TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T41141	Cathepsin L	B1KJN5	(1r)-1-{[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]methyl}-2,2-dimethylpropyl(1S)-1-[oxo(1h-pyrazol-5-ylamino)acetyl]pentylcarbamate	Investigative	10186046	C25H31FN6O5	514.5	CCCC[C@@H](C(=O)C(=O)NC1=CC=NN1)NC(=O)O[C@H](CC2=NN=C(O2)C3=CC=C(C=C3)F)C(C)(C)C	IC50 = 3800000 nM	Non binder
T41141	Cathepsin L	B29LUZ	[(2S)-3,3-Dimethyl-1-[3-[4-(trifluoromethyl)phenyl]pyrazol-1-yl]butan-2-yl] N-[(3S)-1-(1,2-oxazol-5-ylmethylamino)-1,2-dioxoheptan-3-yl]carbamate	Investigative	10120903	C28H34F3N5O5	577.6	CCCC[C@@H](C(=O)C(=O)NCC1=CC=NO1)NC(=O)O[C@H](CN2C=CC(=N2)C3=CC=C(C=C3)C(F)(F)F)C(C)(C)C	IC50 = 1000000 nM	Non binder
T41141	Cathepsin L	B41XJK	(3S)-3-[[(2S)-1-Acetylpyrrolidine-2-carbonyl]amino]-5-(2,6-dimethylbenzoyl)oxy-4-oxopentanoic acid	Investigative	127053772	C21H26N2O7	418.4	CC1=C(C(=CC=C1)C)C(=O)OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)C	IC50 > 1000000 nM	Non binder
T41141	Cathepsin L	B52GPF	Chembl4244085	Investigative	145985030	C31H37N3O6	547.6	CCOC(=O)/C=C/C=C/C(=O)[C@H](CCC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)N3CCOCC3	Ki = 780000 nM	Non binder
T41141	Cathepsin L	B5B6JX	[(S)-1-(Thiazol-2-ylaminooxalyl)-pentyl]-carbamic acid (S)-2,2-dimethyl-1-[4-(4-trifluoromethyl-phenyl)-imidazol-1-ylmethyl]-propyl ester	Investigative	10303657	C27H32F3N5O4S	579.6	CCCC[C@@H](C(=O)C(=O)NC1=NC=CS1)NC(=O)O[C@H](CN2C=C(N=C2)C3=CC=C(C=C3)C(F)(F)F)C(C)(C)C	IC50 = 1000000 nM	Non binder
T41141	Cathepsin L	B5J9FW	2-(2-{2-Cyclohexyl-2-[(pyrazine-2-carbonyl)-amino]-acetylamino}-3,3-dimethyl-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid (1-cyclopropylaminooxalyl-3,3-difluoro-propyl)-amide	Investigative	3011892	C35H49F2N7O6	701.8	CC(C)(C)[C@@H](C(=O)N1CC2CCCC2[C@H]1C(=O)NC(CC(F)F)C(=O)C(=O)NC3CC3)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5	Ki = 760000 nM	Non binder
T41141	Cathepsin L	B8SVT0	Chembl4128058	Investigative	145963229	C17H23FN4O2	334.4	CN(C)CCCC[C@@H](C(=O)NCC#N)NC(=O)C1=CC=C(C=C1)F	IC50 = 816000 nM	Non binder
T41141	Cathepsin L	BGY1E9	[(S)-1-(Pyridin-2-ylaminooxalyl)-pentyl]-carbamic acid (S)-2,2-dimethyl-1-[3-(4-trifluoromethyl-phenyl)-pyrazol-1-ylmethyl]-propyl ester	Investigative	10303526	C29H34F3N5O4	573.6	CCCC[C@@H](C(=O)C(=O)NC1=CC=CC=N1)NC(=O)O[C@H](CN2C=CC(=N2)C3=CC=C(C=C3)C(F)(F)F)C(C)(C)C	IC50 = 240000 nM	Non binder
T41141	Cathepsin L	BMN95C	Ethyl (2R,3R)-3-[[(1-acetylpyrrolidine-2-carbonyl)amino]-(2-amino-2-oxoethyl)carbamoyl]oxirane-2-carboxylate	Investigative	127053771	C15H22N4O7	370.36	CCOC(=O)[C@H]1[C@@H](O1)C(=O)N(CC(=O)N)NC(=O)C2CCCN2C(=O)C	IC50 = 220000 nM	Non binder
T41141	Cathepsin L	BPUB08	Pyrrolidine, 1-(4-nitro-1-naphthalenyl)-	Investigative	4430623	C14H14N2O2	242.27	C1CCN(C1)C2=CC=C(C3=CC=CC=C32)[N+](=O)[O-]	Ki = 245000 nM	Non binder
T41141	Cathepsin L	BXT93U	Ridaura	Investigative	70788951	C20H35AuO9PS	679.5	CC[PH+](CC)CC.CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au]	IC50 > 250000 nM	Non binder
T41141	Cathepsin L	BZ24RN	(1R,21S,24S)-21-Tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,7.06,11]heptacosa-6(11),7,9-triene-24-carboxamide	Investigative	46228924	C38H53N5O9S	755.9	CC1(CCCCC2=C3CN(CC3=CC=C2)C(=O)O[C@@H]4C[C@H](N(C4)C(=O)[C@@H](NC(=O)OC1)C(C)(C)C)C(=O)N[C@@]5(C[C@H]5C=C)C(=O)NS(=O)(=O)C6CC6)C	IC50 > 10000000 nM	Non binder