TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T99665 GABA(A) receptor rho1 B0IL7M 4-Amino-N-propylcyclopentene-1-carboxamide Investigative 71746980 C9H16N2O 168.24 CCCNC(=O)C1=CCC(C1)N IC50 = 570000 nM Non binder T99665 GABA(A) receptor rho1 B5W0AP 6-Amino-2-ethylpyridine-3-carboxylic acid Investigative 22019116 C8H10N2O2 166.18 CCC1=C(C=CC(=N1)N)C(=O)O EC50 > 1000000 nM Non binder T99665 GABA(A) receptor rho1 B7KJN4 (5-Chloro-1-hydroxypyrazol-4-yl)methanamine Investigative 71561429 C4H6ClN3O 147.56 C1=NN(C(=C1CN)Cl)O EC50 > 500000 nM Non binder T99665 GABA(A) receptor rho1 B8JZR7 cis-2-Aminocyclopropanecarboxylic acid Investigative 28881824 C4H7NO2 101.1 C1[C@H]([C@H]1N)C(=O)O IC50 = 890000 nM Non binder T99665 GABA(A) receptor rho1 B9D4EC 4-Amino-N-methylcyclopentene-1-carboxamide Investigative 71746979 C7H12N2O 140.18 CNC(=O)C1=CCC(C1)N IC50 = 408300 nM Non binder T99665 GABA(A) receptor rho1 BB6K1R (1-Hydroxy-5-methylpyrazol-4-yl)methanamine Investigative 71717372 C5H9N3O 127.14 CC1=C(C=NN1O)CN EC50 > 500000 nM Non binder T99665 GABA(A) receptor rho1 BBF8W2 6-Amino-4-butylpyridine-3-carboxylic acid Investigative 118710366 C10H14N2O2 194.23 CCCCC1=CC(=NC=C1C(=O)O)N EC50 > 1000000 nM Non binder T99665 GABA(A) receptor rho1 BC7D8M 6-Amino-2-butylpyridine-3-carboxylic acid Investigative 118710364 C10H14N2O2 194.23 CCCCC1=C(C=CC(=N1)N)C(=O)O EC50 > 1000000 nM Non binder T99665 GABA(A) receptor rho1 BFY7L0 (1-Hydroxy-3-phenylpyrazol-4-yl)methanamine Investigative 71561443 C10H11N3O 189.21 C1=CC=C(C=C1)C2=NN(C=C2CN)O EC50 > 500000 nM Non binder T99665 GABA(A) receptor rho1 BG1H0Q (3-Ethyl-1-hydroxypyrazol-4-yl)methanamine Investigative 71561439 C6H11N3O 141.17 CCC1=NN(C=C1CN)O EC50 > 500000 nM Non binder T99665 GABA(A) receptor rho1 BPA8N2 (1-Hydroxy-3-iodopyrazol-4-yl)methanamine Investigative 71561435 C4H6IN3O 239.01 C1=C(C(=NN1O)I)CN EC50 > 500000 nM Non binder T99665 GABA(A) receptor rho1 BPH5K7 [1-Hydroxy-3-(3-phenylphenyl)pyrazol-4-yl]methanamine Investigative 71719189 C16H15N3O 265.31 C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NN(C=C3CN)O EC50 > 500000 nM Non binder T99665 GABA(A) receptor rho1 BRCG43 6-Amino-4-ethylpyridine-3-carboxylic acid Investigative 68419998 C8H10N2O2 166.18 CCC1=CC(=NC=C1C(=O)O)N EC50 > 1000000 nM Non binder T99665 GABA(A) receptor rho1 BZ5X7A [1-Hydroxy-3-(4-phenylphenyl)pyrazol-4-yl]methanamine Investigative 71561568 C16H15N3O 265.31 C1=CC=C(C=C1)C2=CC=C(C=C2)C3=NN(C=C3CN)O EC50 > 500000 nM Non binder