TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T38763 Hepatitis C virus Non-structural 5B B30BQV 2-(Pyridin-2-yl)-1H-benzo[d]imidazole-6-carboxylic acid Investigative 513895 C13H9N3O2 239.23 C1=CC=NC(=C1)C2=NC3=C(N2)C=C(C=C3)C(=O)O IC50 > 500000 nM Non binder T38763 Hepatitis C virus Non-structural 5B B4ALR2 [[2-[(2R,3R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethyl-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-trihydroxyphosphanium Investigative 46905540 C12H21N5O12P3+ 520.24 C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CCP(=O)(O)OP(=O)(O)O[P+](O)(O)O)O)O Ki = 327000 nM Non binder T38763 Hepatitis C virus Non-structural 5B B5TS4W 1-Isopropyl-2-(2-pyridyl)benzimidazole-5-carboxylic acid Investigative 513899 C16H15N3O2 281.31 CC(C)N1C2=C(C=C(C=C2)C(=O)O)N=C1C3=CC=CC=N3 IC50 = 408000 nM Non binder T38763 Hepatitis C virus Non-structural 5B BJ9F7Z [[[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-trihydroxyphosphanium Investigative 46905539 C10H17N5O12P3+ 492.19 C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CP(=O)(O)OP(=O)(O)O[P+](O)(O)O)O)O)N Ki = 201000 nM Non binder T38763 Hepatitis C virus Non-structural 5B BQEG43 1-Phenyl-2-(2-pyridyl)benzimidazole-5-carboxylic acid Investigative 513902 C19H13N3O2 315.3 C1=CC=C(C=C1)N2C3=C(C=C(C=C3)C(=O)O)N=C2C4=CC=CC=N4 IC50 = 360000 nM Non binder T38763 Hepatitis C virus Non-structural 5B BRU7J5 [[[(1S,2S,3S,4R)-4-(6-Aminopurin-9-yl)-2,3-dihydroxycyclopentyl]oxymethyl-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-trihydroxyphosphanium Investigative 46905538 C11H19N5O12P3+ 506.22 C1[C@H]([C@@H]([C@@H]([C@H]1OCP(=O)(O)OP(=O)(O)O[P+](O)(O)O)O)O)N2C=NC3=C(N=CN=C32)N Ki = 229000 nM Non binder