TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00863	HUMAN lysyl oxidase	B03WMF	3-Tert-Butyl-1-phenyl-2-pyrazolin-5-one	Investigative	245718	C13H16N2O	216.28	CC(C)(C)C1=NN(C(=O)C1)C2=CC=CC=C2	IC50 = 75000 nM	Poor binder
T00863	HUMAN lysyl oxidase	B19FQT	Chembl4238380	Investigative	39047495	C18H15N3O2	305.3	CC1=CC(=C(O1)C)C2=NC3=C(C=C2)C(=O)N(N3)C4=CC=CC=C4	IC50 = 50000 nM	Poor binder
T00863	HUMAN lysyl oxidase	B3TC7F	6-(2-Methoxyphenyl)-2-phenyl-1H-pyrazolo[3,4-b]pyridine-3,4(2H,7H)-dione	Investigative	6459851	C19H15N3O3	333.3	COC1=CC=CC=C1C2=CC(=O)C3=C(N2)NN(C3=O)C4=CC=CC=C4	IC50 = 91000 nM	Poor binder
T00863	HUMAN lysyl oxidase	B5Z4YV	Chembl4237334	Investigative	29130197	C16H11N3OS	293.3	C1=CC=C(C=C1)N2C(=O)C3=C(N2)N=C(C=C3)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T00863	HUMAN lysyl oxidase	B70BWT	4-[4-(Aminomethyl)-5-(4-hydroxybutoxy)pyridin-3-yl]oxybutan-1-ol;dihydrochloride	Investigative	45263146	C14H26Cl2N2O4	357.3	C1=C(C(=C(C=N1)OCCCCO)CN)OCCCCO.Cl.Cl	IC50 = 100000 nM	Poor binder
T00863	HUMAN lysyl oxidase	B7SXF6	2-[4-(Aminomethyl)-5-(2-hydroxyethoxy)pyridin-3-yl]oxyethanol;trihydrate;dihydrochloride	Investigative	45263149	C10H24Cl2N2O7	355.21	C1=C(C(=C(C=N1)OCCO)CN)OCCO.O.O.O.Cl.Cl	IC50 = 100000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BCL9O6	2-Mercapto-3-phenylpyrido[2,3-d]pyrimidin-4(3H)-one	Investigative	13194096	C13H9N3OS	255.3	C1=CC=C(C=C1)N2C(=O)C3=C(NC2=S)N=CC=C3	IC50 ~ 100000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BFZJ36	3-Aminopropanenitrile	Investigative	1647	C3H6N2	70.09	C(CN)C#N	IC50 ~ 100000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BI51VX	(2-(Trifluoromethyl)pyridin-4-yl)methanamine hydrochloride	Investigative	70700688	C7H8ClF3N2	212.6	C1=CN=C(C=C1CN)C(F)(F)F.Cl	IC50 = 54000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BJU18H	(3R)-3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamide	Investigative	122517020	C19H21F3N4O2	394.4	C1C[C@H](CN(C1)C(=O)NC2=CC=CC=C2)OC3=CC(=CC(=N3)C(F)(F)F)CN	IC50 ~ 100000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BK71AW	[3-[4-(Aminomethyl)pyridin-2-yl]oxyphenyl]-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochloride	Investigative	137656044	C17H19ClFN3O3	367.8	C1[C@@H]([C@H](CN1C(=O)C2=CC(=CC=C2)OC3=NC=CC(=C3)CN)F)O.Cl	IC50 = 52000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BN1C3R	[2-(3-Phenoxyphenoxy)-6-(trifluoromethyl)pyridin-4-yl]methanamine	Investigative	122516838	C19H15F3N2O2	360.3	C1=CC=C(C=C1)OC2=CC(=CC=C2)OC3=CC(=CC(=N3)C(F)(F)F)CN	IC50 = 93000 nM	Poor binder
T00863	HUMAN lysyl oxidase	BPO1Q8	3-[4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-methoxybenzamide;hydrochloride	Investigative	122516830	C15H15ClF3N3O3	377.74	CONC(=O)C1=CC(=CC=C1)OC2=CC(=CC(=N2)C(F)(F)F)CN.Cl	IC50 = 83000 nM	Poor binder