TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T81386 Positive transcription elongation factor b B5BIW8 N-(2-(1H-Indol-3-yl)ethyl)-4-chloro-N-methylbenzamide Investigative 11515154 C18H17ClN2O 312.8 CN(CCC1=CNC2=CC=CC=C21)C(=O)C3=CC=C(C=C3)Cl IC50 > 1000000 nM Non binder T81386 Positive transcription elongation factor b BEKU58 N-(2-(1H-Indol-3-yl)ethyl)-N-methyl-[1,1'-biphenyl]-4-carboxamide Investigative 11610059 C24H22N2O 354.4 CN(CCC1=CNC2=CC=CC=C21)C(=O)C3=CC=C(C=C3)C4=CC=CC=C4 IC50 > 1000000 nM Non binder T81386 Positive transcription elongation factor b BH8K1G Chembl4216945 Investigative 145972145 C18H20N4O2 324.4 CCC(CC)C(=O)NC1=C2C=C(C=NC2=NN1)C3=CC=C(C=C3)O IC50 = 529300 nM Non binder T81386 Positive transcription elongation factor b BI7B0Y N-(2-(1H-Indol-3-yl)ethyl)-4-tert-butyl-N-methylbenzamide Investigative 11624162 C22H26N2O 334.5 CC(C)(C)C1=CC=C(C=C1)C(=O)N(C)CCC2=CNC3=CC=CC=C32 IC50 > 1000000 nM Non binder T81386 Positive transcription elongation factor b BT5DP3 Fascaplysine Investigative 73292 C18H11ClN2O 306.7 C1=CC=C2C(=C1)C3=C(N2)C4=[N+](C=C3)C5=CC=CC=C5C4=O.[Cl-] IC50 > 250000 nM Non binder