TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T79155	Kallikrein-7	B0CKA1	Tert-butyl N-[(2S)-1-[[(3S,3aR,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]carbamate	Investigative	76317473	C23H34N2O6S	466.6	CC(C)(C)OC(=O)N[C@@H](CCSC)C(=O)N[C@H]1CO[C@H]2[C@@H]1OC[C@H]2OCC3=CC=CC=C3	IC50 = 456800 nM	Non binder
T79155	Kallikrein-7	B8E4KZ	Benzyl (2S)-2-[[(2S)-1-[[(3S,3aR,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidine-1-carboxylate	Investigative	76317475	C35H39N3O7	613.7	C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@H]4CO[C@H]5[C@@H]4OC[C@H]5OCC6=CC=CC=C6	IC50 = 249300 nM	Non binder
T79155	Kallikrein-7	BA5WX1	Tert-butyl N-[(2R)-1-[[(3S,3aR,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate	Investigative	76317474	C29H35N3O6	521.6	CC(C)(C)OC(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H]3CO[C@H]4[C@@H]3OC[C@H]4OCC5=CC=CC=C5	IC50 = 418300 nM	Non binder
T79155	Kallikrein-7	BATK82	2-[[(3S,3Ar,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]-[2-(4-methoxyphenyl)acetyl]amino]-N-cyclohexyl-2-methylpropanamide	Investigative	134151146	C32H42N2O6	550.7	CC(C)(C(=O)NC1CCCCC1)N([C@H]2CO[C@H]3[C@@H]2OC[C@H]3OCC4=CC=CC=C4)C(=O)CC5=CC=C(C=C5)OC	IC50 = 272000 nM	Non binder
T79155	Kallikrein-7	BDT52U	N-[(3S,3Ar,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]-N-[1-(cyclohexylamino)-2-methyl-1-oxopropan-2-yl]benzamide	Investigative	134137014	C30H38N2O5	506.6	CC(C)(C(=O)NC1CCCCC1)N([C@H]2CO[C@H]3[C@@H]2OC[C@H]3OCC4=CC=CC=C4)C(=O)C5=CC=CC=C5	IC50 = 572000 nM	Non binder
T79155	Kallikrein-7	BH14DR	Tert-butyl N-[(2R)-1-[[(3S,3aR,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Investigative	76324824	C23H34N2O6	434.5	CC(C)[C@H](C(=O)N[C@H]1CO[C@H]2[C@@H]1OC[C@H]2OCC3=CC=CC=C3)NC(=O)OC(C)(C)C	IC50 > 1000000 nM	Non binder
T79155	Kallikrein-7	BX8YL3	2-[[(3S,3Ar,6R,6aS)-6-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]-[2-(4-hydroxyphenyl)acetyl]amino]-N-cyclohexyl-2-methylpropanamide	Investigative	134146409	C31H40N2O6	536.7	CC(C)(C(=O)NC1CCCCC1)N([C@H]2CO[C@H]3[C@@H]2OC[C@H]3OCC4=CC=CC=C4)C(=O)CC5=CC=C(C=C5)O	IC50 = 249000 nM	Non binder
T79155	Kallikrein-7	BXDR94	[(3R,3Ar,6R,6aR)-3-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] (2R)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate	Investigative	76328377	C23H33NO7	435.5	CC(C)[C@H](C(=O)O[C@@H]1CO[C@H]2[C@@H]1OC[C@H]2OCC3=CC=CC=C3)NC(=O)OC(C)(C)C	IC50 = 239000 nM	Non binder