TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T50970	Endothelin-converting enzyme 1	B6XEU9	(2S)-2-[[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	44301788	C19H25N3O5	375.4	CC(C)CC(CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	B8F9UN	3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxyamide	Investigative	10854279	C17H21NO4S	335.4	CCCCC(CC(=O)NO)S(=O)(=O)C1=CC2=CC=CC=C2C=C1	IC50 = 450000 nM	Non binder
T50970	Endothelin-converting enzyme 1	B9GSL6	(2S)-2-[[(2S)-2-[Ethoxy(hydroxy)phosphoryl]oxy-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	10432581	C19H27N2O7P	426.4	CCOP(=O)(O)O[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	BCJ1M5	2-[[(1S)-1-Carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl]-4-methylpentanoic acid	Investigative	44301373	C18H22N2O5	346.4	CC(C)CC(C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	BDQF53	(2S)-2-[[2-(Hydroxymethyl)-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	44301525	C18H24N2O4	332.4	CC(C)CC(CO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	BE54QO	(2S)-2-[[(2S)-2-[Hydroxy(propyl)phosphoryl]oxy-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	10432455	C20H29N2O6P	424.4	CCCP(=O)(O)O[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	BK6R1P	(2S)-2-[[(2S)-2-[[Hydroxy(propyl)phosphoryl]methyl]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	10093695	C21H31N2O5P	422.5	CCCP(=O)(C[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	BSUZ31	(2S)-2-[[(2S)-2-[[Ethoxy(hydroxy)phosphoryl]methyl]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	44294639	C20H29N2O6P	424.4	CCOP(=O)(C[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)O	IC50 ~ 100000 nM	Non binder
T50970	Endothelin-converting enzyme 1	BWK76T	(2S)-3-(1H-Indol-3-yl)-2-[[4-methyl-2-(2-sulfanylethyl)pentanoyl]amino]propanoic acid	Investigative	44301771	C19H26N2O3S	362.5	CC(C)CC(CCS)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O	IC50 ~ 100000 nM	Non binder