TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T48940 HIF-prolyl hydroxylase B7LSF4 (5S,7R)-5-(3-Bromo-5-fluorophenyl)-7-(3-bromophenyl)-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine Investigative 136268869 C16H12Br2FN5 453.11 C1[C@H](NC2=NN=NN2[C@H]1C3=CC(=CC=C3)Br)C4=CC(=CC(=C4)Br)F IC50 = 14500000 nM Non binder T48940 HIF-prolyl hydroxylase BI82AL (5S,7R)-7-(3-Bromo-2,6-difluorophenyl)-5-(3-bromophenyl)-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine Investigative 136268880 C16H11Br2F2N5 471.1 C1[C@H](NC2=NN=NN2[C@H]1C3=C(C=CC(=C3F)Br)F)C4=CC(=CC=C4)Br IC50 = 3800000 nM Non binder T48940 HIF-prolyl hydroxylase BMEJ49 (5S,7R)-5-(3-Bromophenyl)-7-(2-bromophenyl)-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine Investigative 136268872 C16H13Br2N5 435.12 C1[C@H](NC2=NN=NN2[C@H]1C3=CC=CC=C3Br)C4=CC(=CC=C4)Br IC50 = 18900000 nM Non binder T48940 HIF-prolyl hydroxylase BVI5O4 (2R)-1-[3-[2-(3,4-Dimethoxyphenyl)-2-oxoethoxy]-4-methoxyphenyl]-2-[4-[(2S,3R,4R,5S)-5-[4-[(2R)-1-[3-[2-(3,4-dimethoxyphenyl)-2-oxoethoxy]-4-methoxyphenyl]-1-oxopropan-2-yl]oxy-3-methoxyphenyl]-3,4-dimethyloxolan-2-yl]-2-methoxyphenoxy]propan-1-one Investigative 122192795 C60H64O17 1057.1 C[C@@H]1[C@H]([C@H](O[C@@H]1C2=CC(=C(C=C2)O[C@H](C)C(=O)C3=CC(=C(C=C3)OC)OCC(=O)C4=CC(=C(C=C4)OC)OC)OC)C5=CC(=C(C=C5)O[C@H](C)C(=O)C6=CC(=C(C=C6)OC)OCC(=O)C7=CC(=C(C=C7)OC)OC)OC)C IC50 > 10000000 nM Non binder