TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	D06IAR	Adenosine	Approved	60961	C10H13N5O4	267.24	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N	Ki ~ 100000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	B27GIR	Adenosine 5''-methylenebis(sulfonamide)	Investigative	44578789	C11H17N7O7S2	423.4	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CNS(=O)(=O)CS(=O)(=O)N)O)O)N	Ki ~ 100000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	B2RFN4	(E)-3-[4-[[(4-Cyano-3-methoxyphenyl)carbamoylamino]methyl]phenyl]-N-hydroxyprop-2-enamide	Investigative	25181867	C19H18N4O4	366.4	COC1=C(C=CC(=C1)NC(=O)NCC2=CC=C(C=C2)/C=C/C(=O)NO)C#N	Ki ~ 100000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	B4C3LG	N-(4-Chlorophenyl)-2-phenoxypropanamide	Investigative	3140491	C15H14ClNO2	275.73	CC(C(=O)NC1=CC=C(C=C1)Cl)OC2=CC=CC=C2	EC50 ~ 50000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	B9BN1T	2-[5-O-[(5'-Adenylyloxy)phosphonyl]-beta-D-ribofuranosyl]-4-carbamoylfuran	Investigative	10841975	C20H26N6O15P2	652.4	C1=C(OC=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O	Ki = 135120 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	BNB62G	6-(2,4-Dimethoxy-3-methyl-5-(oxazol-5-yl)phenyl)-4-methylhex-4-enoic acid	Investigative	44589785	C19H23NO5	345.4	CC1=C(C(=CC(=C1OC)C2=CN=CO2)C/C=C(\\C)/CCC(=O)O)OC	Ki ~ 100000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	BRT6X9	(4E)-6-(4,6-Dimethoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid	Investigative	44433349	C18H22O6	334.4	CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\\C)/CCC(=O)O)OC	IC50 = 67000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	BU6AS5	N-(4-Methoxyphenyl)-2-(2-thiazol-4-ylbenzimidazol-1-yl)acetamide	Investigative	6618978	C19H16N4O2S	364.4	COC1=CC=C(C=C1)NC(=O)CN2C3=CC=CC=C3N=C2C4=CSC=N4	IC50 ~ 50000 nM	Poor binder
T02024	HUMAN inosine-5'-monophosphate dehydrogenase 1	BW40DV	(Z)-6-(2,4-Dimethoxy-5-(oxazol-5-yl)phenyl)-4-methylhex-4-enoic acid	Investigative	44589786	C18H21NO5	331.4	C/C(=C/CC1=CC(=C(C=C1OC)OC)C2=CN=CO2)/CCC(=O)O	Ki = 97300 nM	Poor binder