TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B05GSJ	[1-[3-(4-Phenyltriazol-1-yl)propyl]piperidin-3-yl]methyl 2-phenylbenzoate	Investigative	57390895	C30H32N4O2	480.6	C1CC(CN(C1)CCCN2C=C(N=N2)C3=CC=CC=C3)COC(=O)C4=CC=CC=C4C5=CC=CC=C5	IC50 = 389045.14 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B1G8UQ	3-Cyclopropyl-3-(dimethylamino)propyl dimethylcarbamate	Investigative	44570101	C11H22N2O2	214.3	CN(C)C(CCOC(=O)N(C)C)C1CC1	EC50 = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B43EBR	3-(Dimethylamino)butyl 3-phenylpropylcarbamate	Investigative	44570057	C16H26N2O2	278.39	CC(CCOC(=O)NCCCC1=CC=CC=C1)N(C)C	EC50 = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B4DUO0	(1R,16R)-16-Methoxy-5-oxa-10-azatetracyclo[8.7.0.01,13.02,7]heptadeca-2(7),13-dien-4-one	Investigative	44354684	C16H21NO3	275.34	CO[C@@H]1CC=C2CCN3[C@@]2(C1)C4=C(CC3)COC(=O)C4	IC50 = 240000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B4IUM2	Methyl (3aR,5R,9bR)-7,9-dichloro-5-phenylsulfanyl-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-h]isoquinoline-1-carboxylate	Investigative	11211996	C19H18Cl2N2O2S	409.3	COC(=O)N1CC[C@H]2[C@@H]1C3=C(N=C(C=C3[C@@H](C2)SC4=CC=CC=C4)Cl)Cl	EC50 > 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B57QHB	(4As,10bR)-1,2,3,4,4a,5,6,10b-octahydro-1,9-phenanthroline	Investigative	44421466	C12H16N2	188.27	C1C[C@@H]2CCC3=C([C@@H]2NC1)C=NC=C3	EC50 > 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B5D3EM	3-(Dimethylamino)butyl 3-methylazetidine-1-carboxylate;oxalic acid	Investigative	49859909	C13H24N2O6	304.34	CC1CN(C1)C(=O)OCCC(C)N(C)C.C(=O)(C(=O)O)O	EC50 > 316227.77 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B7V3WA	Methyl (3aS,9bR)-9-chloro-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-h]isoquinoline-1-carboxylate	Investigative	11425617	C13H15ClN2O2	266.72	COC(=O)N1CC[C@H]2[C@@H]1C3=C(CC2)C=CN=C3Cl	EC50 > 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	B9WN5C	2alpha-[[[2-Methyl-5-(1-hexynyl)-3-pyridinyl]oxy]methyl]azetidine	Investigative	71525308	C16H22N2O	258.36	CCCCC#CC1=CC(=C(N=C1)C)OC[C@@H]2CCN2	Ki = 230000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BAQU58	Methyl (3aR,5R,9bR)-5-(benzenesulfonyl)-7,9-dichloro-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-h]isoquinoline-1-carboxylate	Investigative	11201533	C19H18Cl2N2O4S	441.3	COC(=O)N1CC[C@H]2[C@@H]1C3=C(N=C(C=C3[C@@H](C2)S(=O)(=O)C4=CC=CC=C4)Cl)Cl	EC50 > 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BDJU61	3-(Dimethylamino)-3-(thiophen-3-yl)propyl dimethylcarbamate	Investigative	44570102	C12H20N2O2S	256.37	CN(C)C(CCOC(=O)N(C)C)C1=CSC=C1	EC50 = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BJ1P2K	1-(3-(Dimethylamino)butyl)-3-phenylurea	Investigative	44570099	C13H21N3O	235.33	CC(CCNC(=O)NC1=CC=CC=C1)N(C)C	Ki = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BN07RM	3-(3-(Dimethylamino)butyl)-1,1-dimethylurea	Investigative	44570098	C9H21N3O	187.28	CC(CCNC(=O)N(C)C)N(C)C	Ki = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BP9A2N	2-Phenyl-N-[[1-(3-phenylpropyl)piperidin-3-yl]methyl]benzamide	Investigative	57396175	C28H32N2O	412.6	C1CC(CN(C1)CCCC2=CC=CC=C2)CNC(=O)C3=CC=CC=C3C4=CC=CC=C4	IC50 = 100000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BT5V6B	3-(Dimethylamino)-3-phenylpropyl dimethylcarbamate	Investigative	44570103	C14H22N2O2	250.34	CN(C)C(CCOC(=O)N(C)C)C1=CC=CC=C1	EC50 = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BU02KL	3-(Dimethylamino)butyl 4-cyanophenyl(methyl)carbamate	Investigative	44570007	C15H21N3O2	275.35	CC(CCOC(=O)N(C)C1=CC=C(C=C1)C#N)N(C)C	EC50 = 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BU43PR	5-(Dimethylamino)-N,N-dimethylhexanamide	Investigative	44570053	C10H22N2O	186.29	CC(CCCC(=O)N(C)C)N(C)C	Ki = 300000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BUK47Y	3-(Dimethylamino)butyl 2-hydroxyethylcarbamate	Investigative	44570012	C9H20N2O3	204.27	CC(CCOC(=O)NCCO)N(C)C	EC50 = 300000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BVU0X6	(5S)-Spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one	Investigative	5310971	C9H14N2O2	182.22	C1CN2CCC1[C@@]3(C2)CNC(=O)O3	IC50 > 1000000 nM	Non binder
T74166	Neuronal acetylcholine receptor alpha-3/beta-4	BW1O0Y	5-Hex-1-ynyl-2-methyl-3-[[(2R)-pyrrolidin-2-yl]methoxy]pyridine	Investigative	71584825	C17H24N2O	272.4	CCCCC#CC1=CC(=C(N=C1)C)OC[C@H]2CCCN2	Ki = 220000 nM	Non binder