TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T01943 Plasmodium Beta-hydroxyacyl-ACP dehydratase BJ92ON 3-(4-Chloro-2-hydroxy-phenoxy)chromen-2-one Investigative 72703050 C15H9ClO4 288.68 C1=CC=C2C(=C1)C=C(C(=O)O2)OC3=C(C=C(C=C3)Cl)O IC50 ~ 100000 nM Poor binder T01943 Plasmodium Beta-hydroxyacyl-ACP dehydratase BMQ7J9 7-(4-Chloro-2-Hydroxyphenoxy)-4-Methyl-2h-Chromen-2-One Investigative 71768351 C16H11ClO4 302.71 CC1=CC(=O)OC2=C1C=CC(=C2)OC3=C(C=C(C=C3)Cl)O IC50 ~ 100000 nM Poor binder T01943 Plasmodium Beta-hydroxyacyl-ACP dehydratase BNUJ84 3-(4-Chloro-2-hydroxy-phenoxy)-6-hydroxy-chromen-2-one Investigative 72703242 C15H9ClO5 304.68 C1=CC2=C(C=C1O)C=C(C(=O)O2)OC3=C(C=C(C=C3)Cl)O IC50 ~ 100000 nM Poor binder T01943 Plasmodium Beta-hydroxyacyl-ACP dehydratase BT03UA 3-(4-Chloro-2-hydroxy-phenoxy)-5,7-dihydroxy-chromen-2-one Investigative 72703243 C15H9ClO6 320.68 C1=CC(=C(C=C1Cl)O)OC2=CC3=C(C=C(C=C3OC2=O)O)O IC50 = 90000 nM Poor binder T01943 Plasmodium Beta-hydroxyacyl-ACP dehydratase BTF94C 7-(4-Chloro-2-hydroxyphenoxy)-4-ethylchromen-2-one Investigative 73347724 C17H13ClO4 316.7 CCC1=CC(=O)OC2=C1C=CC(=C2)OC3=C(C=C(C=C3)Cl)O IC50 ~ 100000 nM Poor binder