TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00602	HUMAN excitatory amino acid transporter 1	B08AIY	(2S,4R)-4-Isobutylglutamic acid	Investigative	11528550	C9H17NO4	203.24	CC(C)C[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 55000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B0BG6A	(2S,4R)-2-Amino-4-(2-cyanoethyl)pentanedioic acid	Investigative	71574837	C8H12N2O4	200.19	C(C[C@H](C[C@@H](C(=O)O)N)C(=O)O)C#N	IC50 = 200000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B0IB8U	(1R,2S)-2-[(S)-Amino(carboxy)methyl]-2-methylcyclobutane-1-carboxylic acid	Investigative	73348758	C8H13NO4	187.19	C[C@@]1(CC[C@H]1C(=O)O)[C@@H](C(=O)O)N	Ki = 200000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B3ADQ6	L-Serine O-sulfate	Investigative	164701	C3H7NO6S	185.16	C([C@@H](C(=O)O)N)OS(=O)(=O)O	IC50 = 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B3DN1I	(2S)-2-Amino-3-[(2,6-dichlorophenyl)sulfonylamino]butanedioic acid	Investigative	134148109	C10H10Cl2N2O6S	357.2	C1=CC(=C(C(=C1)Cl)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B4X0MG	(2S,3R)-2-Amino-3-(benzenesulfonamido)butanedioic acid	Investigative	134132565	C10H12N2O6S	288.28	C1=CC=C(C=C1)S(=O)(=O)N[C@H]([C@@H](C(=O)O)N)C(=O)O	IC50 = 199526.23 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B68CPT	(2S)-2-Amino-3-(phenoxycarbonylamino)butanedioic acid	Investigative	134134123	C11H12N2O6	268.22	C1=CC=C(C=C1)OC(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 70000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B7HY2T	(2S,4R)-2-Amino-4-[2-(phenylmethoxycarbonylamino)ethyl]pentanedioic acid	Investigative	71574836	C15H20N2O6	324.33	C1=CC=C(C=C1)COC(=O)NCC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 = 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B82ERW	(RS)-2-amino-3-(1-hydroxy-1,2,3-triazol-5-yl)propionate	Investigative	10464763	C5H8N4O3	172.14	C1=C(N(N=N1)O)CC(C(=O)O)N	IC50 = 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B85MTV	(2S)-2-Amino-3-(naphthalen-1-ylsulfonylamino)butanedioic acid	Investigative	134149841	C14H14N2O6S	338.34	C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 64565.42 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	B8H0SP	(1s,2r)-2-[(S)-Amino(Carboxy)methyl]cyclobutanecarboxylic Acid	Investigative	44417425	C7H11NO4	173.17	C1C[C@@H]([C@@H]1[C@@H](C(=O)O)N)C(=O)O	Ki = 200000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BA0T9H	(2S,4R)-4-Butylglutamic acid	Investigative	11651356	C9H17NO4	203.24	CCCC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 50000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BA5F1H	(1R,4S,5R,6S)-3-Azabicyclo[3.3.0]octane-4,6-dicarboxylic acid	Investigative	11543205	C9H13NO4	199.2	C1C[C@@H]([C@H]2[C@@H]1CN[C@@H]2C(=O)O)C(=O)O	Ki = 127000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BDIM12	Chembl4168620	Investigative	145953224	C6H8N2O5	188.14	C(C#N)O[C@@H]([C@H](C(=O)O)N)C(=O)O	IC50 = 99000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BF7AK0	Chembl4161764	Investigative	145958688	C8H13NO5	203.19	C1CC1CO[C@@H]([C@H](C(=O)O)N)C(=O)O	IC50 = 87000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BG65XA	5-Oxo-4,7-Diphenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile	Investigative	49783035	C22H17NO2	327.4	C1C(CC(=O)C2=C1OC=C(C2C3=CC=CC=C3)C#N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BL38EA	(2S)-2-Amino-3-[[3-(trifluoromethyl)phenyl]sulfonylamino]butanedioic acid	Investigative	134136786	C11H11F3N2O6S	356.28	C1=CC(=CC(=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)C(F)(F)F	IC50 = 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BO37UI	N-(3-Cyano-5-oxo-4,7-diphenyl-4,6,7,8-tetrahydrochromen-2-yl)acetamide	Investigative	49782835	C24H20N2O3	384.4	CC(=O)NC1=C(C(C2=C(O1)CC(CC2=O)C3=CC=CC=C3)C4=CC=CC=C4)C#N	IC50 ~ 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BSRH61	(2S,4R)-4-Pentylglutamic acid	Investigative	10680281	C10H19NO4	217.26	CCCCC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 117489.76 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BT4Z1N	(2S)-2-Amino-3-[(3,5-dimethylphenyl)sulfonylamino]butanedioic acid	Investigative	134140490	C12H16N2O6S	316.33	CC1=CC(=CC(=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)C	IC50 = 63000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BUD1X2	(2S)-2-Amino-4-[4-methyl-3-[3-(trifluoromethyl)phenyl]anilino]-4-oxobutanoic acid	Investigative	71452729	C18H17F3N2O3	366.3	CC1=C(C=C(C=C1)NC(=O)C[C@@H](C(=O)O)N)C2=CC(=CC=C2)C(F)(F)F	IC50 = 63000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BUJL57	(3S)-3-Methoxyaspartic acid	Investigative	12047098	C5H9NO5	163.13	CO[C@@H]([C@@H](C(=O)O)N)C(=O)O	IC50 = 69000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	BVR2I0	(2S)-2-Amino-4-(4-naphthalen-2-ylanilino)-4-oxobutanoic acid	Investigative	71450917	C20H18N2O3	334.4	C1=CC=C2C=C(C=CC2=C1)C3=CC=C(C=C3)NC(=O)C[C@@H](C(=O)O)N	IC50 = 100000 nM	Poor binder
T00602	HUMAN excitatory amino acid transporter 1	D09HET	L-beta-BA	Investigative	11622683	C11H13NO4	223.22	C1=CC=C(C=C1)C[C@@H]([C@@H](C(=O)O)N)C(=O)O	IC50 = 51000 nM	Poor binder