TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T66252 Dipeptidyl peptidase 9 D0M6CN US8470836, 5 Patented 44126186 C21H26F5N5O3 491.5 C1CC(C1)C2=NC3=C(CCN(C3)C(=O)C[C@@H](CN4C(C(CCC4=O)(F)F)O)N)C(=N2)C(F)(F)F IC50 > 400000 nM Non binder T66252 Dipeptidyl peptidase 9 D0S8CH US8470836, 2 Patented 42635875 C18H19F8N5O3 505.4 C1CC([C@@H](N(C1=O)C[C@H](CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C(F)(F)F)N)O)(F)F IC50 > 400000 nM Non binder T66252 Dipeptidyl peptidase 9 B2DY5F (6S)-1-[(2S)-2-Amino-4-[2-(2-methoxyethyl)-4-(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoro-6-hydroxypiperidin-2-one Investigative 44126292 C20H26F5N5O4 495.4 COCCC1=NC2=C(CCN(C2)C(=O)C[C@@H](CN3[C@H](C(CCC3=O)(F)F)O)N)C(=N1)C(F)(F)F IC50 > 210000 nM Non binder T66252 Dipeptidyl peptidase 9 B4Y5RQ Ala-boroPro Investigative 10149048 C7H15BN2O3 186.02 B([C@@H]1CCCN1C(=O)[C@H](C)N)(O)O IC50 = 360000 nM Non binder T66252 Dipeptidyl peptidase 9 BI3VQ6 (2S)-1-[(2S)-2-Amino-3-(furan-3-yl)propanoyl]pyrrolidine-2-carbonitrile Investigative 76325642 C12H15N3O2 233.27 C1C[C@H](N(C1)C(=O)[C@H](CC2=COC=C2)N)C#N IC50 > 288200 nM Non binder T66252 Dipeptidyl peptidase 9 BXLH78 Chembl4162340 Investigative 145958227 C19H19FN6O 366.4 C1C[C@H](CN(C1)C2=NC3=C(C(=O)N2CC4=C(C=CC(=C4)F)C#N)NC=C3)N IC50 > 300000 nM Non binder