TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T82514	Neurokinin receptor 2	B06TUA	Methyl 6-acetamido-3-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate	Investigative	57394644	C34H33F6N5O6	721.6	CC(=O)NC1CC(=C2CCC(N2C1=O)C(=O)N[C@@H](CCC3=CNC4=CC=CC=C43)C(=O)NCC5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F)C(=O)OC	Ki > 3000000 nM	Non binder
T82514	Neurokinin receptor 3	B0AS6C	n-Benzyl-7-methoxy-2-phenylquinoline-4-carboxamide	Investigative	10270385	C24H20N2O2	368.4	COC1=CC2=C(C=C1)C(=CC(=N2)C3=CC=CC=C3)C(=O)NCC4=CC=CC=C4	Ki = 533000 nM	Non binder
T82514	Neurokinin receptor 1	B0JZO5	(2S)-2-N-[(2R)-1-[Benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-(2-nitrophenyl)pyrrolidine-1,2-dicarboxamide	Investigative	10745788	C33H33N5O5	579.6	CN(CC1=CC=CC=C1)C(=O)[C@@H](CC2=CC3=CC=CC=C3C=C2)NC(=O)[C@@H]4CCCN4C(=O)NC5=CC=CC=C5[N+](=O)[O-]	IC50 = 274000 nM	Non binder
T82514	Neurokinin receptor 2	B67ESK	Methyl 6-acetamido-3-[[(2S)-1-[benzyl(methyl)amino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate	Investigative	57391132	C33H37N5O6	599.7	CC(=O)NC1CC(=C2CCC(N2C1=O)C(=O)N[C@@H](CCC3=CNC4=CC=CC=C43)C(=O)N(C)CC5=CC=CC=C5)C(=O)OC	Ki = 398000 nM	Non binder
T82514	Neurokinin receptor 1	BD0G5Y	Chembl4215185	Investigative	145971823	C26H17F3N4O5S	554.5	CC1=CC=C(C=C1)S(=O)C2=C(OC(=C([C@H]2C3=CC=C(C=C3)[N+](=O)[O-])C#N)NC(=O)C(F)(F)F)C4=CC=CC=N4	EC50 = 350000 nM	Non binder
T82514	Neurokinin receptor 2	BN0G8T	[3,5-Bis(trifluoromethyl)phenyl]methyl (2S)-3-(1H-indol-3-yl)-2-[[(2S)-4-methyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]pentanoyl]amino]propanoate	Investigative	57396389	C36H36F6N4O6	734.7	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)NC(=O)CNC(=O)OCC4=CC=CC=C4	Ki = 250000 nM	Non binder