TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T69685	Glycine transporter GlyT-1	B0SGR2	2,4-Dichloro-N-[[(1S,5R)-3-(1-methylimidazol-4-yl)sulfonyl-6-pyridin-2-yl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide	Investigative	76328675	C22H21Cl2N5O3S	506.4	CN1C=C(N=C1)S(=O)(=O)N2C[C@@H]3[C@H](C2)C3(CNC(=O)C4=C(C=C(C=C4)Cl)Cl)C5=CC=CC=N5	IC50 = 247000 nM	Non binder
T69685	Glycine transporter GlyT-1	B32UQD	CID 46239503	Investigative	46239503	C18H21FN4O3S	392.4	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC=CC=C4F	IC50 = 1815000 nM	Non binder
T69685	Glycine transporter GlyT-1	B35JEB	2,4-Dichloro-N-[[1-(4-propylsulfonylpiperazin-1-yl)-2,3-dihydroinden-1-yl]methyl]benzamide	Investigative	71718695	C24H29Cl2N3O3S	510.5	CCCS(=O)(=O)N1CCN(CC1)C2(CCC3=CC=CC=C32)CNC(=O)C4=C(C=C(C=C4)Cl)Cl	IC50 = 6400000 nM	Non binder
T69685	Glycine transporter GlyT-1	B64XCA	CID 46239507	Investigative	46239507	C18H20F2N4O3S	410.4	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC(=C(C=C4)F)F	IC50 = 1569000 nM	Non binder
T69685	Glycine transporter GlyT-1	B65ZYR	2,4-Dichloro-N-(phenyl(1-(propylsulfonyl)azetidin-3-yl)methyl)benzamide	Investigative	46935693	C20H22Cl2N2O3S	441.4	CCCS(=O)(=O)N1CC(C1)C(C2=CC=CC=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 = 627000 nM	Non binder
T69685	Glycine transporter GlyT-1	B6H2JW	2,4-Dichloro-N-[[1-(1-methylimidazol-4-yl)sulfonylpiperidin-4-yl]-phenylmethyl]benzamide	Investigative	46938092	C23H24Cl2N4O3S	507.4	CN1C=C(N=C1)S(=O)(=O)N2CCC(CC2)C(C3=CC=CC=C3)NC(=O)C4=C(C=C(C=C4)Cl)Cl	IC50 = 201000 nM	Non binder
T69685	Glycine transporter GlyT-1	B8ZIN0	4-({4-(4-Fluorophenyl)-3-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-pyrazol-1-yl}sulfonyl)-1-methyl-1H-1,2,3-triazole	Investigative	118937481	C19H15F4N5O2S	453.4	CN1C=C(N=N1)S(=O)(=O)N2CC(C(=N2)C3=CC(=CC=C3)C(F)(F)F)C4=CC=C(C=C4)F	Ki <= 10000000 nM	Non binder
T69685	Glycine transporter GlyT-1	B95ARM	N-[2-(1-Methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]cyclohexanecarboxamide	Investigative	46239508	C18H28N4O3S	380.5	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4CCCCC4	IC50 = 617000 nM	Non binder
T69685	Glycine transporter GlyT-1	B97MZF	CID 46239505	Investigative	46239505	C18H21FN4O3S	392.4	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC=C(C=C4)F	IC50 = 2215000 nM	Non binder
T69685	Glycine transporter GlyT-1	BE29ZT	2,6-Difluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide	Investigative	46239506	C18H20F2N4O3S	410.4	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=C(C=CC=C4F)F	IC50 = 631000 nM	Non binder
T69685	Glycine transporter GlyT-1	BK25JG	CID 46213935	Investigative	46213935	C18H21ClN4O3S	408.9	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC=C(C=C4)Cl	IC50 = 1029000 nM	Non binder
T69685	Glycine transporter GlyT-1	BKG2B8	3-Fluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide	Investigative	76314241	C18H21FN4O3S	392.4	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC(=CC=C4)F	IC50 > 10000000 nM	Non binder
T69685	Glycine transporter GlyT-1	BM2R4N	CN1N=CC(=C1)S(=O)(=O)N1N=C(C(C1)C1=CC=CC=C1)C1=NC=CC=C1	Investigative	118937507	C18H17N5O2S	367.4	CN1C=C(C=N1)S(=O)(=O)N2CC(C(=N2)C3=CC=CC=N3)C4=CC=CC=C4	Ki >= 10000000 nM	Non binder
T69685	Glycine transporter GlyT-1	BM71GD	CID 46239504	Investigative	46239504	C18H20Cl2N4O3S	443.3	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC(=C(C=C4)Cl)Cl	IC50 = 891000 nM	Non binder
T69685	Glycine transporter GlyT-1	BP0K8G	2,4-Dichloro-N-[[1-(1-methylimidazol-4-yl)sulfonylpiperidin-4-yl]-thiophen-2-ylmethyl]benzamide	Investigative	46938152	C21H22Cl2N4O3S2	513.5	CN1C=C(N=C1)S(=O)(=O)N2CCC(CC2)C(C3=CC=CS3)NC(=O)C4=C(C=C(C=C4)Cl)Cl	IC50 = 374000 nM	Non binder
T69685	Glycine transporter GlyT-1	BUL48C	2,4-Dichloro-N-[phenyl-(1-propylsulfonylpiperidin-4-yl)methyl]benzamide	Investigative	46938091	C22H26Cl2N2O3S	469.4	CCCS(=O)(=O)N1CCC(CC1)C(C2=CC=CC=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 = 1500000 nM	Non binder
T69685	Glycine transporter GlyT-1	BVEI98	2,4-Difluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide	Investigative	46239402	C18H20F2N4O3S	410.4	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=C(C=C(C=C4)F)F	IC50 = 926000 nM	Non binder
T69685	Glycine transporter GlyT-1	BWH6M8	Ethyl N-[1-[(3-chlorophenyl)methyl]-7-[2-[[1-(difluoromethyl)pyrazol-4-yl]sulfonylamino]ethoxy]-1,2,3,4-tetrahydronaphthalen-2-yl]carbamate	Investigative	59547790	C26H29ClF2N4O5S	583	CCOC(=O)NC1CCC2=C(C1CC3=CC(=CC=C3)Cl)C=C(C=C2)OCCNS(=O)(=O)C4=CN(N=C4)C(F)F	IC50 > 1000000 nM	Non binder
T69685	Glycine transporter GlyT-1	D0X3CF	HINOKININ	Investigative	442879	C20H18O6	354.4	C1[C@@H]([C@H](C(=O)O1)CC2=CC3=C(C=C2)OCO3)CC4=CC5=C(C=C4)OCO5	IC50 > 500000 nM	Non binder