TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T01007	HUMAN proteinase activated receptor 2	B0KYB8	5-Isoxazoyl-Cha-Ile-(4-aminophenyl)-(4-[aminomethyl]piperidin-1-yl)methanone	Investigative	49788379	C32H46N6O5	594.7	CC[C@H](C)[C@@H](C(=O)NC1=CC=C(C=C1)C(=O)N2CCC(CC2)CN)NC(=O)[C@H](CC3CCCCC3)NC(=O)C4=CC=NO4	EC50 ~ 50000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	B0V3UO	5-Isoxazoyl-Cha-Ile-4-aminophenyl-(4morpholin-1-yl)ethan-2-one	Investigative	49788505	C31H43N5O6	581.7	CC[C@H](C)[C@@H](C(=O)NC1=CC=C(C=C1)CC(=O)N2CCOCC2)NC(=O)[C@H](CC3CCCCC3)NC(=O)C4=CC=NO4	IC50 = 57000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	B4UK7P	2-Furoyl-Cha-Ile-NH2	Investigative	49788150	C20H31N3O4	377.5	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CC1CCCCC1)NC(=O)C2=CC=CO2	EC50 ~ 50000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	B8YK3H	2-Pyrazoyl-Cha-Ile-NH2	Investigative	49788153	C20H31N5O3	389.5	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CC1CCCCC1)NC(=O)C2=NC=CN=C2	EC50 ~ 100000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	BA26ZU	1,7-Bis(4-methoxyphenyl)heptane-3,5-dione	Investigative	10149969	C21H24O4	340.4	COC1=CC=C(C=C1)CCC(=O)CC(=O)CCC2=CC=C(C=C2)OC	IC50 = 67800 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	BD2FO3	CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN(CC1(C)C)C(=O)OC(C)(C)C)-c1ccc(F)cc1	Investigative	117978042	C27H34FN5O3	495.6	CC(C)C1=CC(=NN2C1=NC(=C2)C(=O)N3CCN(CC3(C)C)C(=O)OC(C)(C)C)C4=CC=C(C=C4)F	IC50 = 51000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	BF1XZ8	4-(2-Methyloxazoyl)-Cha-Ile-NH2	Investigative	49788155	C20H32N4O4	392.5	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CC1CCCCC1)NC(=O)C2=COC(=N2)C	EC50 ~ 100000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	BFIV39	(2S)-2-[[2-[(2-Amino-2-cyclohexylacetyl)amino]acetyl]amino]-5-(diaminomethylideneamino)pentanamide	Investigative	137643158	C16H31N7O3	369.46	C1CCC(CC1)C(C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 ~ 100000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	BXI98U	CC(C)(C)OC(=O)N1CCN(C(=O)c2cn3nc(cc(c3n2)C(C)(C)C)-c2ccc(F)cc2)C(C)(C)C1	Investigative	117977940	C28H36FN5O3	509.6	CC1(CN(CCN1C(=O)C2=CN3C(=N2)C(=CC(=N3)C4=CC=C(C=C4)F)C(C)(C)C)C(=O)OC(C)(C)C)C	IC50 ~ 50000 nM	Poor binder
T01007	HUMAN proteinase activated receptor 2	BY35TZ	(2S)-2-[[2-[[2-[(2-Amino-3-cyclohexylpropanoyl)amino]-2-cyclohexylacetyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanamide	Investigative	137650859	C25H46N8O4	522.7	C1CCC(CC1)CC(C(=O)NC(C2CCCCC2)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 ~ 100000 nM	Poor binder