TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T42881	Cytomegalovirus Protease	B0VU4Y	(3As,6S,6aR)-6-Methyl-4-methylcarbamoyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	493458	C17H21N3O4	331.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)NC	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	B1EGN4	4-(4-Methoxy-benzoyl)-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44296322	C23H24N2O5	408.4	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C4=CC=C(C=C4)OC	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	B2KU4L	Benzyl (3aS,6S,6aR)-4-dimethoxyphosphoryl-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	490599	C17H23N2O6P	382.3	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)P(=O)(OC)OC	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	B2R1KP	4-Formyl-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44296321	C16H18N2O4	302.32	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C=O	IC50 = 398000 nM	Non binder
T42881	Cytomegalovirus Protease	B3I9XY	(3As,6S,6aR)-6-Methyl-5-oxo-4-thiazol-2-yl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	493461	C18H19N3O3S	357.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C4=NC=CS4	IC50 ~ 500000 nM	Non binder
T42881	Cytomegalovirus Protease	B3RV7G	4-Acetyl-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44295724	C17H20N2O4	316.35	C[C@@H]1C2[C@@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C	IC50 > 1000000 nM	Non binder
T42881	Cytomegalovirus Protease	B75FSQ	Benzyl (3aS,6S,6aR)-6-methyl-4-methylsulfonyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	6481314	C16H20N2O5S	352.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)S(=O)(=O)C	IC50 ~ 500000 nM	Non binder
T42881	Cytomegalovirus Protease	B8B5FL	Benzyl (3aS,6S,6aR)-6-methyl-4-(4-nitrophenyl)-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	493460	C21H21N3O5	395.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C4=CC=C(C=C4)[N+](=O)[O-]	IC50 ~ 500000 nM	Non binder
T42881	Cytomegalovirus Protease	B9Q3MZ	(3As,6S,6aR)-4-Benzylcarbamoyl-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	493459	C23H25N3O4	407.5	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)NCC4=CC=CC=C4	IC50 = 250000 nM	Non binder
T42881	Cytomegalovirus Protease	BBD07E	4-(2,2-Dimethyl-propionyl)-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44295910	C20H26N2O4	358.4	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C(C)(C)C	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BBR76H	Benzyl (3aS,6aR)-4-acetyl-6,6-dimethyl-5-oxo-2,3,3a,6a-tetrahydropyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	493455	C18H22N2O4	330.4	CC(=O)N1[C@H]2CCN([C@@H]2C(C1=O)(C)C)C(=O)OCC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BFG5S8	Benzyl (3aS,6S,6aR)-6-methyl-5-oxo-4-(2,2,3,3-tetramethylcyclopropanecarbonyl)-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	490592	C23H30N2O4	398.5	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C4C(C4(C)C)(C)C	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BL0RY6	6-Methyl-5-oxo-4-(2,2,3,3-tetramethyl-cyclopropanecarbonyl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44296323	C23H30N2O4	398.5	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C4C(C4(C)C)(C)C	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BQ3U0P	Benzyl (3aS,6S,6aR)-4-(2,2-dimethylpropanoyl)-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	490585	C20H26N2O4	358.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C(C)(C)C	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BSF9A1	{(S)-2,2-Dimethyl-1-[(S)-3-methyl-1-(4-oxo-azetidin-2-yloxymethyl)-butylcarbamoyl]-propyl}-carbamic acid tert-butyl ester	Investigative	456164	C20H37N3O5	399.5	CC(C)C[C@@H](COC1CC(=O)N1)NC(=O)[C@H](C(C)(C)C)NC(=O)OC(C)(C)C	IC50 > 300000 nM	Non binder
T42881	Cytomegalovirus Protease	BU1P5Z	4-(2-Hydroxy-3-phenoxy-propyl)-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44295551	C24H28N2O5	424.5	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)CC(COC4=CC=CC=C4)O	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BVD94N	(3Ar,6R,6aS)-4-acetyl-1-[(2S)-1-benzoylpyrrolidine-2-carbonyl]-6-methyl-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrol-5-one	Investigative	11025393	C21H25N3O4	383.4	C[C@@H]1[C@H]2[C@@H](CCN2C(=O)[C@@H]3CCCN3C(=O)C4=CC=CC=C4)N(C1=O)C(=O)C	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BWIF06	(3Ar,6R,6aS)-4-acetyl-1-[(2S)-1-[5-(dimethylamino)naphthalen-1-yl]sulfonylpyrrolidine-2-carbonyl]-6-methyl-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrol-5-one	Investigative	10874917	C26H32N4O5S	512.6	C[C@@H]1[C@H]2[C@@H](CCN2C(=O)[C@@H]3CCCN3S(=O)(=O)C4=CC=CC5=C4C=CC=C5N(C)C)N(C1=O)C(=O)C	IC50 > 500000 nM	Non binder
T42881	Cytomegalovirus Protease	BY1B2P	Benzyl (3aS,6S,6aR)-4-(2,4-dinitrophenyl)-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	490601	C21H20N4O7	440.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C4=C(C=C(C=C4)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 500000 nM	Non binder