TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T50773	Dipeptidyl-peptidase 7	D0R9HL	Vildagliptin/metformin	Phase 3	11077541	C17H25N3O2	303.4	C1C[C@H](N(C1)C(=O)CNC23C[C@H]4C[C@@H](C2)CC(C4)(C3)O)C#N	IC50 = 210000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B0ZB5V	(S)-2,6-Diamino-1-(3,4-dihydroquinolin-1(2H)-yl)hexan-1-one	Investigative	44560929	C15H23N3O	261.36	C1CC2=CC=CC=C2N(C1)C(=O)[C@H](CCCCN)N	IC50 = 393000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B26FCE	(S)-Benzyl 5-amino-6-(3,4-dihydroquinolin-1(2H)-yl)-6-oxohexylcarbamate	Investigative	15101668	C23H29N3O3	395.5	C1CC2=CC=CC=C2N(C1)C(=O)[C@H](CCCCNC(=O)OCC3=CC=CC=C3)N	IC50 = 390000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B2C1UH	2-Amino-3-methyl-pentanoic acid cyclopentylamide	Investigative	24703639	C11H22N2O	198.31	CCC(C)C(C(=O)NC1CCCC1)N	IC50 = 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B2DY5F	(6S)-1-[(2S)-2-Amino-4-[2-(2-methoxyethyl)-4-(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoro-6-hydroxypiperidin-2-one	Investigative	44126292	C20H26F5N5O4	495.4	COCCC1=NC2=C(CCN(C2)C(=O)C[C@@H](CN3[C@H](C(CCC3=O)(F)F)O)N)C(=N1)C(F)(F)F	IC50 > 400000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B2H4MR	(S)-3-Amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid	Investigative	11206225	C8H14N2O3	186.21	C1CCN(C1)C(=O)[C@H](CC(=O)O)N	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B3FTC1	Diphenyl 1-((2S,3S)-2-amino-3-methylpentanoyl)pyrrolidin-2-ylphosphonate	Investigative	10341846	C22H29N2O4P	416.4	CC[C@H](C)[C@@H](C(=O)N1CCCC1P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3)N	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B3REA8	2-Amino-1-azepan-1-yl-3-methyl-pentan-1-one	Investigative	24704198	C12H24N2O	212.33	CCC(C)C(C(=O)N1CCCCCC1)N	IC50 = 228000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B67IAM	Fluoro-Olefin Analogue 9	Investigative	23646088	C14H24FN	225.35	C1CCC(CC1)NCC(=C2CCCCC2)F	IC50 = 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B6F0CW	Benzyl N-[(2S)-6-amino-1-[1-bis(4-acetamidophenoxy)phosphoryl-1,3-dihydroisoindol-2-yl]-1-oxohexan-2-yl]carbamate	Investigative	44435316	C38H42N5O8P	727.7	CC(=O)NC1=CC=C(C=C1)OP(=O)(C2C3=CC=CC=C3CN2C(=O)[C@H](CCCCN)NC(=O)OCC4=CC=CC=C4)OC5=CC=C(C=C5)NC(=O)C	IC50 > 250000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B6R1JK	2-Amino-1-(2,5-dihydro-pyrrol-1-yl)-3-methyl-pentan-1-one	Investigative	44364338	C10H18N2O	182.26	CCC(C)C(C(=O)N1CC=CC1)N	IC50 = 288000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B6YX3Z	N-[[(2S,3As,7aS)-1-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-2-yl]methyl]-1,1,1-trifluoromethanesulfonamide	Investigative	101879512	C20H25F6N3O3S	501.5	C1CC[C@H]2[C@@H](C1)C[C@H](N2C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CNS(=O)(=O)C(F)(F)F	IC50 = 207350 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B8JN1W	2-Amino-1-(3-hydroxy-pyrrolidin-1-yl)-3-methyl-pentan-1-one	Investigative	44364210	C10H20N2O2	200.28	CCC(C)C(C(=O)N1CCC(C1)O)N	IC50 = 299000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	B95RMJ	2-Amino-3-methyl-pentanoic acid diethylamide	Investigative	17763521	C10H22N2O	186.29	CCC(C)C(C(=O)N(CC)CC)N	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BCA7J5	(2S,3R)-2-Amino-3-hydroxy-1-(pyrrolidin-1-yl)butan-1-one	Investigative	44560823	C8H16N2O2	172.22	C[C@H]([C@@H](C(=O)N1CCCC1)N)O	IC50 = 230000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BF41BR	1-Isoleucylazetidine	Investigative	10607253	C9H18N2O	170.25	CC[C@H](C)[C@@H](C(=O)N1CCC1)N	IC50 = 730000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BHDS65	2-Amino-3-methyl-pentanoic acid methyl-propyl-amide	Investigative	43271345	C10H22N2O	186.29	CCCN(C)C(=O)C(C(C)CC)N	IC50 = 213000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BHEK84	(2S,3S)-2-Amino-1-(3-hydroxypyrrolidin-1-yl)-3-methylpentan-1-one	Investigative	10845727	C10H20N2O2	200.28	CC[C@H](C)[C@@H](C(=O)N1CCC(C1)O)N	IC50 = 299000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BI6AY3	Ethanone, 2-(cyclohexylamino)-1-(1-pyrrolidinyl)-	Investigative	11229581	C12H22N2O	210.32	C1CCC(CC1)NCC(=O)N2CCCC2	IC50 = 276000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BJAF95	Diphenyl 2-((2S,3S)-2-amino-3-methylpentanoyl)isoindolin-1-ylphosphonate	Investigative	23657402	C26H29N2O4P	464.5	CC[C@H](C)[C@@H](C(=O)N1CC2=CC=CC=C2C1P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4)N	IC50 > 250000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BL54HE	2-(Benzylamino)-1-(pyrrolidin-1-yl)ethan-1-one	Investigative	11356421	C13H18N2O	218.29	C1CCN(C1)C(=O)CNCC2=CC=CC=C2	IC50 = 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BL67JA	Pyrrolidin-1-yl-(tetrahydro-thiophen-2-yl)-methanone	Investigative	44364227	C9H15NOS	185.29	C1CCN(C1)C(=O)C2CCCS2	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BM4BI3	Pyrrolidin-2-yl-pyrrolidin-1-yl-methanethione	Investigative	44328319	C9H16N2S	184.3	C1CCN(C1)C(=S)C2CCCN2	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BM5FI2	1-Isoleucylhexahydro-1H-azepine	Investigative	10798619	C12H24N2O	212.33	CC[C@H](C)[C@@H](C(=O)N1CCCCCC1)N	IC50 = 228000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BQ5EM6	Piperidine, 1-[[(phenylmethyl)amino]acetyl]-	Investigative	11776124	C14H20N2O	232.32	C1CCN(CC1)C(=O)CNCC2=CC=CC=C2	IC50 = 397000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BSK8E6	2-Amino-1-azetidin-1-yl-3-methyl-pentan-1-one	Investigative	9964212	C9H18N2O	170.25	CCC(C)C(C(=O)N1CCC1)N	IC50 = 730000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BU5N4E	Benzyl (S)-6-amino-1-(2-(diphenoxyphosphoryl)pyrrolidin-1-yl)-1-oxohexan-2-ylcarbamate	Investigative	10393133	C30H36N3O6P	565.6	C1CC(N(C1)C(=O)[C@H](CCCCN)NC(=O)OCC2=CC=CC=C2)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BX4IY0	2-(Benzylamino)-1-cyclopentylethanethione	Investigative	44387756	C14H19NS	233.37	C1CCC(C1)C(=S)CNCC2=CC=CC=C2	IC50 > 250000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BXMR21	1-Isoleucyl-3-pyrroline	Investigative	10845163	C10H18N2O	182.26	CC[C@H](C)[C@@H](C(=O)N1CC=CC1)N	IC50 = 288000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BXMS65	2-Amino-3-methyl-pentanoic acid ethyl-methyl-amide	Investigative	23595882	C9H20N2O	172.27	CCC(C)C(C(=O)N(C)CC)N	IC50 > 500000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BYKP05	(2S)-1-[(2S)-2-Amino-3-(2-fluorophenyl)propanoyl]pyrrolidine-2-carbonitrile	Investigative	72697059	C14H16FN3O	261.29	C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=CC=C2F)N)C#N	IC50 = 296900 nM	Non binder
T50773	Dipeptidyl-peptidase 7	BZ16NK	Diphenyl 2-((2S,3R)-2-amino-3-methylpentanoyl)isoindolin-1-ylphosphonate	Investigative	23655474	C26H29N2O4P	464.5	CC[C@@H](C)[C@@H](C(=O)N1CC2=CC=CC=C2C1P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4)N	IC50 > 250000 nM	Non binder
T50773	Dipeptidyl-peptidase 7	D07IJU	(S)-pyrrolidin-1-yl(pyrrolidin-2-yl)methanone	Investigative	13578534	C9H16N2O	168.24	C1CCN(C1)C(=O)[C@@H]2CCCN2	IC50 > 500000 nM	Non binder