TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T35565	Alkaline phosphatase	D00YPW	ZAPRINAST	Terminated	135399235	C13H13N5O2	271.27	.	IC50 = 6250000 nM	Non binder
T35565	Alkaline phosphatase	B1T6JO	Propylphosphonic acid	Investigative	204484	C3H9O3P	124.08	CCCP(=O)(O)O	Ki = 1550000 nM	Non binder
T35565	Alkaline phosphatase	B3QG6P	Phenylsulfanylmethyl-phosphonothioic acid	Investigative	11031366	C7H9O2PS2	220.3	C1=CC=C(C=C1)SCP(=S)(O)O	Ki = 460000 nM	Non binder
T35565	Alkaline phosphatase	B3QUS1	7-(Dihydroxyphosphinothioylmethyl)naphthalene-1-carboxylic Acid	Investigative	10379025	C12H11O4PS	282.25	C1=CC2=C(C=C(C=C2)CP(=S)(O)O)C(=C1)C(=O)O	Ki = 1500000 nM	Non binder
T35565	Alkaline phosphatase	B41KWB	3-Methoxy-8-(2H-tetrazol-5-yl)pyrido[2,1-b]quinazolin-11-one	Investigative	12762400	C14H10N6O2	294.27	COC1=CC2=C(C=C1)C(=O)N3C=C(C=CC3=N2)C4=NNN=N4	IC50 = 620000 nM	Non binder
T35565	Alkaline phosphatase	B46LUS	2,3-Dimethoxy-8-(2H-tetrazol-5-yl)pyrido[2,1-b]quinazolin-11-one	Investigative	13019730	C15H12N6O3	324.29	COC1=C(C=C2C(=C1)C(=O)N3C=C(C=CC3=N2)C4=NNN=N4)OC	IC50 = 340000 nM	Non binder
T35565	Alkaline phosphatase	B4HGS5	12-Oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxylic acid	Investigative	12473033	C17H10N2O3	290.27	C1=CC=C2C=C3C(=CC2=C1)C(=O)N4C=CC=C(C4=N3)C(=O)O	IC50 = 710000 nM	Non binder
T35565	Alkaline phosphatase	B4ZI2Y	2,3-Dihydroxy-11-oxopyrido[2,1-b]quinazoline-8-carboxylic acid	Investigative	12512364	C13H8N2O5	272.21	C1=CC2=NC3=CC(=C(C=C3C(=O)N2C=C1C(=O)O)O)O	IC50 = 220000 nM	Non binder
T35565	Alkaline phosphatase	B61TGI	6-Phosphonohexanoic Acid	Investigative	10921447	C6H13O5P	196.14	C(CCC(=O)O)CCP(=O)(O)O	Ki = 7000000 nM	Non binder
T35565	Alkaline phosphatase	B6A3NF	2-Methyl-8-(2H-tetrazol-5-yl)pyrido[2,1-b]quinazolin-11-one	Investigative	13019729	C14H10N6O	278.27	CC1=CC2=C(C=C1)N=C3C=CC(=CN3C2=O)C4=NNN=N4	IC50 = 210000 nM	Non binder
T35565	Alkaline phosphatase	B8DZW5	11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid	Investigative	198439	C13H8N2O3	240.21	C1=CC=C2C(=C1)C(=O)N3C=C(C=CC3=N2)C(=O)O	IC50 = 350000 nM	Non binder
T35565	Alkaline phosphatase	B8L3BF	6-Thiophosphono-hexanoic acid	Investigative	12124355	C6H13O4PS	212.21	C(CCC(=O)O)CCP(=S)(O)O	Ki = 1500000 nM	Non binder
T35565	Alkaline phosphatase	BCYM36	2,3-Dimethoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid	Investigative	12512360	C15H12N2O5	300.27	COC1=C(C=C2C(=C1)C(=O)N3C=C(C=CC3=N2)C(=O)O)OC	IC50 = 410000 nM	Non binder
T35565	Alkaline phosphatase	BF16UT	Methylphosphonothiolate	Investigative	197063	CH5O2PS	112.09	CP(=S)(O)O	Ki = 19000000 nM	Non binder
T35565	Alkaline phosphatase	BG5IE4	2-(2H-Tetrazol-5-yl)-12H-benzo[g]pyrido[2,1-b]quinazolin-12-one	Investigative	12762401	C17H10N6O	314.3	C1=CC=C2C=C3C(=CC2=C1)C(=O)N4C=C(C=CC4=N3)C5=NNN=N5	IC50 = 230000 nM	Non binder
T35565	Alkaline phosphatase	BGDQ31	Methyl 6-dihydroxyphosphinothioylhexanoate	Investigative	11151757	C7H15O4PS	226.23	COC(=O)CCCCCP(=S)(O)O	Ki = 330000 nM	Non binder
T35565	Alkaline phosphatase	BIF7Z0	8-(2H-Tetrazol-5-yl)pyrido[2,1-b]quinazolin-11-one	Investigative	13019728	C13H8N6O	264.24	C1=CC=C2C(=C1)C(=O)N3C=C(C=CC3=N2)C4=NNN=N4	IC50 = 280000 nM	Non binder
T35565	Alkaline phosphatase	BLD31Z	2,3,4,11-Tetrahydro-1H-pyrido[2,1-b]quinazoline-8-carboxylic acid	Investigative	44377473	C13H14N2O2	230.26	C1CCC2=C(C1)CN3C=C(C=CC3=N2)C(=O)O	IC50 > 10000000 nM	Non binder
T35565	Alkaline phosphatase	BNJ8L7	Butyl-phosphonothioic acid	Investigative	20262261	C4H11O2PS	154.17	CCCCP(=S)(O)O	Ki = 600000 nM	Non binder
T35565	Alkaline phosphatase	BO5W1U	11-Oxo-11H-pyrido[2,1-b]quinazoline-6-carboxylic acid	Investigative	646625	C13H8N2O3	240.21	C1=CC=C2C(=C1)C(=O)N3C=CC=C(C3=N2)C(=O)O	IC50 = 800000 nM	Non binder
T35565	Alkaline phosphatase	BPKG62	2-Hydroxy-11-oxopyrido[2,1-b]quinazoline-8-carboxylic acid	Investigative	12512356	C13H8N2O4	256.209	C1=CC2=C(C=C1O)C(=O)N3C=C(C=CC3=N2)C(=O)O	IC50 = 280000 nM	Non binder
T35565	Alkaline phosphatase	BQWA87	4-Oxopyrido[1,2-a]pyrimidine-7-carboxylic acid	Investigative	20555046	C9H6N2O3	190.16	C1=CC2=NC=CC(=O)N2C=C1C(=O)O	IC50 > 10000000 nM	Non binder
T35565	Alkaline phosphatase	BVL0G9	Methylphosphonic acid	Investigative	13818	CH5O3P	96.022	CP(=O)(O)O	Ki = 11000000 nM	Non binder
T35565	Alkaline phosphatase	BXK28Y	Benzylphosphonic acid	Investigative	81312	C7H9O3P	172.12	C1=CC=C(C=C1)CP(=O)(O)O	Ki = 580000 nM	Non binder
T35565	Alkaline phosphatase	BXM51S	6-(2H-Tetrazol-5-yl)-13,15-dioxa-2,8-diazatetracyclo[8.7.0.03,8.012,16]heptadeca-1(17),2,4,6,10,12(16)-hexaen-9-one	Investigative	13019731	C14H8N6O3	308.25	C1OC2=C(O1)C=C3C(=C2)C(=O)N4C=C(C=CC4=N3)C5=NNN=N5	IC50 = 230000 nM	Non binder
T35565	Alkaline phosphatase	BZ37BD	7-(Phosphonomethyl)-1-naphthoic acid	Investigative	10880008	C12H11O5P	266.19	C1=CC2=C(C=C(C=C2)CP(=O)(O)O)C(=C1)C(=O)O	Ki = 390000 nM	Non binder
T35565	Alkaline phosphatase	D01IGI	Disodium cromoglycate	Investigative	27503	C23H14Na2O11	512.299	C1=CC2=C(C(=C1)OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)[O-])O)C(=O)C=C(O2)C(=O)[O-].[Na+].[Na+]	IC50 = 9680000 nM	Non binder
T35565	Alkaline phosphatase	D0RC4F	BUFROLIN	Investigative	72103	C18H16N2O6	356.3	CCCCC1=CC2=C(C3=C1NC(=CC3=O)C(=O)O)NC(=CC2=O)C(=O)O	IC50 = 970000 nM	Non binder