TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T56496 Phenylethanolamine N-methyltransferase B6F7EB 2-Thiophenemethylamine Investigative 34005 C5H7NS 113.18 C1=CSC(=C1)CN Ki = 450000 nM Non binder T56496 Phenylethanolamine N-methyltransferase B98TOB 3-(Fluoromethyl)-N-(3-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide Investigative 11257061 C16H16FN3O4S 365.4 C1C(NCC2=C1C=CC(=C2)S(=O)(=O)NC3=CC(=CC=C3)[N+](=O)[O-])CF Ki = 250000 nM Non binder T56496 Phenylethanolamine N-methyltransferase B9OEP5 (1S)-1-Phenylethanamine Investigative 75818 C8H11N 121.18 C[C@@H](C1=CC=CC=C1)N Ki = 430000 nM Non binder T56496 Phenylethanolamine N-methyltransferase BEK2C4 N-(3-Chlorophenyl)-3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide Investigative 11439655 C16H16ClFN2O2S 354.8 C1C(NCC2=C1C=CC(=C2)S(=O)(=O)NC3=CC(=CC=C3)Cl)CF Ki = 890000 nM Non binder T56496 Phenylethanolamine N-methyltransferase BF1M9D (1R)-1-Phenylethanamine Investigative 643189 C8H11N 121.18 C[C@H](C1=CC=CC=C1)N Ki = 4800000 nM Non binder T56496 Phenylethanolamine N-methyltransferase BFM87V Thiophene-2-ethylamine Investigative 116521 C6H9NS 127.21 C1=CSC(=C1)CCN Ki = 300000 nM Non binder T56496 Phenylethanolamine N-methyltransferase BP3Z8T 1-Phenylethylamine Investigative 7408 C8H11N 121.18 CC(C1=CC=CC=C1)N Ki = 830000 nM Non binder T56496 Phenylethanolamine N-methyltransferase BP4QJ9 2-Aminobenzonorbornene Investigative 93889 C11H13N 159.23 C1C2CC(C1C3=CC=CC=C23)N Ki = 730000 nM Non binder T56496 Phenylethanolamine N-methyltransferase BY8JE5 9H-Fluorene-2-methanamine Investigative 21687108 C14H13N 195.26 C1C2=CC=CC=C2C3=C1C=C(C=C3)CN Ki = 530000 nM Non binder T56496 Phenylethanolamine N-methyltransferase D06CMJ Para-chloroamphetamine Investigative 3127 C9H12ClN 169.65 CC(CC1=CC=C(C=C1)Cl)N IC50 = 300000 nM Non binder