TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67363	Integrin alpha-V/beta-3	B0OWK3	Arg-Gly-Asp-Arg-Gly-Asp	Investigative	10032445	C24H42N12O11	674.7	C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O)N)CN=C(N)N	IC50 = 619000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B24EBN	Ethyl 2-[benzyl-[(2S)-2-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid	Investigative	71654376	C29H28F3N3O8	603.5	CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)O[C@H](CO3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B2DTK4	3-[(3S,6S,12S,15S,21S,24S,30S,36S,39S,42S)-6,15,24-Tris(carboxymethyl)-12,21,30-tris[3-(diaminomethylideneamino)propyl]-36-[(1R)-1-hydroxyethyl]-3-(2-methylpropyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41-tetradecaoxo-1,4,7,10,13,16,19,22,25,28,31,34,37,40-tetradecazabicyclo[40.3.0]pentatetracontan-39-yl]propanoic acid	Investigative	137632555	C58H95N23O23	1482.5	C[C@H]([C@H]1C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N1)CCC(=O)O)CC(C)C)CC(=O)O)CCCN=C(N)N)CC(=O)O)CCCN=C(N)N)CC(=O)O)CCCN=C(N)N)O	IC50 = 257000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B37FHW	2-Benzyloxycarbonylamino-3-[4-(3-tert-butylamino-2-hydroxy-propoxy)-phenyl]-propionic acid	Investigative	15030977	C24H32N2O6	444.5	CC(C)(C)NCC(COC1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)OCC2=CC=CC=C2)O	IC50 > 300000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B3MA8R	4-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)amino)-4-oxobutanoic acid	Investigative	44436710	C27H32N4O4	476.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)CCC(=O)O	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B3ON5R	1-(2-Chlorophenyl)biguanide	Investigative	29669	C8H10ClN5	211.65	C1=CC=C(C(=C1)N=C(N)N=C(N)N)Cl	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B3RN5S	2-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)carbamoyl)-4-methoxy-4-oxobutanoic acid	Investigative	44436711	C29H34N4O6	534.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)OC)C(=O)O	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B42MKT	2-({1-[(4-Aminophenyl)methyl]-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl}(propyl)carbamoyl)butanedioic acid	Investigative	44436715	C27H31N3O6	493.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)O)C(=O)O	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B4A2OQ	3-(3-(3-Amino-N-propylpropanamido)-4-methyl-2-oxo-6-phenyl-5,6-dihydropyridin-1(2H)-yl)propanoic acid	Investigative	44436701	C21H29N3O4	387.5	CCCN(C1=C(CC(N(C1=O)CCC(=O)O)C2=CC=CC=C2)C)C(=O)CCN	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B5FA7L	3-(3-(6-Amino-N-propylhexanamido)-4-methyl-2-oxo-6-phenyl-5,6-dihydropyridin-1(2H)-yl)propanoic acid	Investigative	44436703	C24H35N3O4	429.6	CCCN(C1=C(CC(N(C1=O)CCC(=O)O)C2=CC=CC=C2)C)C(=O)CCCCCN	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B5Q7BV	Ethyl 2-[benzyl-[(2R)-2-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid	Investigative	71654374	C29H28F3N3O8	603.5	CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)O[C@@H](CO3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B7PGR6	Ethyl 2-[benzyl-[(3R)-3-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid	Investigative	71654530	C29H28F3N3O8	603.5	CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)OC[C@H](O3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	B8CSA6	2-[Benzyl-[(2S)-2-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetic acid	Investigative	71654535	C25H23N3O6	461.5	C1[C@@H](OC2=C(O1)C=C(C=C2)N(CC3=CC=CC=C3)C(=O)C(=O)O)COC4=CC=C(C=C4)C(=N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BAZ2O1	N-{6-(4-Carbamimidoyl-phenyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-4-methyl-2-oxo-1,2,5,6-tetrahydro-pyridin-3-yl}-N-propyl-malonamic acid	Investigative	44436708	C28H34N4O5	506.6	CCCN(C1=C(CC(N(C1=O)[C@@H](C)C2=CC=C(C=C2)OC)C3=CC=C(C=C3)C(=N)N)C)C(=O)CC(=O)O	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BEI4C1	2-[Benzyl-[(3R)-3-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetic acid	Investigative	71654536	C25H23N3O6	461.5	C1[C@H](OC2=C(O1)C=CC(=C2)N(CC3=CC=CC=C3)C(=O)C(=O)O)COC4=CC=C(C=C4)C(=N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BF5J6Z	(S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid	Investigative	9870468	C22H22Cl2N2O5S	497.4	CC(=O)N1CSC[C@@H]1C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=C(C=CC=C3Cl)Cl)C(=O)O	IC50 > 800000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BH1Q5O	N-(5-Chloro-2-methylphenyl)imidodicarbonimidic diamide	Investigative	2969603	C9H12ClN5	225.68	CC1=C(C=C(C=C1)Cl)N=C(N)N=C(N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BH5SB4	N-[2-(Methylthio)phenyl]imidodicarbonimidic diamide	Investigative	2730204	C9H13N5S	223.3	CSC1=CC=CC=C1N=C(N)N=C(N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BIG5P3	Ethyl 3-{[{[amino(imino)methyl]amino}(imino)methyl]amino}benzoate	Investigative	6342934	C11H15N5O2	249.27	CCOC(=O)C1=CC(=CC=C1)N=C(N)N=C(N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BJVQ52	2-[(1R,6S,7R,8S,9R,23S,24R,25S)-19-[3-(Diaminomethylideneamino)propyl]-7,8,24,25-tetrahydroxy-4,12,15,18,21-pentaoxo-26,27-dioxa-3,11,14,17,20-pentazatricyclo[21.2.1.16,9]heptacosan-13-yl]acetic acid	Investigative	44341096	C26H42N8O13	674.7	C1[C@H]2[C@@H]([C@@H]([C@H](O2)CNC(=O)C(NC(=O)CNC(=O)C(NC(=O)C[C@H]3[C@@H]([C@@H]([C@H](O3)CNC1=O)O)O)CCCN=C(N)N)CC(=O)O)O)O	IC50 = 597000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BKOZ83	Ethyl 2-[benzyl-[(3S)-3-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid	Investigative	71654532	C29H28F3N3O8	603.5	CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)OC[C@@H](O3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BMBD37	2-[Benzyl-[(3S)-3-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetic acid	Investigative	71652207	C25H23N3O6	461.5	C1[C@@H](OC2=C(O1)C=CC(=C2)N(CC3=CC=CC=C3)C(=O)C(=O)O)COC4=CC=C(C=C4)C(=N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BMR60P	2-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)carbamoyl)succinic acid	Investigative	44436712	C28H32N4O6	520.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)O)C(=O)O	IC50 > 1000000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BNM57R	N-[3-(Methylthio)phenyl]imidodicarbonimidic diamide	Investigative	6342932	C9H13N5S	223.3	CSC1=CC=CC(=C1)N=C(N)N=C(N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BP3V0S	2-[Benzyl-[(2R)-2-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetic acid	Investigative	71654534	C25H23N3O6	461.5	C1[C@H](OC2=C(O1)C=C(C=C2)N(CC3=CC=CC=C3)C(=O)C(=O)O)COC4=CC=C(C=C4)C(=N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BQI2D1	(S)-N-Benzyl-3-{[(R)-1-(5-guanidino-pentanoyl)-pyrrolidine-2-carbonyl]-amino}-succinamic acid	Investigative	44439577	C22H32N6O5	460.5	C1C[C@@H](N(C1)C(=O)CCCCN=C(N)N)C(=O)N[C@@H](CC(=O)O)C(=O)NCC2=CC=CC=C2	IC50 = 230000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BY2IB0	N-(2-Ethoxyphenyl)imidodicarbonimidic diamide	Investigative	2943054	C10H15N5O	221.26	CCOC1=CC=CC=C1N=C(N)N=C(N)N	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	BZV41N	[1-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetylamino}-pentanoyl)-piperidin-2-yl]-acetic acid	Investigative	9828131	C29H38N4O5	522.6	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N[C@@H](CC(C)C)C(=O)N3CCCCC3CC(=O)O	IC50 > 200000 nM	Non binder
T67363	Integrin alpha-V/beta-3	D0H4NK	1-phenylbiguanide	Investigative	4780	C8H11N5	177.21	C1=CC=C(C=C1)N=C(N)N=C(N)N	IC50 > 200000 nM	Non binder