TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T62391	Glutamate receptor AMPA 3	B2WLD9	(3S,4Ar,6S,8aR)-6-[(4-carboxyimidazol-1-yl)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid;dihydrochloride	Investigative	45262167	C15H23Cl2N3O4	380.3	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CN3C=C(N=C3)C(=O)O)C(=O)O.Cl.Cl	Ki = 247000 nM	Non binder
T62391	Glutamate receptor AMPA 3	B3T4OA	2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid	Investigative	10658567	C8H10N6O4	254.2	CN1C(=NN=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	EC50 > 3000000 nM	Non binder
T62391	Glutamate receptor AMPA 3	B3Z4CI	(RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid	Investigative	11219775	C10H14N6O4	282.26	CCCN1N=C(N=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	EC50 = 450000 nM	Non binder
T62391	Glutamate receptor AMPA 3	B7SB9O	(RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid	Investigative	16659202	C14H14N6O4	330.3	C1=CC=C(C=C1)CN2N=C(N=N2)C3=C(C(=O)NO3)CC(C(=O)O)N	EC50 = 1000000 nM	Non binder
T62391	Glutamate receptor AMPA 3	B95TLY	2-Amino-3-(3-hydroxy-5-(2-isopropyl-2H-tetrazol-5-yl)isoxazol-4-yl)propanoic acid	Investigative	11818375	C10H14N6O4	282.26	CC(C)N1N=C(N=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	EC50 = 700000 nM	Non binder
T62391	Glutamate receptor AMPA 3	BCZY82	2-Amino-3-(5-(2-ethyl-2H-tetrazol-5-yl)-3-hydroxyisoxazol-4-yl)propanoic acid	Investigative	11288627	C9H12N6O4	268.23	CCN1N=C(N=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	EC50 = 63100000000000 nM	Non binder
T62391	Glutamate receptor AMPA 3	BH7NR6	2-Amino-3-(4-bromo-3-hydroxyisoxazol-5-YL)propanoic acid	Investigative	2733518	C6H7BrN2O4	251.03	C(C1=C(C(=O)NO1)Br)C(C(=O)O)N	EC50 = 202000 nM	Non binder
T62391	Glutamate receptor AMPA 3	BY5D3O	Cl-HIBO	Investigative	4694356	C6H7ClN2O4	206.58	C(C1=C(C(=O)NO1)Cl)C(C(=O)O)N	EC50 = 2700000 nM	Non binder