TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T50688 Glycoprotein IIb/IIIa receptor D09ZXO Cilengitide Phase 3 176873 C27H40N8O7 588.7 CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N IC50 = 206000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B01FCM Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-2-oxopiperidine-4-carboxylate;2,2,2-trifluoroacetic acid Investigative 73350496 C24H26F3N5O8S 601.6 CCOC(=O)C1CCN(C(=O)C1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B01RGZ 2-[1-[(2S)-2-[[4-(Diaminomethylideneamino)benzoyl]amino]propanoyl]piperidin-4-yl]acetic acid Investigative 44306547 C18H25N5O4 375.4 C[C@@H](C(=O)N1CCC(CC1)CC(=O)O)NC(=O)C2=CC=C(C=C2)N=C(N)N IC50 = 741310.24 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B03FSW (2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]acetyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]-5-amino-5-oxopentanoyl]amino]propanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoic acid Investigative 15088300 C52H82N18O17 1231.3 C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@H](CC2=CN=CN2)NC(=O)C IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B0CJD2 16-Acetylamino-7-carbamoylmethyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadecane-4-carboxylic acid amide Investigative 73346997 C23H40N10O7S2 632.8 CC(=O)N[C@@H]1CSSC([C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@H](N(C1=O)C)CCCN=C(N)N)CC(=O)N)C(=O)N)(C)C IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B0I5LD (3S)-3-[[2-[[(2S)-2-Acetamido-5-(carbamoylamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088303 C17H29N7O9 475.5 CC(=O)N[C@@H](CCCNC(=O)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B14HJM Klerval Investigative 44462165 C26H45N5O6 523.7 CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](CC1CCCCC1)C(=O)N)C(=O)CCCC2CCNCC2 IC50 > 2350000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B1ERF7 (3S)-3-[[(2S)-1-[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088306 C20H34N8O8 514.5 CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B1GW7D ((S)-1-{2-[(4-Guanidinomethyl-cyclohexanecarbonyl)-amino]-acetyl}-3-oxo-4-phenethyl-piperazin-2-yl)-acetic acid Investigative 10553451 C25H36N6O5 500.6 C1CC(CCC1CN=C(N)N)C(=O)NCC(=O)N2CCN(C(=O)[C@@H]2CC(=O)O)CCC3=CC=CC=C3 IC50 > 1000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B1RQ0U 3-{[3-Oxo-2-(2-piperidin-4-yl-ethyl)-indane-5-carbonyl]-amino}-propionic acid Investigative 22402471 C20H26N2O4 358.4 C1CNCCC1CCC2CC3=C(C2=O)C=C(C=C3)C(=O)NCCC(=O)O IC50 = 2300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B1Z2BP (S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[ethyl-(4-piperidin-4-yl-butyryl)-amino]-acetylamino}-succinamic acid Investigative 9984308 C26H44N4O7 524.6 CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1CCCCC1)C(=O)O)C(=O)CCCC2CCNCC2 IC50 = 1012000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B24EBN Ethyl 2-[benzyl-[(2S)-2-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid Investigative 71654376 C29H28F3N3O8 603.5 CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)O[C@H](CO3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B28ELR Ethyl 1-[4-[(5S)-5-[[(3-amino-4-chlorobenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate Investigative 71699203 C25H29ClN4O5 501 CCOC(=O)C1CCN(CC1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CC(=C(C=C4)Cl)N IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B2BWK6 3-{[6-(2-Piperidin-4-yl-ethylcarbamoyl)-pyridine-2-carbonyl]-amino}-propionic acid Investigative 44297845 C17H24N4O4 348.4 C1CNCCC1CCNC(=O)C2=NC(=CC=C2)C(=O)NCCC(=O)O IC50 = 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B39PJM (S)-N-((R)-1-Carboxy-3-cyclohexyl-propyl)-3-{2-[ethyl-(4-piperidin-4-yl-butyryl)-amino]-acetylamino}-succinamic acid Investigative 44462164 C27H46N4O7 538.7 CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](CCC1CCCCC1)C(=O)O)C(=O)CCCC2CCNCC2 IC50 = 1930000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B3B9ON (3S)-3-[[2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1-(ethylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088316 C19H34N8O8 502.5 CCNC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)C IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B3XK5O [16-Acetylamino-4-carbamoyl-13-(4-guanidino-butyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid Investigative 73350084 C23H39N9O8S2 633.7 CC(=O)N[C@@H]1CSSC([C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@H](NC1=O)CCCCN=C(N)N)CC(=O)O)C(=O)N)(C)C IC50 = 385000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B45NTB Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-3-methyl-2-oxopiperidine-3-carboxylate;2,2,2-trifluoroacetic acid Investigative 73356536 C25H28F3N5O8S 615.6 CCOC(=O)C1(CCCN(C1=O)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N)C.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B4A8PD (3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 44336250 C18H32N8O8 488.5 C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B4RNU5 4-(2-Bromoacetamido)-TEMPO Investigative 16211712 C11H20BrN2O2 292.19 CC1(CC(CC(N1[O])(C)C)NC(=O)CBr)C Ki > 1000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B4THC3 1-[(S)-2-[4-(Guanidinomethyl)benzoylamino]propionyl]piperidine-4-carboxylic acid Investigative 44306543 C18H25N5O4 375.4 C[C@@H](C(=O)N1CCC(CC1)C(=O)O)NC(=O)C2=CC=C(C=C2)CN=C(N)N IC50 = 707945.78 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B5Q7BV Ethyl 2-[benzyl-[(2R)-2-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid Investigative 71654374 C29H28F3N3O8 603.5 CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)O[C@@H](CO3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B7AQX6 (2R)-2-[[2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 44336210 C17H30N8O8 474.5 CC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@H](CC(=O)N[C@@H](CO)C(=O)N)C(=O)O IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B7HGD4 [(4S,7S,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid Investigative 15088322 C22H37N9O8S2 619.7 CC(=O)N[C@@H]1CSSC([C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](NC1=O)CCCN=C(N)N)CC(=O)O)C(=O)N)(C)C IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B7PGR6 Ethyl 2-[benzyl-[(3R)-3-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid Investigative 71654530 C29H28F3N3O8 603.5 CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)OC[C@H](O3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B85FRU (2S)-2-[[2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]butanedioic acid Investigative 90645591 C21H31N7O7 493.5 C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O)N IC50 = 947000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B8A5KJ (4S)-4-[[2-[[(2S)-2-Acetamido-6-aminohexanoyl]amino]acetyl]amino]-5-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid Investigative 15088312 C18H32N6O8 460.5 CC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B9FN4U (2S)-2-[[2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]butanediamide Investigative 15088308 C17H31N9O7 473.5 CC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor B9P5MB 1-[4-[(5S)-5-[[(5-Chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid Investigative 73348933 C21H22ClN3O5S 463.9 C1CN(CCC1C(=O)O)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BAX9K5 Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate;2,2,2-trifluoroacetic acid Investigative 73356532 C24H28F3N5O7S 587.6 CCOC(=O)C1CCN(CC1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BBA43I 3-{3-[(Piperidin-4-ylmethyl)-carbamoyl]-benzoylamino}-propionic acid Investigative 19034178 C17H23N3O4 333.4 C1CNCCC1CNC(=O)C2=CC=CC(=C2)C(=O)NCCC(=O)O IC50 = 330000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BC4J3T (3S)-3-[[2-[[(2S)-2-Acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088304 C17H25N7O8 455.4 CC(=O)N[C@@H](CC1=CN=CN1)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BD8W9J 2-Benzyloxycarbonylamino-3-[4-(3-phenyl-propoxy)-phenyl]-propionic acid Investigative 10252306 C26H27NO5 433.5 C1=CC=C(C=C1)CCCOC2=CC=C(C=C2)C[C@@H](C(=O)O)NC(=O)OCC3=CC=CC=C3 IC50 > 1000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BF58YL Cyclo(Arg-Gly-Asp-D-Pro-Pro-Gly) Investigative 15931147 C24H37N9O8 579.6 C1C[C@H]2C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3CCC[C@@H]3C(=O)N2C1)CC(=O)O)CCCN=C(N)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BF5J6Z (S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid Investigative 9870468 C22H22Cl2N2O5S 497.4 CC(=O)N1CSC[C@@H]1C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=C(C=CC=C3Cl)Cl)C(=O)O IC50 > 400000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BFQ12Y Ethyl 1-[4-[(5R)-5-[[(3-amino-4-chlorobenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate Investigative 71699286 C25H29ClN4O5 501 CCOC(=O)C1CCN(CC1)C2=CC=C(C=C2)N3C[C@H](OC3=O)CNC(=O)C4=CC(=C(C=C4)Cl)N IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BHO2W5 (3S)-3-[[2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]-methylamino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088307 C18H32N8O8 488.5 CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N(C)CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BIN80F 2-(2-{2-[2-(2-Amino-acetylamino)-5-guanidino-pentanoylamino]-acetylamino}-3-carboxy-propionylamino)-succinic acid Investigative 44304954 C18H30N8O10 518.5 C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)CN)CN=C(N)N IC50 > 500000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BJ2RX6 (3S)-3-[[2-[[(2R)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088298 C17H30N8O8 474.5 CC(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BJF45Y 2-[5-[2-[[4-(1H-Benzimidazol-2-ylamino)cyclohexyl]methylamino]-2-oxoethyl]-6-oxo-11H-benzo[c][1]benzazepin-11-yl]acetic acid Investigative 11757316 C32H33N5O4 551.6 C1CC(CCC1CNC(=O)CN2C3=CC=CC=C3C(C4=CC=CC=C4C2=O)CC(=O)O)NC5=NC6=CC=CC=C6N5 IC50 = 1000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BJT93B Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-3-carboxylate;2,2,2-trifluoroacetic acid Investigative 73348935 C24H28F3N5O7S 587.6 CCOC(=O)C1CCCN(C1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BK0LQ7 2-[5-[2-[[4-(1H-Benzimidazol-2-ylamino)phenyl]methylamino]-2-oxoethyl]-6-oxo-11H-benzo[c][1]benzazepin-11-yl]acetic acid Investigative 10325138 C32H27N5O4 545.6 C1=CC=C2C(=C1)C(C3=CC=CC=C3N(C2=O)CC(=O)NCC4=CC=C(C=C4)NC5=NC6=CC=CC=C6N5)CC(=O)O IC50 = 1000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BKIL31 (3R)-3-[[2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 71452640 C17H30N8O8 474.5 CC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BKOZ83 Ethyl 2-[benzyl-[(3S)-3-[(4-carbamimidoylphenoxy)methyl]-2,3-dihydro-1,4-benzodioxin-6-yl]amino]-2-oxoacetate;2,2,2-trifluoroacetic acid Investigative 71654532 C29H28F3N3O8 603.5 CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)OC[C@@H](O3)COC4=CC=C(C=C4)C(=N)N.C(=O)(C(F)(F)F)O IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BKPT81 1-[Methyl(4-guanidinobenzoyl)aminoacetyl]piperidine-4-acetic acid Investigative 44306616 C18H25N5O4 375.4 CN(CC(=O)N1CCC(CC1)CC(=O)O)C(=O)C2=CC=C(C=C2)N=C(N)N IC50 = 758577.58 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BL2SN3 3-{[1-Oxo-9-phenyl-2-(2-piperidin-4-yl-ethyl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepine-8-carbonyl]-amino}-propionic acid Investigative 44362951 C25H32N4O4 452.5 C1CN2C=C(C(=C2C(=O)N(C1)CCC3CCNCC3)C4=CC=CC=C4)C(=O)NCCC(=O)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BM4GP8 Ethyl 1-[4-[(5R)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate;2,2,2-trifluoroacetic acid Investigative 73347404 C24H28F3N5O7S 587.6 CCOC(=O)C1CCN(CC1)C2=CC=C(C=C2)N3C[C@H](OC3=O)CNC(=O)C4=CN=C(S4)N.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BN1SF0 1-[4-[(5S)-5-[[(2-Amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-3-carboxylic acid;2,2,2-trifluoroacetic acid Investigative 73353473 C22H24F3N5O7S 559.5 C1CC(CN(C1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N)C(=O)O.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BNO21R 3-(4-Piperazin-1-yl-benzoylamino)-propionic acid Investigative 44381942 C14H19N3O3 277.32 C1CN(CCN1)C2=CC=C(C=C2)C(=O)NCCC(=O)O IC50 = 230000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BO94MR Methyl 1-[2-[(4-carbamimidoylbenzoyl)-methylamino]acetyl]piperidine-4-carboxylate Investigative 44382481 C18H24N4O4 360.4 CN(CC(=O)N1CCC(CC1)C(=O)OC)C(=O)C2=CC=C(C=C2)C(=N)N IC50 = 331131.12 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BPHB48 3-[1-Oxo-6-(2-piperidin-4-yl-ethylcarbamoyl)-1,3-dihydro-isoindol-2-yl]-propionic acid Investigative 44297814 C19H25N3O4 359.4 C1CNCCC1CCNC(=O)C2=CC3=C(CN(C3=O)CCC(=O)O)C=C2 IC50 = 10000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BPX0N5 16-(2-Acetylamino-6-amino-hexanoylamino)-7-carboxymethyl-3,3,13-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadecane-4-carboxylic acid Investigative 73353038 C25H41N7O10S2 663.8 C[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SSC[C@@H](C(=O)N1)NC(=O)[C@H](CCCCN)NC(=O)C)(C)C)C(=O)O)CC(=O)O IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BPX43O 1-[4-[(5S)-5-[[(2-Amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-3-methyl-2-oxopiperidine-3-carboxylic acid;2,2,2-trifluoroacetic acid Investigative 73347406 C23H24F3N5O8S 587.5 CC1(CCCN(C1=O)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N)C(=O)O.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BQ9G1M (4S)-4-[[2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-5-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid Investigative 15088309 C18H32N8O8 488.5 CC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BS0HG7 Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-2-carboxylate;2,2,2-trifluoroacetic acid Investigative 73353474 C24H28F3N5O7S 587.6 CCOC(=O)C1CCCCN1C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CN=C(S4)N.C(=O)(C(F)(F)F)O IC50 > 300000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BSI42H 2-[(3S,6R,12R,15S,21S,24R,30R,33S)-3,21-Dibenzyl-24-(carboxymethyl)-12,30-bis[3-(diaminomethylideneamino)propyl]-2,5,8,11,14,20,23,26,29,32-decaoxo-1,4,7,10,13,19,22,25,28,31-decazatricyclo[31.3.0.015,19]hexatriacontan-6-yl]acetic acid Investigative 44351621 C52H72N16O14 1145.2 C1C[C@H]2C(=O)N[C@@H](C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N[C@@H](C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](C(=O)N2C1)CC4=CC=CC=C4)CC(=O)O)CCCN=C(N)N)CC5=CC=CC=C5)CC(=O)O)CCCN=C(N)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BV12IU 1-[3-(4-Guanidinobenzoylamino)propionyl]piperidine-4-carboxylic acid Investigative 44307296 C17H23N5O4 361.4 C1CN(CCC1C(=O)O)C(=O)CCNC(=O)C2=CC=C(C=C2)N=C(N)N IC50 = 758577.58 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BWD4J9 Arginyl-glycyl-aspartyl-phenylalanine Investigative 3080994 C21H31N7O7 493.5 C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)N IC50 = 725000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BWOU42 (3S)-3-[[2-[[(2S)-2-Acetamido-6-aminohexanoyl]amino]acetyl]amino]-4-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Investigative 15088302 C17H30N6O8 446.5 CC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N IC50 > 200000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BWSC75 3-{2-[2-(2-Acetylamino-acetylamino)-5-guanidino-pentanoylamino]-acetylamino}-N-(1-carbamoyl-2-methyl-propyl)-succinamic acid Investigative 44304495 C21H37N9O8 543.6 CC(C)[C@@H](C(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C IC50 > 500000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BWX8P9 (5S,8S)-3-[(S)-2-Carboxy-2-(2,4,6-trimethyl-benzenesulfonylamino)-ethylcarbamoyl]-8-(pyridin-2-ylaminomethyl)-1-oxa-2,7-diaza-spiro[4.4]non-2-ene-7-carboxylic acid benzyl ester Investigative 44350342 C33H38N6O8S 678.8 CC1=CC(=C(C(=C1)C)S(=O)(=O)N[C@@H](CNC(=O)C2=NO[C@]3(C2)C[C@H](N(C3)C(=O)OCC4=CC=CC=C4)CNC5=CC=CC=N5)C(=O)O)C IC50 > 1000000 nM Non binder T50688 Glycoprotein IIb/IIIa receptor BX52SA 1-[4-[(5R)-5-[[(5-Chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid Investigative 73347403 C21H22ClN3O5S 463.9 C1CN(CCC1C(=O)O)C2=CC=C(C=C2)N3C[C@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl IC50 > 300000 nM Non binder