TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T82795 Beta-catenin B2R0ZK 4-Amino-N-isobutyl-1,2,5-oxadiazole-3-carboxamide Investigative 4417218 C7H12N4O2 184.2 CC(C)CNC(=O)C1=NON=C1N Ki > 2000000 nM Non binder T82795 Beta-catenin B4M3WQ 4-Amino-N-benzyl-1,2,5-oxadiazole-3-carboxamide Investigative 723206 C10H10N4O2 218.21 C1=CC=C(C=C1)CNC(=O)C2=NON=C2N Ki = 1700000 nM Non binder T82795 Beta-catenin B9PV5E (9Z)-9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one thiosemicarbazone Investigative 689303 C12H7N7OS 297.3 C1=CC=C2C(=C1)C(=C3C2=NC4=NONC4=N3)N=NC(=S)N Ki = 240000 nM Non binder T82795 Beta-catenin BH5XJ0 9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-E]pyrazin-9-one Investigative 568763 C11H4N4O2 224.17 C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O Ki = 310000 nM Non binder T82795 Beta-catenin BLXY38 3-[2-(1-Hydroxybenzotriazol-5-yl)ethyl]-2H-1,2,4-oxadiazol-5-one Investigative 136268330 C10H9N5O3 247.21 C1=CC2=C(C=C1CCC3=NOC(=O)N3)N=NN2O Ki = 551250 nM Non binder T82795 Beta-catenin BR0SV6 2-(13-Oxa-8,10,12,14,16-pentazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(16),2,4,6,9,11,14-heptaen-8-yl)acetic acid Investigative 122180637 C12H7N5O3 269.22 C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3N2CC(=O)O IC50 = 280000 nM Non binder T82795 Beta-catenin BR2U6K N\\N=C1\\c2Ccccc2-c2nc3nonc3nc12 Investigative 135995896 C11H6N6O 238.2 C1=CC=C2C(=C1)C(=C3C2=NC4=NONC4=N3)N=N Ki = 230000 nM Non binder T82795 Beta-catenin BS3E9A (S)-4-((S)-3-Carboxy-2-((S)-2-(2-(5-chloro-1H-indol-2-yl)acetamido)-3-(naphthalen-2-yl)propanamido)propanamido)-5-methoxy-5-oxopentanoic acid Investigative 90656496 C33H33ClN4O9 665.1 COC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)CC3=CC4=C(N3)C=CC(=C4)Cl IC50 = 210000 nM Non binder T82795 Beta-catenin BS98DP 1-Hydroxy-5-[2-(2H-tetrazol-5-yl)ethyl]indazole Investigative 71695771 C10H10N6O 230.23 C1=CC2=C(C=C1CCC3=NNN=N3)C=NN2O IC50 = 300000 nM Non binder T82795 Beta-catenin BX1W9N (4-Amino-1,2,5-oxadiazol-3-yl)(pyrrolidin-1-yl)methanone Investigative 673949 C7H10N4O2 182.18 C1CCN(C1)C(=O)C2=NON=C2N Ki = 1700000 nM Non binder T82795 Beta-catenin BX6FV4 3-(13-Oxa-8,10,12,14,16-pentazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(16),2,4,6,9,11,14-heptaen-8-yl)propanoic acid Investigative 122180639 C13H9N5O3 283.24 C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3N2CCC(=O)O IC50 = 580000 nM Non binder T82795 Beta-catenin BZQ81E 4-Amino-1,2,5-oxadiazole-3-carboxamide Investigative 541913 C3H4N4O2 128.09 C1(=NON=C1N)C(=O)N Ki > 2000000 nM Non binder T82795 Beta-catenin D07WDQ GNF-PF-67 Investigative 66541 C7H7N5O2 193.16 CN1C2=NC(=O)N(C(=O)C2=NC=N1)C IC50 = 340000 nM Non binder