TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T72458	Melanocortin receptor 4	B3GU7S	(R)-2-[(1H-Indol-3-ylmethyl)-amino]-3-naphthalen-2-yl-propionamide	Investigative	44265719	C22H21N3O	343.4	C1=CC=C2C=C(C=CC2=C1)C[C@H](C(=O)N)NCC3=CNC4=CC=CC=C43	Ki > 1000000 nM	Non binder
T72458	Melanocortin receptor 4	B4KSN6	N-(4-Aminobutyl)-N-isopropyl-1H-indole-3-carboxamide	Investigative	44434625	C16H23N3O	273.37	CC(C)N(CCCCN)C(=O)C1=CNC2=CC=CC=C21	Ki = 222000 nM	Non binder
T72458	Melanocortin receptor 4	B58VZA	(S)-2-[(1H-Indol-3-ylmethyl)-amino]-3-naphthalen-2-yl-propionamide	Investigative	44265708	C22H21N3O	343.4	C1=CC=C2C=C(C=CC2=C1)C[C@@H](C(=O)N)NCC3=CNC4=CC=CC=C43	Ki > 1000000 nM	Non binder
T72458	Melanocortin receptor 4	B6UD5G	3-(Piperazin-1-ylmethyl)-1H-indole	Investigative	17880880	C13H17N3	215.29	C1CN(CCN1)CC2=CNC3=CC=CC=C32	Ki > 1000000 nM	Non binder
T72458	Melanocortin receptor 4	BFR29T	N-(3-Guanidinopropyl)-1-(2-naphthylmethyl)-4alpha-hydroxy-L-prolinamide	Investigative	44265681	C20H27N5O2	369.5	C1[C@@H](CN([C@@H]1C(=O)NCCCN=C(N)N)CC2=CC3=CC=CC=C3C=C2)O	Ki = 279000 nM	Non binder
T72458	Melanocortin receptor 4	BKT82V	4-(1H-Indole-3-ylmethyl)-1-piperazinecarboxamidine	Investigative	44265225	C14H19N5	257.329	C1CN(CCN1CC2=CNC3=CC=CC=C32)C(=N)N	Ki > 1000000 nM	Non binder
T72458	Melanocortin receptor 4	BR42DX	(R)-5-Guanidino-2-[(naphthalen-2-ylmethyl)-amino]-pentanoic acid amide	Investigative	44265675	C17H23N5O	313.4	C1=CC=C2C=C(C=CC2=C1)CN[C@H](CCCN=C(N)N)C(=O)N	Ki > 1000000 nM	Non binder
T72458	Melanocortin receptor 4	BSU9D8	N-(1-Naphthylmethyl)-N-(2-naphthylmethyl)amine	Investigative	2817655	C22H19N	297.4	C1=CC=C2C=C(C=CC2=C1)CNCC3=CC=CC4=CC=CC=C43	Ki > 1000000 nM	Non binder
T72458	Melanocortin receptor 4	BSZO64	Nalpha-(1H-Indole-3-ylmethyl)-L-Arg-L-Trp-NH2	Investigative	44265656	C26H32N8O2	488.6	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N)NC(=O)[C@H](CCCN=C(N)N)NCC3=CNC4=CC=CC=C43	Ki = 205000 nM	Non binder
T72458	Melanocortin receptor 4	BZYD45	1-(Naphthalen-2-ylmethyl)piperazine	Investigative	910537	C15H18N2	226.32	C1CN(CCN1)CC2=CC3=CC=CC=C3C=C2	Ki > 1000000 nM	Non binder