TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97822	Prostaglandin synthetase	D0U2FN	Romazarit	Preclinical	71321	C15H16ClNO4	309.74	CC1=C(OC(=N1)C2=CC=C(C=C2)Cl)COC(C)(C)C(=O)O	IC50 = 6500000 nM	Non binder
T97822	Prostaglandin synthetase	B1DF3I	Clobuzarit	Investigative	71697	C17H17ClO3	304.8	CC(C)(C(=O)O)OCC1=CC=C(C=C1)C2=CC=C(C=C2)Cl	IC50 = 950000 nM	Non binder
T97822	Prostaglandin synthetase	B3N8XJ	2-(3-Chloro-2-methylphenylamino)benzeneacetic acid	Investigative	14762943	C15H14ClNO2	275.73	CC1=C(C=CC=C1Cl)NC2=CC=CC=C2CC(=O)O	IC50 = 91201083.94 nM	Non binder
T97822	Prostaglandin synthetase	B4OS9N	2-[2-(2,5-Dioxopyrrol-1-yl)ethoxy]benzoic acid	Investigative	10801359	C13H11NO5	261.23	C1=CC=C(C(=C1)C(=O)O)OCCN2C(=O)C=CC2=O	IC50 = 250000 nM	Non binder
T97822	Prostaglandin synthetase	B7Y4BQ	3'-Hydroxydiclofenac	Investigative	112230	C14H11Cl2NO3	312.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC(=C2Cl)O)Cl	IC50 = 100000000 nM	Non binder
T97822	Prostaglandin synthetase	B8ZI9D	2-[(3,4-Dichlorophenyl)amino]phenylacetic acid	Investigative	14762954	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=CC(=C(C=C2)Cl)Cl	IC50 = 7079457.84 nM	Non binder
T97822	Prostaglandin synthetase	B92JKD	2-(2-Chloro-6-iodophenylamino)benzeneacetic acid	Investigative	14762939	C14H11ClINO2	387.6	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2I)Cl	IC50 = 501187233.6 nM	Non binder
T97822	Prostaglandin synthetase	B9C0VQ	2-(2,6-Dichloro-3-methylphenylamino)benzeneacetic acid sodium salt	Investigative	23680227	C15H12Cl2NNaO2	332.2	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2CC(=O)[O-])Cl.[Na+]	IC50 = 70794578.44 nM	Non binder
T97822	Prostaglandin synthetase	BB37RC	2-(2,6-Difluorophenylamino)benzeneacetic acid sodium salt	Investigative	23680216	C14H10F2NNaO2	285.22	C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2F)F.[Na+]	IC50 = 4365158.32 nM	Non binder
T97822	Prostaglandin synthetase	BC8PM7	5-Hydroxydiclofenac	Investigative	3052566	C14H11Cl2NO3	312.1	C1=CC(=C(C(=C1)Cl)NC2=C(C=C(C=C2)O)CC(=O)O)Cl	IC50 = 446683.59 nM	Non binder
T97822	Prostaglandin synthetase	BD63PN	5-Chloro-2-(2,6-dichlorophenylamino)benzeneacetic acid sodium salt	Investigative	44315480	C14H9Cl3NNaO2	352.6	C1=CC(=C(C(=C1)Cl)NC2=C(C=C(C=C2)Cl)CC(=O)[O-])Cl.[Na+]	IC50 = 794328234.7 nM	Non binder
T97822	Prostaglandin synthetase	BD8M3Q	6-Maleimidocaproic acid	Investigative	573683	C10H13NO4	211.21	C1=CC(=O)N(C1=O)CCCCCC(=O)O	IC50 > 800000 nM	Non binder
T97822	Prostaglandin synthetase	BD93NV	[2-(2,3-Dimethylanilino)phenyl]acetic acid	Investigative	14762938	C16H17NO2	255.31	CC1=C(C(=CC=C1)NC2=CC=CC=C2CC(=O)O)C	IC50 = 501187233.6 nM	Non binder
T97822	Prostaglandin synthetase	BE5JO0	5-Fluoro-2-(2,6-dichlorophenylamino)benzeneacetic acid sodium salt	Investigative	23680229	C14H9Cl2FNNaO2	336.1	C1=CC(=C(C(=C1)Cl)NC2=C(C=C(C=C2)F)CC(=O)[O-])Cl.[Na+]	IC50 = 741310241.3 nM	Non binder
T97822	Prostaglandin synthetase	BF5AC0	6-Bromo-2-(2,6-dichlorophenylamino)benzeneacetic acid	Investigative	23275601	C14H10BrCl2NO2	375	C1=CC(=C(C(=C1)Br)CC(=O)O)NC2=C(C=CC=C2Cl)Cl	IC50 = 66069344.8 nM	Non binder
T97822	Prostaglandin synthetase	BFWT37	2-[(2,6-Dichloro-3-methoxy-4-hydroxyphenyl)amino]phenylacetic acid	Investigative	14762923	C15H13Cl2NO4	342.2	COC1=C(C(=C(C=C1O)Cl)NC2=CC=CC=C2CC(=O)O)Cl	IC50 = 13803842.65 nM	Non binder
T97822	Prostaglandin synthetase	BI96HF	7-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)heptanoic acid	Investigative	10513373	C11H15NO4	225.24	C1=CC(=O)N(C1=O)CCCCCCC(=O)O	IC50 = 570000 nM	Non binder
T97822	Prostaglandin synthetase	BK2W6L	2-Anilinophenylacetic acid	Investigative	854057	C14H13NO2	227.26	C1=CC=C(C=C1)NC2=CC=CC=C2CC(=O)O	IC50 = 3467368.5 nM	Non binder
T97822	Prostaglandin synthetase	BKJB67	2-[(2,3-Dichlorophenyl)amino]phenylacetic acid	Investigative	14762942	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C(=CC=C2)Cl)Cl	IC50 = 100000000 nM	Non binder
T97822	Prostaglandin synthetase	BM6X7H	5-Chloro-2-(2,3,5,6-tetramethylphenylamino)benzeneacetic acid	Investigative	44315519	C18H20ClNO2	317.8	CC1=CC(=C(C(=C1C)NC2=C(C=C(C=C2)Cl)CC(=O)O)C)C	IC50 = 15135612.48 nM	Non binder
T97822	Prostaglandin synthetase	BMD76T	2-(2,4-Difluorophenylamino)benzeneacetic acid sodium salt	Investigative	23680215	C14H10F2NNaO2	285.22	C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=C(C=C2)F)F.[Na+]	IC50 = 9772372.21 nM	Non binder
T97822	Prostaglandin synthetase	BO1YS4	Benzeneacetic acid, 2-[(3,5-dichlorophenyl)amino]-	Investigative	10469807	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=CC(=CC(=C2)Cl)Cl	IC50 = 12589254.12 nM	Non binder
T97822	Prostaglandin synthetase	BOUM07	2-(2-Chloro-6-fluorophenylamino)benzeneacetic acid sodium salt	Investigative	23680221	C14H10ClFNNaO2	301.67	C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)F.[Na+]	IC50 = 17782794.1 nM	Non binder
T97822	Prostaglandin synthetase	BT7C4Z	4'-Hydroxydiclofenac	Investigative	116545	C14H11Cl2NO3	312.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=C(C=C2Cl)O)Cl	IC50 = 7079457.84 nM	Non binder
T97822	Prostaglandin synthetase	BTKY67	2-[(2,4-Dichlorophenyl)amino]phenylacetic acid	Investigative	13556944	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=C(C=C2)Cl)Cl	IC50 = 14125375.45 nM	Non binder
T97822	Prostaglandin synthetase	BUBA52	5-Fluoro-2-(2,6-dichloro-4-fluorophenylamino)benzeneacetic acid sodium salt	Investigative	23689693	C14H8Cl2F2NNaO2	354.1	C1=CC(=C(C=C1F)CC(=O)[O-])NC2=C(C=C(C=C2Cl)F)Cl.[Na+]	IC50 = 562341325.2 nM	Non binder
T97822	Prostaglandin synthetase	BW2FP6	4',5-Dihydroxydiclofenac	Investigative	3052567	C14H11Cl2NO4	328.1	C1=CC(=C(C=C1O)CC(=O)O)NC2=C(C=C(C=C2Cl)O)Cl	IC50 = 912010.84 nM	Non binder
T97822	Prostaglandin synthetase	BW7C0I	2-[(2-Chloro-3-methylphenyl)amino]phenylacetic acid	Investigative	14762948	C15H14ClNO2	275.73	CC1=C(C(=CC=C1)NC2=CC=CC=C2CC(=O)O)Cl	IC50 = 50118723.36 nM	Non binder
T97822	Prostaglandin synthetase	BW8G5J	2-(2,6-Dichloro-4-fluorophenylamino)benzeneacetic acid sodium salt	Investigative	23680230	C14H9Cl2FNNaO2	336.1	C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=C(C=C2Cl)F)Cl.[Na+]	IC50 = 891250938.1 nM	Non binder
T97822	Prostaglandin synthetase	BW94BP	Sodium;2-[2-(2,6-dichloroanilino)-6-hydroxyphenyl]acetate	Investigative	23680228	C14H10Cl2NNaO3	334.1	C1=CC(=C(C(=C1)O)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+]	IC50 = 4677351.41 nM	Non binder
T97822	Prostaglandin synthetase	BWDX49	Sodium [2-(2-bromo-6-chloroanilino)phenyl]acetate	Investigative	23680224	C14H10BrClNNaO2	362.58	C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Br)Cl.[Na+]	IC50 = 524807460.3 nM	Non binder
T97822	Prostaglandin synthetase	BY2T3G	2-Carboxy-5-Maleimidophenyl Acetate	Investigative	10492615	C13H9NO6	275.21	CC(=O)OC1=C(C=CC(=C1)N2C(=O)C=CC2=O)C(=O)O	IC50 > 300000 nM	Non binder
T97822	Prostaglandin synthetase	BY69GT	2-(2,3,5,6-Tetramethylphenylamino)benzeneacetic acid	Investigative	14762940	C18H21NO2	283.4	CC1=CC(=C(C(=C1C)NC2=CC=CC=C2CC(=O)O)C)C	IC50 = 165958690.7 nM	Non binder
T97822	Prostaglandin synthetase	BY75UF	2-[(2,6-Diethylphenyl)amino]phenylacetic acid	Investigative	14762951	C18H21NO2	283.4	CCC1=C(C(=CC=C1)CC)NC2=CC=CC=C2CC(=O)O	IC50 = 14791083.88 nM	Non binder
T97822	Prostaglandin synthetase	BZGM76	3'-Hydroxy-4'-methoxydiclofenac	Investigative	129615	C15H13Cl2NO4	342.2	COC1=CC(=C(C(=C1O)Cl)NC2=CC=CC=C2CC(=O)O)Cl	IC50 = 3388441.56 nM	Non binder
T97822	Prostaglandin synthetase	BZI51L	[2-(2,6-Dichloro-3-methoxyanilino)phenyl]acetic acid	Investigative	14762944	C15H13Cl2NO3	326.2	COC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2CC(=O)O)Cl	IC50 = 91201083.94 nM	Non binder
T97822	Prostaglandin synthetase	D05EMX	2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid	Investigative	14076674	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC(=C2)Cl)Cl	IC50 = 10000000 nM	Non binder
T97822	Prostaglandin synthetase	D08GOT	2-(2-(2-chlorophenylamino)phenyl)acetic acid	Investigative	13752584	C14H12ClNO2	261.7	C1=CC=C(C(=C1)CC(=O)O)NC2=CC=CC=C2Cl	IC50 = 4897788.19 nM	Non binder
T97822	Prostaglandin synthetase	D0U0YE	2-(2-(2,6-dimethylphenylamino)phenyl)acetic acid	Investigative	14762941	C16H17NO2	255.31	CC1=C(C(=CC=C1)C)NC2=CC=CC=C2CC(=O)O	IC50 = 165958690.7 nM	Non binder