TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B03KWQ	(R)-(5-Ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)-(6-methoxy-2-thiophen-3-yl-quinolin-4-yl)-methanol	Investigative	44323339	C24H28N2O2S	408.6	CCC1CN2CCC1CC2[C@@H](C3=CC(=NC4=C3C=C(C=C4)OC)C5=CSC=C5)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B1S6EM	(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-[[(2R)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Investigative	44273516	C54H78N12O18	1183.3	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B2AV5T	(2R)-6-Amino-2-[[(2S)-3-(4-amino-3,5-dibromophenyl)-2-(4-phenylbutanoylamino)propanoyl]amino]-N-phenylhexanamide	Investigative	44403914	C31H37Br2N5O3	687.5	C1=CC=C(C=C1)CCCC(=O)N[C@@H](CC2=CC(=C(C(=C2)Br)N)Br)C(=O)N[C@H](CCCCN)C(=O)NC3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B2MCR8	Yvptnvgsegf	Investigative	44273364	C53H76N12O18	1169.2	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)O	IC50 = 51000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B3SQ1O	(2R)-6-Amino-2-[[(2S)-3-(4-amino-3,5-dibromophenyl)-2-(3-phenylpropanoylamino)propanoyl]amino]-N-(2-phenylethyl)hexanamide	Investigative	44403918	C32H39Br2N5O3	701.5	C1=CC=C(C=C1)CCC(=O)N[C@@H](CC2=CC(=C(C(=C2)Br)N)Br)C(=O)N[C@H](CCCCN)C(=O)NCCC3=CC=CC=C3	IC50 = 196000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B43CFH	Yvptqvgseaf	Investigative	44273609	C55H80N12O18	1197.3	C[C@H]([C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)O	IC50 = 95000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B5DF1E	(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2R)-4-Amino-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Investigative	44274076	C54H78N12O18	1183.3	C[C@H]([C@@H](C(=O)N[C@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	B5UE2O	(4S)-4-[[(2R)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Investigative	44274074	C54H78N12O18	1183.3	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BCX9W0	Yvpsnvgseaf	Investigative	44273843	C53H76N12O18	1169.2	C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BK9RS5	(R)-(5-Ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)-[6-methoxy-2-(4-methoxy-phenyl)-quinolin-4-yl]-methanol	Investigative	44323086	C27H32N2O3	432.6	CCC1CN2CCC1CC2[C@@H](C3=CC(=NC4=C3C=C(C=C4)OC)C5=CC=C(C=C5)OC)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BM2RG9	(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Investigative	44273992	C54H78N12O18	1183.3	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@@H](CC3=CC=C(C=C3)O)N)O	IC50 = 80000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BS1ON5	(R)-[2-(3-Amino-phenyl)-6-methoxy-quinolin-4-yl]-(5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol	Investigative	44323087	C26H31N3O2	417.5	CCC1CN2CCC1CC2[C@@H](C3=CC(=NC4=C3C=C(C=C4)OC)C5=CC(=CC=C5)N)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BT14KE	(R)-(5-Ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)-(6-methoxy-2-phenyl-quinolin-4-yl)-methanol	Investigative	44323110	C26H30N2O2	402.5	CCC1CN2CCC1CC2[C@@H](C3=CC(=NC4=C3C=C(C=C4)OC)C5=CC=CC=C5)O	IC50 = 96000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BUTS02	Yvptavgseaf	Investigative	44273969	C53H77N11O17	1140.2	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)O	IC50 ~ 100000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BV8ZJ1	Yvptfvgseaf	Investigative	44273362	C59H81N11O17	1216.3	C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)N)O	IC50 = 70000 nM	Poor binder
T02226	HUMAN calcitonin gene-related peptide type 1 receptor	BYR2K8	(R)-(2-Benzo[1,3]dioxol-5-yl-6-methoxy-quinolin-4-yl)-(5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol	Investigative	44323341	C27H30N2O4	446.5	CCC1CN2CCC1CC2[C@@H](C3=CC(=NC4=C3C=C(C=C4)OC)C5=CC6=C(C=C5)OCO6)O	IC50 = 74000 nM	Poor binder