TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T47768	Opioid receptor mu	B10IPH	(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-12-(2,2-dimethylpropyl)-4,10-dihydroxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107956	C25H35NO3	397.5	CC(C)(C)C[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	B2JT1F	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]acetamide	Investigative	77107354	C22H28N2O4	384.5	CC(=O)N[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	B3U7RK	(1R,9R,10S,12S)-12-Butyl-17-(cyclopropylmethyl)-4,10-dihydroxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107955	C24H33NO3	383.5	CCCC[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	B4CBH1	(1R,9R,10S,12S)-12-(Cyclohexylmethyl)-17-(cyclopropylmethyl)-4,10-dihydroxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77104974	C27H37NO3	423.6	C1CCC(CC1)C[C@H]2C[C@]3([C@H]4CC5=C([C@@]3(CCN4CC6CC6)CC2=O)C=C(C=C5)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	B4PCI6	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]ethanesulfonamide	Investigative	77107953	C22H30N2O5S	434.6	CCS(=O)(=O)N[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	B9KL3M	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]benzenesulfonamide	Investigative	77107952	C26H30N2O5S	482.6	C1CC1CN2CC[C@]34CC(=O)[C@H](C[C@]3([C@H]2CC5=C4C=C(C=C5)O)O)NS(=O)(=O)C6=CC=CC=C6	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	B9LN8F	(1R,9R,10S,12E)-17-(Cyclopropylmethyl)-10-hydroxy-4-methoxy-12-(3-methylbutylidene)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107759	C26H35NO3	409.6	CC(C)C/C=C/1\\C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)OC)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BA6U9M	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]cyclopentanecarboxamide	Investigative	77107557	C26H34N2O4	438.6	C1CCC(C1)C(=O)N[C@H]2C[C@]3([C@H]4CC5=C([C@@]3(CCN4CC6CC6)CC2=O)C=C(C=C5)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BE8Y7H	(2S)-1-[2-[(1R,9R,10S,12R)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]acetyl]pyrrolidine-2-carboxylic acid	Investigative	77106954	C27H34N2O6	482.6	C1C[C@H](N(C1)C(=O)C[C@H]2C[C@]3([C@H]4CC5=C([C@@]3(CCN4CC6CC6)CC2=O)C=C(C=C5)O)O)C(=O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BFP8U0	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]-2-methylpropanamide	Investigative	77107355	C24H32N2O4	412.5	CC(C)C(=O)N[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BHY02W	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]propanamide	Investigative	77107356	C23H30N2O4	398.5	CCC(=O)N[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BMF58V	2-[(1R,9R,10S)-12-(Carboxymethyl)-17-(cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]acetic acid	Investigative	77106553	C24H29NO7	443.5	C1CC1CN2CC[C@]34CC(=O)C(C[C@]3([C@H]2CC5=C4C=C(C=C5)O)O)(CC(=O)O)CC(=O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BPFZ34	(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-12-(2-methylpropyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107957	C24H33NO3	383.5	CC(C)C[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BR39QY	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]cyclopropanecarboxamide	Investigative	77107556	C24H30N2O4	410.5	C1CC1CN2CC[C@]34CC(=O)[C@H](C[C@]3([C@H]2CC5=C4C=C(C=C5)O)O)NC(=O)C6CC6	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BR8O1V	(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-12-(2-methylbutyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107758	C25H35NO3	397.5	CCC(C)C[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BRI8V2	2-[(1R,9R,10S,12R)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]acetic acid	Investigative	77106554	C22H27NO5	385.5	C1CC1CN2CC[C@]34CC(=O)[C@H](C[C@]3([C@H]2CC5=C4C=C(C=C5)O)O)CC(=O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BTAF53	(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-12-(3-methylbutyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107756	C25H35NO3	397.5	CC(C)CC[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BU5S2W	(S)-(1,2,3,5,6,8a-Hexahydroindolizin-8-yl)(2-methoxy-6-methylphenyl)methanone	Investigative	46880271	C17H21NO2	271.35	CC1=C(C(=CC=C1)OC)C(=O)C2=CCCN3[C@H]2CCC3	Ki > 200000 nM	Non binder
T47768	Opioid receptor mu	BV0KH3	(1R,9R,10S,12S)-12-(Cyclopentylmethyl)-17-(cyclopropylmethyl)-4,10-dihydroxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one	Investigative	77107757	C26H35NO3	409.6	C1CCC(C1)C[C@H]2C[C@]3([C@H]4CC5=C([C@@]3(CCN4CC6CC6)CC2=O)C=C(C=C5)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BYP6M7	(2S)-N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]-2-methylbutanamide	Investigative	77107755	C25H34N2O4	426.5	CC[C@H](C)C(=O)N[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder
T47768	Opioid receptor mu	BZL79Y	N-[(1R,9R,10S,12S)-17-(Cyclopropylmethyl)-4,10-dihydroxy-13-oxo-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-12-yl]-3-methylbutanamide	Investigative	77107555	C25H34N2O4	426.5	CC(C)CC(=O)N[C@H]1C[C@]2([C@H]3CC4=C([C@@]2(CCN3CC5CC5)CC1=O)C=C(C=C4)O)O	EC50 > 200000 nM	Non binder