TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T39996 Euchromatic histone-lysine N-methyltransferase 1 B0O9LD 5'-[(R)-1-Amino-2-cyclopropylethyl]-5'-deoxyadenosine Investigative 132609264 C15H22N6O3 334.37 C1CC1C[C@H](C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)N IC50 = 794300 nM Non binder T39996 Euchromatic histone-lysine N-methyltransferase 1 B5U4IT (2R,3S,4R,5R)-2-[(2S)-2-Amino-3-cyclohexylpropyl]-5-(6-aminopurin-9-yl)oxolane-3,4-diol Investigative 137632046 C18H28N6O3 376.5 C1CCC(CC1)C[C@@H](C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)N IC50 = 203700 nM Non binder T39996 Euchromatic histone-lysine N-methyltransferase 1 B7QFB9 N-[2-[(2-Amino-6-methylpyrimidin-4-yl)amino]phenyl]-4-(quinolin-4-ylamino)benzamide Investigative 76321898 C27H23N7O 461.5 CC1=CC(=NC(=N1)N)NC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54 IC50 = 400000 nM Non binder T39996 Euchromatic histone-lysine N-methyltransferase 1 BK51PI (2R,3R,4S,5R)-2-(6-Aminopurin-9-yl)-5-(3-phenylpropyl)oxolane-3,4-diol Investigative 90655765 C18H21N5O3 355.4 C1=CC=C(C=C1)CCC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O IC50 = 235000 nM Non binder T39996 Euchromatic histone-lysine N-methyltransferase 1 BOP6Y7 N-[3-[(2-Amino-6-methylpyrimidin-4-yl)amino]phenyl]-4-(quinolin-4-ylamino)benzamide Investigative 59457983 C27H23N7O 461.5 CC1=CC(=NC(=N1)N)NC2=CC(=CC=C2)NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54 IC50 = 600000 nM Non binder T39996 Euchromatic histone-lysine N-methyltransferase 1 BVP7X1 N-[2-[(2-Amino-6-methylpyrimidin-4-yl)amino]phenyl]-3-(quinolin-4-ylamino)benzamide Investigative 76314627 C27H23N7O 461.5 CC1=CC(=NC(=N1)N)NC2=CC=CC=C2NC(=O)C3=CC(=CC=C3)NC4=CC=NC5=CC=CC=C54 IC50 = 500000 nM Non binder T39996 Euchromatic histone-lysine N-methyltransferase 1 D00FLT Sinefungin Investigative 65482 C15H23N7O5 381.39 C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O)N IC50 = 513000 nM Non binder