TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T83813	5-HT 2C receptor	B0V4ZE	3-[(Dipropylamino)methyl]-5-methoxy-N,N-dipropyl-2,4-dihydrochromen-3-amine	Investigative	44267215	C23H40N2O2	376.6	CCCN(CCC)CC1(CC2=C(C=CC=C2OC)OC1)N(CCC)CCC	IC50 = 2140000000000 nM	Non binder
T83813	5-HT 2C receptor	B1A0KF	4h-Isoxazolo[4,5-d]azepine,5,6,7,8-tetrahydro-3-methoxy-	Investigative	14515726	C8H12N2O2	168.19	COC1=NOC2=C1CCNCC2	Ki = 300000 nM	Non binder
T83813	5-HT 2C receptor	B1OP6Y	2-[Methyl-(2-morpholin-4-yl-2-oxoethyl)amino]-1-(2-phenyl-1H-indol-3-yl)ethanone	Investigative	9044803	C23H25N3O3	391.5	CN(CC(=O)C1=C(NC2=CC=CC=C21)C3=CC=CC=C3)CC(=O)N4CCOCC4	IC50 = 213796.21 nM	Non binder
T83813	5-HT 2C receptor	B1VRZ9	8-[4-(3,4-Dihydro-2H-chromen-3-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione	Investigative	10091430	C23H32N2O3	384.5	C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCNCC3CC4=CC=CC=C4OC3	IC50 = 813000000000000 nM	Non binder
T83813	5-HT 2C receptor	B31EOD	Schembl21373245	Investigative	122195454	C23H27N3O2	377.5	CN(CCN1CCOCC1)CC(=O)C2=C(NC3=CC=CC=C32)C4=CC=CC=C4	IC50 = 269000 nM	Non binder
T83813	5-HT 2C receptor	B3B8UO	8-(4-Benzylpiperazin-1-yl)-4-phenyl-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10502452	C26H24N4S	424.6	C1CN(CCN1CC2=CC=CC=C2)C3=NC4=C(N5C3=CC=C5)SC(=C4)C6=CC=CC=C6	IC50 = 467735.14 nM	Non binder
T83813	5-HT 2C receptor	B4MCT9	2-Benzyl-4,5,6,7-tetrahydro-[1,2]oxazolo[4,5-c]pyridin-3-one	Investigative	71562666	C13H14N2O2	230.26	C1CNCC2=C1ON(C2=O)CC3=CC=CC=C3	EC50 > 1000000 nM	Non binder
T83813	5-HT 2C receptor	B4RNL0	4'-Benzyl-5-methoxy-1'-propylspiro[2,4-dihydrochromene-3,2'-piperazine]	Investigative	44267205	C23H30N2O2	366.5	CCCN1CCN(CC12CC3=C(C=CC=C3OC)OC2)CC4=CC=CC=C4	IC50 = 12900000000000 nM	Non binder
T83813	5-HT 2C receptor	B5T1NG	8-[4-[5'-Methoxyspiro[pyrrolidine-2,3'(4'H)-[2H-1]benzopyran]-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione	Investigative	9911120	C26H36N2O4	440.6	COC1=CC=CC2=C1CC3(CCCN3CCCCN4C(=O)CC5(CCCC5)CC4=O)CO2	IC50 = 95500000000000 nM	Non binder
T83813	5-HT 2C receptor	B60KLD	2-Ethyl-4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one	Investigative	71562549	C8H12N2O2	168.19	CCN1C(=O)C2=C(O1)CNCC2	EC50 > 1000000 nM	Non binder
T83813	5-HT 2C receptor	B6U5NF	3-Methoxy-6-methyl-4,5,7,8-tetrahydro-[1,2]oxazolo[4,5-d]azepine	Investigative	71562662	C9H14N2O2	182.22	CN1CCC2=C(CC1)ON=C2OC	Ki > 300000 nM	Non binder
T83813	5-HT 2C receptor	B7U0WO	Schembl21373240	Investigative	122195453	C26H29N3O3	431.5	C1CC(CN(C1)CC(=O)C2=C(NC3=CC=CC=C32)C4=CC=CC=C4)C(=O)N5CCOCC5	IC50 = 208929.61 nM	Non binder
T83813	5-HT 2C receptor	B8TGK3	4-Phenyl-8-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10790813	C26H21F3N4S	478.5	C1CN(CCN1C2=CC=CC(=C2)C(F)(F)F)C3=NC4=C(N5C3=CC=C5)SC(=C4)C6=CC=CC=C6	IC50 = 213796.21 nM	Non binder
T83813	5-HT 2C receptor	B8XI7A	8-(4-Benzylpiperazin-1-yl)-4-phenyl-5-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaene	Investigative	10526362	C26H24N4S	424.6	C1CN(CCN1CC2=CC=CC=C2)C3=NC4=C(C=C(S4)C5=CC=CC=C5)N6C3=CC=C6	IC50 = 1000000 nM	Non binder
T83813	5-HT 2C receptor	B8YJ7S	2-Benzyl-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-c]azepin-3-one	Investigative	71562667	C14H16N2O2	244.29	C1CC2=C(CNC1)C(=O)N(O2)CC3=CC=CC=C3	EC50 > 1000000 nM	Non binder
T83813	5-HT 2C receptor	B94WDN	1-[2-Hydroxy-3-methyl-4-[[4-[4-(2H-tetrazol-5-yl)pyridin-2-yl]oxyphenyl]methoxy]phenyl]ethanone	Investigative	11596869	C22H19N5O4	417.4	CC1=C(C=CC(=C1O)C(=O)C)OCC2=CC=C(C=C2)OC3=NC=CC(=C3)C4=NNN=N4	Ki > 7870000 nM	Non binder
T83813	5-HT 2C receptor	BA8EQ3	2-Ethyl-6-methyl-4,5,7,8-tetrahydro-[1,2]oxazolo[4,5-d]azepin-3-one	Investigative	14515728	C10H16N2O2	196.25	CCN1C(=O)C2=C(O1)CCN(CC2)C	Ki > 300000 nM	Non binder
T83813	5-HT 2C receptor	BC6OV8	CID 14515722	Investigative	14515722	C8H12N2O2	168.19	CN1C(=O)C2=C(O1)CCNCC2	Ki > 300000 nM	Non binder
T83813	5-HT 2C receptor	BD1G2K	2-Ethyl-4,5,6,7-tetrahydro-[1,2]oxazolo[4,5-c]pyridin-3-one	Investigative	71562665	C8H12N2O2	168.19	CCN1C(=O)C2=C(O1)CCNC2	EC50 > 1000000 nM	Non binder
T83813	5-HT 2C receptor	BI3BQ1	8-[4-[(5-Methoxy-3,4-dihydro-2H-chromen-3-yl)methyl-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione	Investigative	44267161	C27H40N2O4	456.6	CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)CC3CC4=C(C=CC=C4OC)OC3	IC50 = 316000000000000 nM	Non binder
T83813	5-HT 2C receptor	BN8HE2	3-Ethoxy-6-methyl-4,5,7,8-tetrahydro-[1,2]oxazolo[4,5-d]azepine	Investigative	71562663	C10H16N2O2	196.25	CCOC1=NOC2=C1CCN(CC2)C	Ki > 300000 nM	Non binder
T83813	5-HT 2C receptor	BQ2ST7	8-[4-[(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10718731	C26H23ClN4S	459	C1CN(CCN1C2=NC3=C(N4C2=CC=C4)SC=C3)C(C5=CC=CC=C5)C6=CC=C(C=C6)Cl	IC50 = 281838.29 nM	Non binder
T83813	5-HT 2C receptor	BQZC48	8-[4-[(5-Methoxy-3,4-dihydro-2H-chromen-3-yl)methylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione	Investigative	10409556	C24H34N2O4	414.5	COC1=CC=CC2=C1CC(CO2)CNCCCCN3C(=O)CC4(CCCC4)CC3=O	IC50 = 5890000000000000 nM	Non binder
T83813	5-HT 2C receptor	BR5Y7H	2-Ethyl-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepin-3-one	Investigative	14515723	C9H14N2O2	182.22	CCN1C(=O)C2=C(O1)CCNCC2	Ki = 300000 nM	Non binder
T83813	5-HT 2C receptor	BR9K8E	2-Methyl-4,5,6,7-tetrahydro-[1,2]oxazolo[4,5-c]pyridin-3-one	Investigative	71562664	C7H10N2O2	154.17	CN1C(=O)C2=C(O1)CCNC2	EC50 > 1000000 nM	Non binder
T83813	5-HT 2C receptor	BS48OP	3-Ethoxy-4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridine	Investigative	71562552	C8H12N2O2	168.19	CCOC1=NOC2=C1CCNC2	EC50 > 1000000 nM	Non binder
T83813	5-HT 2C receptor	BT6R0L	5-Methoxy-1',4'-dipropylspiro[2,4-dihydrochromene-3,2'-piperazine]	Investigative	44267158	C19H30N2O2	318.5	CCCN1CCN(C2(C1)CC3=C(C=CC=C3OC)OC2)CCC	IC50 = 33100000000000 nM	Non binder
T83813	5-HT 2C receptor	BV1E6H	5,6,7,8-Tetrahydro-4H-isoxazolo(4,5-d)azepin-3-ol	Investigative	171289	C7H10N2O2	154.17	C1CNCCC2=C1C(=O)NO2	Ki > 300000 nM	Non binder
T83813	5-HT 2C receptor	BWVU32	2,6-Dimethyl-4,5,7,8-tetrahydro-[1,2]oxazolo[4,5-d]azepin-3-one	Investigative	14515727	C9H14N2O2	182.22	CN1CCC2=C(CC1)ON(C2=O)C	Ki > 300000 nM	Non binder
T83813	5-HT 2C receptor	BZ3Y0O	8-[4-(5-Methoxy-4'-propylspiro[2,4-dihydrochromene-3,3'-piperazine]-1'-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione	Investigative	44267168	C29H43N3O4	497.7	CCCN1CCN(CC12CC3=C(C=CC=C3OC)OC2)CCCCN4C(=O)CC5(CCCC5)CC4=O	IC50 = 32400000000000 nM	Non binder