-Hydroxyphenyl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	135928628	C13H12N2O3S	276.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)O	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BG09QH	N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide	Investigative	1108280	C16H17N3O2S	315.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BHGX52	6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-one	Investigative	135412194	C13H12N2O2S	260.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BI6ZB1	N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide	Investigative	136025986	C16H17N3O3S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)N(C)C(=O)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BJ1OD3	2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135473106	C11H16N2O2S	240.32	CC1=CC(=O)NC(=N1)SCC(=O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BJ2Y3N	2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135437514	C13H11ClN2O2S	294.76	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)Cl	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BL5RX8	2-[5-(3-Nitrophenyl)furfuryl]-1,2,3,4-tetrahydroisoquinoline-7-carbohydroximic acid	Investigative	101882265	C21H19N3O5	393.4	C1CN(CC2=C1C=CC(=C2)C(=O)NO)CC3=CC=C(O3)C4=CC(=CC=C4)[N+](=O)[O-]	IC50 = 65800 nM	Poor binder
T03687	Histone deacetylase 9	BLBA30	2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone	Investigative	135449197	C14H14N2O3S	290.34	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BO3G4S	(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]propanoic acid	Investigative	86294741	C9H10N2O4S	242.25	C[C@H](C(=O)O)NC(=O)C1=CC=CC(=S)N1O	IC50 = 58000 nM	Poor binder
T03687	Histone deacetylase 9	BPRY15	Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate	Investigative	135412048	C8H10N2O3S	214.24	CC1=CC(=O)NC(=N1)SCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BRGV98	1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanone	Investigative	135444536	C13H12N2O4S	292.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BRH7M9	N-(2-Aminophenyl)-4-[[[(4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-ylidene]amino]methyl]benzamide	Investigative	136110961	C29H26N4O2	462.5	C1=CC=C(C=C1)[C@@H]2[C@@H](OC(=NCC3=CC=C(C=C3)C(=O)NC4=CC=CC=C4N)N2)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BVN3K5	S-[(E)-4-[(9S,12S)-7,10,14-Trioxo-9-propan-2-yl-11-oxa-18-thia-3,4,5,8,15,20-hexazatricyclo[15.2.1.12,5]henicosa-1(19),2(21),3,17(20)-tetraen-12-yl]but-3-enyl] octanethioate	Investigative	71540743	C28H40N6O5S2	604.8	CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCC2=NC(=CS2)C3=CN(CC(=O)N[C@H](C(=O)O1)C(C)C)N=N3	IC50 = 63200 nM	Poor binder
T03687	Histone deacetylase 9	BVSP75	6-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]-1,3-dihydroindol-2-one	Investigative	136086921	C15H13N3O3S	315.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(CC(=O)N3)C=C2	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BW53QM	N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56673234	C16H17N3O3S	331.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)OC	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BX18GK	Ethyl 4-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-3-oxobutanoate	Investigative	136086922	C11H14N2O4S	270.31	CCOC(=O)CC(=O)CSC1=NC(=CC(=O)N1)C	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BX62ZD	6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-one	Investigative	135407493	C11H10N2O2S2	266.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CS2	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BX8AF0	N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]benzamide	Investigative	136025837	C20H17N3O3S	379.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T03687	Histone deacetylase 9	BXK72U	Thailandepsin A	Investigative	56602459	C23H37N3O6S3	547.8	CC[C@H](C)[C@@H]1[C@H](CC(=O)O[C@H]\\2CC(=O)N[C@@H](C(=O)N[C@H](CSSCC/C=C2)C(=O)N1)CCSC)O	IC50 ~ 50000 nM	Poor binder
T03687	Histone deacetylase 9	BY0P1V	Propan-2-yl N-[(2S,4R)-1-acetyl-6-[[8-(hydroxyamino)-8-oxooctanoyl]amino]-2-methyl-3,4-dihydro-2H-quinolin-4-yl]carbamate	Investigative	90667453	C24H36N4O6	476.6	C[C@H]1C[C@H](C2=C(N1C(=O)C)C=CC(=C2)NC(=O)CCCCCCC(=O)NO)NC(=O)OC(C)C	IC50 = 61660 nM	Poor binder