TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T01249 HUMAN dCTP pyrophosphatase 1 D06ICW MDI-P Phase 3 4250909 C19H14N2O2 302.3 CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=CC=C3)C4=CC=CC=C4 IC50 ~ 100000 nM Poor binder T01249 HUMAN dCTP pyrophosphatase 1 B2S8ZY 1-[(4-Methoxyphenyl)methyl]benzimidazole Investigative 9152594 C15H14N2O 238.28 COC1=CC=C(C=C1)CN2C=NC3=CC=CC=C32 IC50 ~ 100000 nM Poor binder T01249 HUMAN dCTP pyrophosphatase 1 B8GC3V 6-[4-[(4-Benzylpiperidin-1-yl)methyl]phenyl]-5-methyl-3-phenyl-[1,2]oxazolo[4,5-c]pyridin-4-one Investigative 137637959 C32H31N3O2 489.6 CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=CC=C3)C4=CC=C(C=C4)CN5CCC(CC5)CC6=CC=CC=C6 IC50 ~ 100000 nM Poor binder T01249 HUMAN dCTP pyrophosphatase 1 BC61RP 1-(4-Methoxybenzyl)-2-methyl-1H-benzimidazole Investigative 16995210 C16H16N2O 252.31 CC1=NC2=CC=CC=C2N1CC3=CC=C(C=C3)OC IC50 ~ 100000 nM Poor binder T01249 HUMAN dCTP pyrophosphatase 1 BJ5QD7 5-Methyl-2,3-diphenyl-6-[4-(pyrrolidin-1-ylmethyl)phenyl]furo[3,2-c]pyridin-4-one Investigative 137646447 C31H28N2O2 460.6 CN1C(=CC2=C(C1=O)C(=C(O2)C3=CC=CC=C3)C4=CC=CC=C4)C5=CC=C(C=C5)CN6CCCC6 IC50 ~ 100000 nM Poor binder T01249 HUMAN dCTP pyrophosphatase 1 BMU54N 3,5-Dimethyl-6-phenyl-[1,2]oxazolo[4,5-c]pyridin-4-one Investigative 137643410 C14H12N2O2 240.26 CC1=NOC2=C1C(=O)N(C(=C2)C3=CC=CC=C3)C IC50 ~ 100000 nM Poor binder T01249 HUMAN dCTP pyrophosphatase 1 BW6PN4 1-(4-Methoxybenzyl)-5,6-dimethyl-1H-benzimidazole Investigative 16995008 C17H18N2O 266.34 CC1=CC2=C(C=C1C)N(C=N2)CC3=CC=C(C=C3)OC IC50 ~ 100000 nM Poor binder