TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T64725 Fatty acid desaturase 2 D0S0RS MK-8245 Phase 2 24988881 C17H16BrFN6O4 467.2 C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O IC50 > 100000000 nM Non binder T64725 Fatty acid desaturase 2 B0RNZ6 4-(2-Bromo-5-fluorophenoxy)-1-[5-(2H-tetrazol-5-yl)-1,3,4-thiadiazol-2-yl]piperidine Investigative 53388366 C14H13BrFN7OS 426.27 C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NN=C(S3)C4=NNN=N4 IC50 > 100000000 nM Non binder T64725 Fatty acid desaturase 2 BJC70Y 1-[5-(2H-Tetrazol-5-yl)-1,3,4-thiadiazol-2-yl]-4-[2-(trifluoromethyl)phenoxy]piperidine Investigative 15980639 C15H14F3N7OS 397.4 C1CN(CCC1OC2=CC=CC=C2C(F)(F)F)C3=NN=C(S3)C4=NNN=N4 IC50 > 100000000 nM Non binder T64725 Fatty acid desaturase 2 BN49QM MF-438 Investigative 16042458 C19H18F3N5OS 421.4 CC1=NN=C(S1)C2=NN=C(C=C2)N3CCC(CC3)OC4=CC=CC=C4C(F)(F)F IC50 > 100000000 nM Non binder T64725 Fatty acid desaturase 2 BP7VY6 2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid Investigative 24988880 C16H15BrFN7O3S 484.3 C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NN=C(S3)C4=NN(N=N4)CC(=O)O IC50 > 100000000 nM Non binder