TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T53251	Histone-lysine N-methyltransferase EHMT2	B0TGQ3	CID 46902073	Investigative	46902073	C23H36N6O2	428.6	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N(C)C4CCN(CC4)C)OC)OC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	B0ZT1B	N-Isopropyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine	Investigative	44604817	C19H29N5O2	359.5	CC(C)NC1=NC(=NC2=CC(=C(C=C21)OC)OC)N3CCCN(CC3)C	IC50 = 5800000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	B40KBS	Tert-Butyl 4-(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-(1-methylpiperidin-4-ylamino)quinazolin-7-yloxy)butylcarbamate	Investigative	46901786	C30H49N7O4	571.8	CC(C)(C)OC(=O)NCCCCOC1=C(C=C2C(=C1)N=C(N=C2NC3CCN(CC3)C)N4CCCN(CC4)C)OC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	B7BG8Q	7-[6-(Dimethylamino)hexoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine	Investigative	46901455	C29H49N7O2	527.7	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCCCCN(C)C	IC50 = 3200000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	B7GOL5	N2,N2-Diethyl-6,7-dimethoxy-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine	Investigative	44605027	C20H31N5O2	373.5	CCN(CC)C1=NC2=CC(=C(C=C2C(=N1)NC3CCN(CC3)C)OC)OC	IC50 = 910000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	B7QOF4	6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-7-(4-methylpentoxy)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine	Investigative	46901625	C27H44N6O2	484.7	CC(C)CCCOC1=C(C=C2C(=C1)N=C(N=C2NC3CCN(CC3)C)N4CCCN(CC4)C)OC	IC50 = 3400000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	B8RAE4	6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine	Investigative	46901624	C28H45N7O3	527.7	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCN5CCOCC5	IC50 = 780000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BCDJ56	5-(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-(1-methylpiperidin-4-ylamino)quinazolin-7-yloxy)pentanamide	Investigative	46901788	C26H41N7O3	499.6	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCCC(=O)N	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BE2OI7	6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine	Investigative	44605028	C18H27N5O2	345.4	CN1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)N(C)C	IC50 = 900000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BFO2I9	6,7-Dimethoxy-N-(1-Methylpiperidin-4-Yl)-2-(Morpholin-4-Yl)quinazolin-4-Amine	Investigative	44605026	C20H29N5O3	387.5	CN1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)N4CCOCC4	IC50 = 810000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BH1LR6	CID 46901936	Investigative	46901936	C27H43N7O2	497.7	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCC5CCCNC5	IC50 = 1500000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BH6GS5	6,7-Dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine	Investigative	44604812	C22H34N6O2	414.5	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OC	IC50 = 230000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BKCV89	6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperidin-1-yl)quinazolin-4-amine	Investigative	44605025	C21H31N5O2	385.5	CN1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)N4CCCCC4	IC50 = 510000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BNE3R9	6,7-Dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(tetrahydro-2H-pyran-4-yl)quinazolin-4-amine	Investigative	44604814	C21H31N5O3	401.5	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCOCC4)OC)OC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BP57BU	N-Cyclohexyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine	Investigative	44604815	C22H33N5O2	399.5	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCCCC4)OC)OC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BS9GD0	6,7-Dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(piperidin-4-yl)quinazolin-4-amine	Investigative	44604813	C21H32N6O2	400.5	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCNCC4)OC)OC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BT8MJ6	CID 46901785	Investigative	46901785	C26H42N6O3	486.6	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCCOC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BW18TB	6,7-Dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-(1-methylpiperidin-4-yloxy)quinazoline	Investigative	46902074	C22H33N5O3	415.5	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)OC4CCN(CC4)C)OC)OC	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BWP9V0	2-Chloro-6,7-dimethoxy-N-(1-methylpiperidin-4-yl)quinazolin-4-amine	Investigative	44605029	C16H21ClN4O2	336.81	CN1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)Cl	IC50 = 9100000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BX10GN	6,7-Dimethoxy-N-methyl-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine	Investigative	46899644	C17H25N5O2	331.4	CNC1=NC(=NC2=CC(=C(C=C21)OC)OC)N3CCCN(CC3)C	IC50 > 10000000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BY6L7X	6,7-Dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpyrrolidin-3-yl)quinazolin-4-amine	Investigative	46899643	C21H32N6O2	400.5	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(C4)C)OC)OC	IC50 = 910000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	BZY2O1	N-Cyclopropyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine	Investigative	44604816	C19H27N5O2	357.4	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CC4)OC)OC	IC50 = 5100000 nM	Non binder
T53251	Histone-lysine N-methyltransferase EHMT2	D00FLT	Sinefungin	Investigative	65482	C15H23N7O5	381.39	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O)N	IC50 = 509000 nM	Non binder