TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T99685 HUMAN mammalian target of rapamycin D0H9IX PMID28870136-Compound-52 Patented 2519 C8H10N4O2 194.19 CN1C=NC2=C1C(=O)N(C(=O)N2C)C IC50 = 400000 nM Non binder T99685 HUMAN mammalian target of rapamycin B5S4XD 5-[2-[(4-Methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]-4-(trifluoromethyl)pyrimidin-2-amine Investigative 70693248 C21H26F3N9O3S 541.6 CS(=O)(=O)N1CCN(CC1)CC2=CN3C=C(N=C(C3=N2)N4CCOCC4)C5=CN=C(N=C5C(F)(F)F)N IC50 = 10000000 nM Non binder T99685 HUMAN mammalian target of rapamycin BBD29U 4-[4-[6-Bromo-4-(trifluoromethyl)pyridin-3-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine Investigative 137637823 C17H18BrF3N6O2 475.3 C1COCCN1C2=NC(=NC(=N2)C3=CN=C(C=C3C(F)(F)F)Br)N4CCOCC4 Ki = 660000 nM Non binder