TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T95302	Melanocortin receptor 5	B4GUO7	N-(4-(Diethylamino)benzyl)-4-(1H-indol-3-yl)-N-pentylbutanamide	Investigative	44434561	C28H39N3O	433.6	CCCCCN(CC1=CC=C(C=C1)N(CC)CC)C(=O)CCCC2=CNC3=CC=CC=C32	Ki = 408000 nM	Non binder
T95302	Melanocortin receptor 5	B4KSN6	N-(4-Aminobutyl)-N-isopropyl-1H-indole-3-carboxamide	Investigative	44434625	C16H23N3O	273.37	CC(C)N(CCCCN)C(=O)C1=CNC2=CC=CC=C21	Ki = 279000 nM	Non binder
T95302	Melanocortin receptor 5	B6UD5G	3-(Piperazin-1-ylmethyl)-1H-indole	Investigative	17880880	C13H17N3	215.29	C1CN(CCN1)CC2=CNC3=CC=CC=C32	Ki = 256000 nM	Non binder
T95302	Melanocortin receptor 5	B85LMZ	N-(2-Bromo-4,5-dimethoxycinnamyl)-N-(4-((4-aminocyclohexyl)methyl)cyclohexyl)-4-(1H-indol-3-yl)butanamide	Investigative	44434757	C36H48BrN3O3	650.7	COC1=C(C=C(C(=C1)/C=C/CN(C2CCC(CC2)CC3CCC(CC3)N)C(=O)CCCC4=CNC5=CC=CC=C54)Br)OC	Ki = 266000 nM	Non binder
T95302	Melanocortin receptor 5	B91VPO	N-(3-Bromo-4-methoxybenzyl)-N-(4-((4-aminocyclohexyl)methyl)cyclohexyl)-4-(1H-indol-3-yl)butanamide	Investigative	44434715	C33H44BrN3O2	594.6	COC1=C(C=C(C=C1)CN(C2CCC(CC2)CC3CCC(CC3)N)C(=O)CCCC4=CNC5=CC=CC=C54)Br	Ki = 278000 nM	Non binder
T95302	Melanocortin receptor 5	B9Q7KP	N-(3-Aminopropyl)-5-(benzyloxy)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)-1H-indole-2-carboxamide	Investigative	44434613	C29H31N3O2	453.6	C1CC2=CC=CC=C2CC1N(CCCN)C(=O)C3=CC4=C(N3)C=CC(=C4)OCC5=CC=CC=C5	Ki = 681000 nM	Non binder
T95302	Melanocortin receptor 5	BA9C5Y	(1R,4S,6R)-N-[(2R)-1-[4-(Tert-butylcarbamoyl)-4-cyclohexylpiperidin-1-yl]-3-(4-fluorophenyl)-1-oxopropan-2-yl]-7-methyl-7-azabicyclo[2.2.2]octane-6-carboxamide	Investigative	6918851	C34H51FN4O3	582.8	CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](CC2=CC=C(C=C2)F)NC(=O)[C@@H]3C[C@@H]4CC[C@H]3N(C4)C)C5CCCCC5	EC50 = 850000 nM	Non binder
T95302	Melanocortin receptor 5	BFR29T	N-(3-Guanidinopropyl)-1-(2-naphthylmethyl)-4alpha-hydroxy-L-prolinamide	Investigative	44265681	C20H27N5O2	369.5	C1[C@@H](CN([C@@H]1C(=O)NCCCN=C(N)N)CC2=CC3=CC=CC=C3C=C2)O	Ki = 221000 nM	Non binder
T95302	Melanocortin receptor 5	BG6U3I	(2S)-5-(Diaminomethylideneamino)-N-[3-(diaminomethylideneamino)propyl]-2-(naphthalen-2-ylmethylamino)pentanamide	Investigative	44265751	C21H32N8O	412.5	C1=CC=C2C=C(C=CC2=C1)CN[C@@H](CCCN=C(N)N)C(=O)NCCCN=C(N)N	Ki = 1000000 nM	Non binder
T95302	Melanocortin receptor 5	BJ3GQ5	N-((1R,2R)-2-Aminocyclohexyl)-N-cinnamyl-4-(1H-indol-3-yl)butanamide	Investigative	44434853	C27H33N3O	415.6	C1CC[C@H]([C@@H](C1)N)N(C/C=C/C2=CC=CC=C2)C(=O)CCCC3=CNC4=CC=CC=C43	Ki = 555000 nM	Non binder
T95302	Melanocortin receptor 5	BKT82V	4-(1H-Indole-3-ylmethyl)-1-piperazinecarboxamidine	Investigative	44265225	C14H19N5	257.329	C1CN(CCN1CC2=CNC3=CC=CC=C32)C(=N)N	Ki > 1000000 nM	Non binder
T95302	Melanocortin receptor 5	BT1SG3	N-(3-Aminopropyl)-2-naphthalen-2-yl-N-(naphthalen-2-ylmethyl)acetamide	Investigative	10293285	C26H26N2O	382.5	C1=CC=C2C=C(C=CC2=C1)CC(=O)N(CCCN)CC3=CC4=CC=CC=C4C=C3	Ki = 267000 nM	Non binder
T95302	Melanocortin receptor 5	BV6I0Q	2-(4-Hydroxybenzyl)-N-(4-aminobutyl)-N-isopropyl-1H-indole-3-carboxamide	Investigative	44434631	C23H29N3O2	379.5	CC(C)N(CCCCN)C(=O)C1=C(NC2=CC=CC=C21)CC3=CC=C(C=C3)O	Ki = 353000 nM	Non binder