TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T92653 Neuropeptide Y receptor type 2 B0JAI2 2-Diphenylacetylamino-5-guanidino-pentanoic acid [1-(4-hydroxy-phenyl)-ethyl]-amide Investigative 44288112 C28H33N5O3 487.6 CC(C1=CC=C(C=C1)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3 IC50 = 575000 nM Non binder T92653 Neuropeptide Y receptor type 2 B35VLW 2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-2-hydroxy-1-phenyl-ethyl)-amide Investigative 44287971 C28H33N5O3 487.6 C1=CC=C(C=C1)[C@@H](CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3 IC50 = 540000 nM Non binder T92653 Neuropeptide Y receptor type 1 B40DXV N-(6-(2-(5-Ethyl-4-methyloxazol-2-yl)ethyl)-4-morpholinopyridin-2-yl)acetamide Investigative 45269119 C19H26N4O3 358.4 CCC1=C(N=C(O1)CCC2=NC(=CC(=C2)N3CCOCC3)NC(=O)C)C IC50 = 320000 nM Non binder T92653 Neuropeptide Y receptor type 2 B57TIV N-[4-Guanidino-1-(7-hydroxy-1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-butyl]-2,2-diphenyl-acetamide Investigative 44288067 C30H35N5O3 513.6 C1CC2=C(CN(C1)C(=O)C(CCCN=C(N)N)NC(=O)C(C3=CC=CC=C3)C4=CC=CC=C4)C=CC(=C2)O IC50 = 247000 nM Non binder T92653 Neuropeptide Y receptor type 2 B9BLS5 2-Diphenylacetylamino-5-guanidino-pentanoic acid ((R)-carbamoyl-phenyl-methyl)-amide Investigative 44287982 C28H32N6O3 500.6 C1=CC=C(C=C1)[C@H](C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3 IC50 > 400000 nM Non binder T92653 Neuropeptide Y receptor type 1 BSRK79 2-(6-((4,5-Dimethyloxazol-2-yloxy)methyl)-4-morpholinopyridin-2-ylamino)acetonitrile Investigative 45267391 C17H21N5O3 343.4 CC1=C(OC(=N1)OCC2=NC(=CC(=C2)N3CCOCC3)NCC#N)C IC50 > 1000000 nM Non binder