TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T93145 Pyruvate dehydrogenase kinase BD20HS 3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(3-nitrophenyl)propanamide Investigative 44312358 C10H9F3N2O4 278.18 CC(C(=O)NC1=CC(=CC=C1)[N+](=O)[O-])(C(F)(F)F)O IC50 = 220000 nM Non binder T93145 Pyruvate dehydrogenase kinase BKA71N N-(2-Benzoylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Investigative 21480124 C17H14F3NO3 337.29 CC(C(=O)NC1=CC=CC=C1C(=O)C2=CC=CC=C2)(C(F)(F)F)O IC50 = 203000 nM Non binder T93145 Pyruvate dehydrogenase kinase BZ7W8L Dichloroacetic acid Investigative 6597 C2H2Cl2O2 128.94 C(C(=O)O)(Cl)Cl IC50 > 2000000 nM Non binder