TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T74977 Dual specificity protein kinase TTK B6L2UT 3-Amino-2-hydroxypyridine Investigative 322353 C5H6N2O 110.11 C1=CNC(=O)C(=C1)N Ki > 1000000 nM Non binder T74977 Dual specificity protein kinase TTK BG5SC2 Chembl4280041 Investigative 145980334 C14H17N3O 243.3 CN(C)CC1=CC=C(C=C1)C2=CNC(=O)C(=C2)N Ki = 367300 nM Non binder T74977 Dual specificity protein kinase TTK BVH0D3 5-Amino-1-methyl[3,4'-bipyridin]-6(1H)-one Investigative 23339828 C11H11N3O 201.22 CN1C=C(C=C(C1=O)N)C2=CC=NC=C2 Ki = 236400 nM Non binder T74977 Dual specificity protein kinase TTK BX0F5D Chembl4295011 Investigative 145993958 C9H8N4O 188.19 C1=C(C(=O)NC=C1C2=CN=CN=C2)N Ki = 269300 nM Non binder