TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T63512 Extracellular lysophospholipase D B3LUR8 3-(4H-[1,2,4]Triazol-3-yl)-phenylamine Investigative 6484188 C8H8N4 160.18 C1=CC(=CC(=C1)N)C2=NC=NN2 IC50 = 251188.64 nM Non binder T63512 Extracellular lysophospholipase D B3XH8Y [(2S,3S)-4-[4-[(3,5-Dimethylpyridin-2-yl)methoxy]phenyl]-3-(hexadecanoylamino)-2-hydroxybutyl]phosphonic acid Investigative 53323231 C34H55N2O6P 618.8 CCCCCCCCCCCCCCCC(=O)N[C@@H](CC1=CC=C(C=C1)OCC2=C(C=C(C=N2)C)C)[C@@H](CP(=O)(O)O)O Ki = 399000 nM Non binder T63512 Extracellular lysophospholipase D BF30KN 1H-Indole-6-carboxylic acid Investigative 595230 C9H7NO2 161.16 C1=CC(=CC2=C1C=CN2)C(=O)O IC50 = 794328.23 nM Non binder T63512 Extracellular lysophospholipase D BG3IN1 4-(Methylsulfonyl)phenol Investigative 123350 C7H8O3S 172.2 CS(=O)(=O)C1=CC=C(C=C1)O IC50 = 630957.34 nM Non binder T63512 Extracellular lysophospholipase D BL7X9I 3-(Aminomethyl)phenol Investigative 735894 C7H9NO 123.15 C1=CC(=CC(=C1)O)CN IC50 = 1258925.41 nM Non binder T63512 Extracellular lysophospholipase D BP6J4V [(2S,3S)-4-[4-[(3,5-Dimethylphenyl)methoxy]phenyl]-3-(hexadecanoylamino)-2-hydroxybutyl]phosphonic acid Investigative 53323167 C35H56NO6P 617.8 CCCCCCCCCCCCCCCC(=O)N[C@@H](CC1=CC=C(C=C1)OCC2=CC(=CC(=C2)C)C)[C@@H](CP(=O)(O)O)O Ki = 217500 nM Non binder T63512 Extracellular lysophospholipase D BZ45JX [(2S,3S)-4-[4-[(2,4-Dichlorophenyl)methoxy]phenyl]-3-(hexadecanoylamino)-2-hydroxybutyl]phosphonic acid Investigative 53321850 C33H50Cl2NO6P 658.6 CCCCCCCCCCCCCCCC(=O)N[C@@H](CC1=CC=C(C=C1)OCC2=C(C=C(C=C2)Cl)Cl)[C@@H](CP(=O)(O)O)O Ki = 1059200 nM Non binder T63512 Extracellular lysophospholipase D D0W6VA 4-(1H-IMIDAZOL-1-YL)PHENOL Investigative 82315 C9H8N2O 160.17 C1=CC(=CC=C1N2C=CN=C2)O IC50 = 501187.23 nM Non binder