TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T01575	Sphingosine-1-phosphate lyase 1	D07UHS	Fingolimod	Approved	107970	C19H33NO2	307.5	CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N	IC50 = 52000 nM	Poor binder
T01575	Sphingosine-1-phosphate lyase 1	B0XU8B	N-[2-[(4-Methoxyphenyl)methylamino]-1-phenylethyl]-5-methyl-1,2-oxazole-3-carboxamide	Investigative	127046571	C21H23N3O3	365.4	CC1=CC(=NO1)C(=O)NC(CNCC2=CC=C(C=C2)OC)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T01575	Sphingosine-1-phosphate lyase 1	BW2KS0	N-[2-[(4-Methoxy-2,5-dimethylphenyl)methylamino]-1-(2-methoxyphenyl)ethyl]-5-methyl-1,2-oxazole-3-carboxamide	Investigative	127046410	C24H29N3O4	423.5	CC1=CC(=C(C=C1OC)C)CNCC(C2=CC=CC=C2OC)NC(=O)C3=NOC(=C3)C	IC50 = 50000 nM	Poor binder
T01575	Sphingosine-1-phosphate lyase 1	D0K4YP	THI	Investigative	108037	C9H14N2O5	230.22	CC(=O)C1=NC=C(N1)[C@H]([C@@H]([C@@H](CO)O)O)O	IC50 ~ 100000 nM	Poor binder